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Review

Photodynamic Therapy—An Up-to-Date Review

1
Faculty of Engineering in Foreign Languages, University Politehnica of Bucharest, 011061 Bucharest, Romania
2
Faculty of Applied Chemistry and Materials Science, University Politehnica of Bucharest, 011061 Bucharest, Romania
3
Research Institute of the University of Bucharest—ICUB, University of Bucharest, 050657 Bucharest, Romania
*
Author to whom correspondence should be addressed.
Academic Editor: Zivile Luksiene
Appl. Sci. 2021, 11(8), 3626; https://doi.org/10.3390/app11083626
Received: 20 March 2021 / Revised: 8 April 2021 / Accepted: 14 April 2021 / Published: 17 April 2021
The healing power of light has attracted interest for thousands of years. Scientific discoveries and technological advancements in the field have eventually led to the emergence of photodynamic therapy, which soon became a promising approach in treating a broad range of diseases. Based on the interaction between light, molecular oxygen, and various photosensitizers, photodynamic therapy represents a non-invasive, non-toxic, repeatable procedure for tumor treatment, wound healing, and pathogens inactivation. However, classic photosensitizing compounds impose limitations on their clinical applications. Aiming to overcome these drawbacks, nanotechnology came as a solution for improving targeting efficiency, release control, and solubility of traditional photosensitizers. This paper proposes a comprehensive path, starting with the photodynamic therapy mechanism, evolution over the years, integration of nanotechnology, and ending with a detailed review of the most important applications of this therapeutic approach. View Full-Text
Keywords: photodynamic therapy; photosensitizers; nanomaterials; cancer treatment; non-malignant diseases; antimicrobial applications photodynamic therapy; photosensitizers; nanomaterials; cancer treatment; non-malignant diseases; antimicrobial applications
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MDPI and ACS Style

Niculescu, A.-G.; Grumezescu, A.M. Photodynamic Therapy—An Up-to-Date Review. Appl. Sci. 2021, 11, 3626. https://doi.org/10.3390/app11083626

AMA Style

Niculescu A-G, Grumezescu AM. Photodynamic Therapy—An Up-to-Date Review. Applied Sciences. 2021; 11(8):3626. https://doi.org/10.3390/app11083626

Chicago/Turabian Style

Niculescu, Adelina-Gabriela, and Alexandru M. Grumezescu 2021. "Photodynamic Therapy—An Up-to-Date Review" Applied Sciences 11, no. 8: 3626. https://doi.org/10.3390/app11083626

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