The Association between Delivery during the COVID-19 Pandemic and Immediate Postpartum Maternal Cognitive Function
Abstract
:1. Introduction
2. Materials and Methods
2.1. Population and Settings
2.2. Study Design
2.3. Statistical Analysis
3. Results
3.1. Study Groups
3.2. Pregnancy and Delivery Characteristics
3.3. Cognitive Tests
3.4. Multivariable Analyses
4. Discussion
5. Conclusions
Author Contributions
Funding
Acknowledgments
Conflicts of Interest
References
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Characteristics | During COVID-19 Pandemic n = 79 n (%) | Before COVID-19 Pandemic n = 123 n (%) | p-Value | |
---|---|---|---|---|
Maternal age, years (mean ± SD) | 28.1 ± 5.6 | 28.3 ± 5.1 | 0.836 | |
Country of birth | Israel | 85 (93.4) | 105 (88.2) | 0.206 |
Other | 6 (6.6) | 14 (11.8) | ||
Familial status | Married | 88 (98.9) | 93 (97.9) | 0.599 |
Other | 1 (1.1) | 2 (2.1) | ||
Ethnicity | Jewish | 40 (44) | 67 (56.8) | 0.066 |
Bedouin | 51 (56) | 51 (43.2) | ||
History of non-psychiatric chronic illness | 12 (14.1) | 16 (13.4) | 0.891 | |
EPDS score ≥ 10 | 26 (28.6) | 40 (34.5) | 0.365 | |
Gravidity | 1 | 17 (20) | 27 (22.7 | 0.798 |
2–4 | 49 (57.6) | 63 (52.9) | ||
5+ | 19 (22.4) | 29 (24.4) | ||
Time from admission to assessment (days) | 1.0 ± 0.8 | 1.6 ± 1.2 | <0.001 |
Characteristics | During COVID-19 Pandemic n = 79 n (%) | Before COVID-19 Pandemic n = 123 n (%) | p-Value | |
---|---|---|---|---|
Fertility treatments | 3 (3.6) | 10 (9.7) | 0.101 | |
Abnormal pregnancy screening tests 1 | 2 (2.2) | 9 (7.6) | 0.084 | |
Pregnancy complications 2 | GDM | 3 (3.5) | 5 (5) | 0.634 |
Preeclampsia | 0 (0) | 2 (1.7) | 0.222 | |
Birth weight (g) | 3179.5 ± 407.5 | 3233.4 ± 410.6 | 0.355 | |
Low birth weight | 2 (2.4) | 6 (5) | 0.329 | |
Gestational age at birth (weeks) | 39.2 ± 1.1 | 39.3 ± 1.1 | 0.355 |
Questionnaire | During COVID-19 Pandemic n = 79 | Before COVID-19 Pandemic n = 123 | p-Value |
---|---|---|---|
Objective cognitive test SDMT 90 (Mean ± SD) | 44.1 ± 13.7 | 45.0 ± 11.9 | 0.660 |
Objective cognitive test SDMT4 (Mean ± SD) | 116.9 ± 34.2 | 115.7 ± 30.5 | 0.794 |
Subjective cognitive test AFI (Mean ± SD) | 70.0 ± 15.4 | 75.1 ± 14.7 | 0.018 |
Variables | Beta | 95% CI | p-Value |
---|---|---|---|
Delivery during COVID-19 pandemic (vs. delivery before the COVID-19 pandemic) | −5.608 | −10.09; −1.13 | 0.014 |
Maternal age | 0.279 | −0.15; 0.7 | 0.198 |
Ethnicity | −0.854 | −5.57; 3.86 | 0.721 |
Time from admission to assessment | −0.974 | −3.15; 1.2 | 0.377 |
Variables | Beta | 95% CI | p-Value |
---|---|---|---|
Delivery during COVID-19 pandemic (vs. delivery before the COVID-19 pandemic) | 0.662 | −3.18; 4.51 | 0.734 |
Maternal age | −0.107 | −0.47; 0.26 | 0.567 |
Ethnicity | −9.531 | −13.56; −5.51 | <0.001 |
Time from admission to assessment | 0.363 | −1.56; 2.28 | 0.710 |
Variables | Beta | 95% CI | p-Value |
---|---|---|---|
Delivery during COVID-19 pandemic (vs. delivery before the COVID-19 pandemic) | 1.277 | −8.01; 10.56 | 0.786 |
Maternal age | −0.852 | −1.73; 0.03 | 0.058 |
Ethnicity | −24.283 | −34.12; −14.45 | <0.001 |
Time from admission to assessment | −2.828 | −7.56; 1.9 | 0.240 |
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Hamami, H.; Sheiner, E.; Wainstock, T.; Mazor, E.; Lanxner Battat, T.; Walfisch, A.; Kosef, T.; Pariente, G. The Association between Delivery during the COVID-19 Pandemic and Immediate Postpartum Maternal Cognitive Function. J. Clin. Med. 2020, 9, 3727. https://doi.org/10.3390/jcm9113727
Hamami H, Sheiner E, Wainstock T, Mazor E, Lanxner Battat T, Walfisch A, Kosef T, Pariente G. The Association between Delivery during the COVID-19 Pandemic and Immediate Postpartum Maternal Cognitive Function. Journal of Clinical Medicine. 2020; 9(11):3727. https://doi.org/10.3390/jcm9113727
Chicago/Turabian StyleHamami, Hagai, Eyal Sheiner, Tamar Wainstock, Elad Mazor, Talya Lanxner Battat, Asnat Walfisch, Tamar Kosef, and Gali Pariente. 2020. "The Association between Delivery during the COVID-19 Pandemic and Immediate Postpartum Maternal Cognitive Function" Journal of Clinical Medicine 9, no. 11: 3727. https://doi.org/10.3390/jcm9113727