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Open AccessFeature PaperReview

Hypertrophic Cardiomyopathy—Past, Present and Future

Royal Bournemouth Hospital, Bournemouth BH7 7DW, UK
Norwich Medical School, University of East Anglia; Norwich NR4 7UQ, UK
Norfolk and Norwich University Hospital, Norwich NR4 7UY, UK
Royal Brompton and Imperial College, London SW3 6NP, UK
Institute of Cardiovascular Medicine and Science, Liverpool Heart and Chest Hospital, Liverpool L14 3PE, UK
Imperial College NHS Foundation Trust, London SW7 2AZ, UK
Department of Cardiology, Imperial College NHS Foundation Trust, Hammersmith Hospital, Du Cane Road, London W12 0HS, UK
Author to whom correspondence should be addressed.
J. Clin. Med. 2017, 6(12), 118;
Received: 26 October 2017 / Revised: 21 November 2017 / Accepted: 5 December 2017 / Published: 12 December 2017
Hypertrophic cardiomyopathy (HCM) is the most common genetic cardiomyopathy with a prevalence of 1 in 500 in the general population. Since the first pathological case series at post mortem in 1957, we have come a long way in its understanding, diagnosis and management. Here, we will describe the history of our understanding of HCM including the initial disease findings, diagnostic methods and treatment options. We will review the current guidelines for the diagnosis and management of HCM, current gaps in the evidence base and discuss the new and promising developments in this field. View Full-Text
Keywords: hypertrophic cardiomyopathy; HCM; left ventricular outflow tract obstruction; LVOT hypertrophic cardiomyopathy; HCM; left ventricular outflow tract obstruction; LVOT
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Liew, A.C.; Vassiliou, V.S.; Cooper, R.; Raphael, C.E. Hypertrophic Cardiomyopathy—Past, Present and Future. J. Clin. Med. 2017, 6, 118.

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