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The Use of Electrospun Organic and Carbon Nanofibers in Bone Regeneration
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Applications of Carbon Nanotubes in Bone Regenerative Medicine

1
Department of Orthopaedic Surgery, Okaya City Hospital, 4-11-33 Honcho, Okaya, Nagano 394-8512, Japan
2
Physical Therapy Division, School of Health Sciences, Shinshu University, 3-1-1 Asahi, Matsumoto, Nagano 390-8621, Japan
3
Institute for Biomedical Sciences, Interdisciplinary Cluster for Cutting Edge Research, Shinshu University, 3-1-1 Asahi, Matsumoto, Nagano 390-8621, Japan
4
Department of Biomedical Engineering, Graduate School of Medicine, Science and Technology, Shinshu University, 3-1-1 Asahi, Matsumoto, Nagano 390-8621, Japan
5
Department of Orthopaedic Surgery, Shinshu University School of Medicine, 3-1-1 Asahi, Matsumoto, Nagano 390-8621, Japan
6
Department of Orthopaedic Surgery, Marunouchi Hospital, 1-7-45 Nagisa, Matsumoto, Nagano 390-8601, Japan
*
Author to whom correspondence should be addressed.
These authors contributed equally to this work.
Nanomaterials 2020, 10(4), 659; https://doi.org/10.3390/nano10040659
Received: 15 March 2020 / Revised: 28 March 2020 / Accepted: 29 March 2020 / Published: 2 April 2020
(This article belongs to the Special Issue Carbon-Based Nanomaterials for Bone Regeneration)
Scaffolds are essential for bone regeneration due to their ability to maintain a sustained release of growth factors and to provide a place where cells that form new bone can enter and proliferate. In recent years, scaffolds made of various materials have been developed and evaluated. Functionally effective scaffolds require excellent cell affinity, chemical properties, mechanical properties, and safety. Carbon nanotubes (CNTs) are fibrous nanoparticles with a nano-size diameter and have excellent strength and chemical stability. In the industrial field, they are used as fillers to improve the performance of materials. Because of their excellent physicochemical properties, CNTs are studied for their promising clinical applications as biomaterials. In this review article, we focused on the results of our research on CNT scaffolds for bone regeneration, introduced the promising properties of scaffolds for bone regeneration, and described the potential of CNT scaffolds. View Full-Text
Keywords: bone defects; scaffolds; carbon nanotubes; bone regeneration bone defects; scaffolds; carbon nanotubes; bone regeneration
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Tanaka, M.; Aoki, K.; Haniu, H.; Kamanaka, T.; Takizawa, T.; Sobajima, A.; Yoshida, K.; Okamoto, M.; Kato, H.; Saito, N. Applications of Carbon Nanotubes in Bone Regenerative Medicine. Nanomaterials 2020, 10, 659.

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