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Open AccessArticle

Use of HER2-Directed Therapy in Metastatic Breast Cancer and How Community Physicians Collaborate to Improve Care

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Department of Medical Oncology and Therapeutics Research, City of Hope Comprehensive Cancer Center, Duarte, CA 91010, USA
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Department of Surgery, Division of Breast Surgery, City of Hope Comprehensive Cancer Center, Duarte, CA 91010, USA
*
Author to whom correspondence should be addressed.
J. Clin. Med. 2020, 9(6), 1984; https://doi.org/10.3390/jcm9061984
Received: 6 May 2020 / Revised: 10 June 2020 / Accepted: 18 June 2020 / Published: 24 June 2020
The development of new HER2-directed therapies has resulted in a significant prolongation of survival for women with metastatic HER2-positive breast cancer. Discoveries in the laboratory inform clinical trials which are the basis for improving the standard of care and are also the backbone for quality improvement. Clinical trials can be completed more rapidly by expanding trial enrollment to community sites. In this article we review some of the challenges in treating metastatic breast cancer with HER2-directed therapies and our strategies for incorporating our community partners into the research network. View Full-Text
Keywords: breast cancer; community; research; HER2-directed therapy breast cancer; community; research; HER2-directed therapy
MDPI and ACS Style

Mortimer, J.E.; Kruper, L.; Cianfrocca, M.; Lavasani, S.; Liu, S.; Tank-Patel, N.; Sedrak, M.; Smith, W.; Stewart, D.; Waisman, J.; Yeon, C.; Wang, T.; Yuan, Y. Use of HER2-Directed Therapy in Metastatic Breast Cancer and How Community Physicians Collaborate to Improve Care. J. Clin. Med. 2020, 9, 1984.

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