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Article

Clinical Factors Associated with Atrial Fibrillation Detection on Single-Time Point Screening Using a Hand-Held Single-Lead ECG Device

1
Cardiology Division, Department of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, Policlinico di Modena, 41125 Modena, Italy
2
Cardiology Unit, “Card. G. Panico” Hospital, 73039 Tricase, Italy
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Clinical and Experimental Medicine PhD Program, University of Modena and Reggio Emilia, 41125 Modena, Italy
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German Cardiovascular Research Center (DZHK), Partner Site Hamburg/Kiel/Lübeck, University Heart and Vascular Centre, 20251 Hamburg, Germany
5
Heart Research Institute, Charles Perkins Centre, and Concord Hospital Cardiology, University of Sydney, Sydney 2006, Australia
*
Author to whom correspondence should be addressed.
Academic Editor: François Roubille
J. Clin. Med. 2021, 10(4), 729; https://doi.org/10.3390/jcm10040729
Received: 5 January 2021 / Revised: 5 February 2021 / Accepted: 8 February 2021 / Published: 12 February 2021
(This article belongs to the Section Cardiology)
Our aim was to assess the prevalence of unknown atrial fibrillation (AF) among adults during single-time point rhythm screening performed during meetings or social recreational activities organized by patient groups or volunteers. A total of 2814 subjects (median age 68 years) underwent AF screening by a handheld single-lead ECG device (MyDiagnostick). Overall, 56 subjects (2.0%) were diagnosed with AF, as a result of 12-lead ECG following a positive/suspected recording. Screening identified AF in 2.9% of the subjects ≥ 65 years. None of the 265 subjects aged below 50 years was found positive at AF screening. Risk stratification for unknown AF based on a CHA2DS2VASc > 0 in males and >1 in females (or CHA2DS2VA > 0) had a high sensitivity (98.2%) and a high negative predictive value (99.8%) for AF detection. A slightly lower sensitivity (96.4%) was achieved by using age ≥ 65 years as a risk stratifier. Conversely, raising the threshold at ≥75 years showed a low sensitivity. Within the subset of subjects aged ≥ 65 a CHA2DS2VASc > 1 in males and >2 in females, or a CHA2DS2VA > 1 had a high sensitivity (94.4%) and negative predictive value (99.3%), while age ≥ 75 was associated with a marked drop in sensitivity for AF detection. View Full-Text
Keywords: age; atrial fibrillation; risk stratification; stroke age; atrial fibrillation; risk stratification; stroke
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MDPI and ACS Style

Boriani, G.; Palmisano, P.; Malavasi, V.L.; Fantecchi, E.; Vitolo, M.; Bonini, N.; Imberti, J.F.; Valenti, A.C.; Schnabel, R.B.; Freedman, B. Clinical Factors Associated with Atrial Fibrillation Detection on Single-Time Point Screening Using a Hand-Held Single-Lead ECG Device. J. Clin. Med. 2021, 10, 729. https://doi.org/10.3390/jcm10040729

AMA Style

Boriani G, Palmisano P, Malavasi VL, Fantecchi E, Vitolo M, Bonini N, Imberti JF, Valenti AC, Schnabel RB, Freedman B. Clinical Factors Associated with Atrial Fibrillation Detection on Single-Time Point Screening Using a Hand-Held Single-Lead ECG Device. Journal of Clinical Medicine. 2021; 10(4):729. https://doi.org/10.3390/jcm10040729

Chicago/Turabian Style

Boriani, Giuseppe, Pietro Palmisano, Vincenzo L. Malavasi, Elisa Fantecchi, Marco Vitolo, Niccolo’ Bonini, Jacopo F. Imberti, Anna C. Valenti, Renate B. Schnabel, and Ben Freedman. 2021. "Clinical Factors Associated with Atrial Fibrillation Detection on Single-Time Point Screening Using a Hand-Held Single-Lead ECG Device" Journal of Clinical Medicine 10, no. 4: 729. https://doi.org/10.3390/jcm10040729

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