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Review

Cognitive Rehabilitation in Multiple Sclerosis in the Period from 2013 and 2021: A Narrative Review

Neurocentre Magendie, INSERM U 1215, Université de Bordeaux, 33077 Bordeaux, France
Academic Editor: Omar Cauli
Brain Sci. 2022, 12(1), 55; https://doi.org/10.3390/brainsci12010055
Received: 8 December 2021 / Revised: 27 December 2021 / Accepted: 27 December 2021 / Published: 30 December 2021
(This article belongs to the Topic Mechanisms and Treatments of Neurodegenerative Diseases)
Background: In recent years, several blinded randomized controlled trials (RCT) have been conducted on cognitive rehabilitation (CR) in adults with multiple sclerosis (MS). Objective: To review all blinded RCTs on CR in MS published since 2013. Methods: The National Library of Medicine database (Medline) and PSYCINFO were searched using the keywords MS and CR or cognitive training or NP rehabilitation or memory rehabilitation or attention rehabilitation. Results: After the exclusion of some papers not specifically focused on CR, a final list of 26 studies was established. The papers belong to three main categories: individual specific rehabilitation (8studies), group rehabilitation (4 studies), and computerized training (CT) (14 studies), while one study combined group rehabilitation and CT. Among the individual rehabilitation studies, 5 were devoted to memory, and most of the 19 other selected studies were about several cognitive domains. Most of the studies mainly concerned RRMS patients, except for 2 studies that were carried out exclusively in progressive forms. Despite the methodological limitations of some studies and the great heterogeneity of the protocols, the results are generally in favor of the efficacy of CR in neuropsychological tests. Conclusion: Recent blinded RCTs about CR in MS show promising results. View Full-Text
Keywords: multiple sclerosis; cognitive rehabilitation; cognition; memory; review multiple sclerosis; cognitive rehabilitation; cognition; memory; review
MDPI and ACS Style

Brochet, B. Cognitive Rehabilitation in Multiple Sclerosis in the Period from 2013 and 2021: A Narrative Review. Brain Sci. 2022, 12, 55. https://doi.org/10.3390/brainsci12010055

AMA Style

Brochet B. Cognitive Rehabilitation in Multiple Sclerosis in the Period from 2013 and 2021: A Narrative Review. Brain Sciences. 2022; 12(1):55. https://doi.org/10.3390/brainsci12010055

Chicago/Turabian Style

Brochet, Bruno. 2022. "Cognitive Rehabilitation in Multiple Sclerosis in the Period from 2013 and 2021: A Narrative Review" Brain Sciences 12, no. 1: 55. https://doi.org/10.3390/brainsci12010055

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