Next Article in Journal
Internalized FGF-2-Loaded Nanoparticles Increase Nuclear ERK1/2 Content and Result in Lung Cancer Cell Death
Previous Article in Journal
Effect of Dispersion Solvent on the Deposition of PVP-Silver Nanoparticles onto DBD Plasma-Treated Polyamide 6,6 Fabric and Its Antimicrobial Efficiency
Previous Article in Special Issue
Silica-Coated Magnetic Nanoparticles Decrease Human Bone Marrow-Derived Mesenchymal Stem Cell Migratory Activity by Reducing Membrane Fluidity and Impairing Focal Adhesion
Open AccessReview

Evaluation of Ecotoxicology Assessment Methods of Nanomaterials and Their Effects

Advanced Environmental Research Laboratories, Department of Biology—Chemistry, West University of Timisoara, Oituz 4, 300086 Timisoara, Romania
*
Author to whom correspondence should be addressed.
Nanomaterials 2020, 10(4), 610; https://doi.org/10.3390/nano10040610
Received: 28 February 2020 / Revised: 19 March 2020 / Accepted: 20 March 2020 / Published: 26 March 2020
(This article belongs to the Special Issue Nanotechnology for Environmental and Biomedical Research)
This paper describes the ecotoxicological effects of nanomaterials (NMs) as well as their testing methods. Standard ecotoxicity testing methods are applicable to nanomaterials as well but require some adaptation. We have taken into account methods that meet several conditions. They must be properly researched by a minimum of ten scientific articles where adaptation of the method to the NMs is also presented; use organisms suitable for simple and rapid ecotoxicity testing (SSRET); have a test period shorter than 30 days; require no special equipment; have low costs and have the possibility of optimization for high-throughput screening. From the standard assays described in guidelines developed by organizations such as Organization for Economic Cooperation and Development and United States Environmental Protection Agency, which meet the required conditions, we selected as methods adaptable for NMs, some methods based on algae, duckweed, amphipods, daphnids, chironomids, terrestrial plants, nematodes and earthworms. By analyzing the effects of NMs on a wide range of organisms, it has been observed that these effects can be of several categories, such as behavioral, morphological, cellular, molecular or genetic effects. By comparing the EC50 values of some NMs it has been observed that such values are available mainly for aquatic ecotoxicity, with the most sensitive test being the algae assay. The most toxic NMs overall were the silver NMs. View Full-Text
Keywords: nanomaterials; organisms suitable for simple and rapid ecotoxicity testing SSRET; ecotoxicological test batteries; ecotoxicology nanomaterials; organisms suitable for simple and rapid ecotoxicity testing SSRET; ecotoxicological test batteries; ecotoxicology
Show Figures

Graphical abstract

MDPI and ACS Style

Boros, B.-V.; Ostafe, V. Evaluation of Ecotoxicology Assessment Methods of Nanomaterials and Their Effects. Nanomaterials 2020, 10, 610.

Show more citation formats Show less citations formats
Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Article Access Map by Country/Region

1
Back to TopTop