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Microorganisms, Volume 9, Issue 10

October 2021 - 176 articles

Cover Story: Myxobacteria are abundant and virtually ubiquitous environmental organisms. They have large genomes and engage in complicated behaviours, including communal predation and multicellular fruiting body formation. Myxobacterial fruiting bodies were first described and pictured by Roland Thaxter in 1892, and in 2006, the first myxobacterial genome was sequenced. Fifteen years later, more than 160 myxobacterial sequences are publicly available, and our understanding of myxobacterial biology and evolution has been transformed as a consequence. View this paper.
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Articles (176)

  • Article
  • Open Access
7 Citations
5,197 Views
30 Pages

Staphylococcus aureus Transcriptome Data and Metabolic Modelling Investigate the Interplay of Ser/Thr Kinase PknB, Its Phosphatase Stp, the glmR/yvcK Regulon and the cdaA Operon for Metabolic Adaptation

  • Chunguang Liang,
  • Ana B. Rios-Miguel,
  • Marcel Jarick,
  • Priya Neurgaonkar,
  • Myriam Girard,
  • Patrice François,
  • Jacques Schrenzel,
  • Eslam S. Ibrahim,
  • Knut Ohlsen and
  • Thomas Dandekar

Serine/threonine kinase PknB and its corresponding phosphatase Stp are important regulators of many cell functions in the pathogen S. aureus. Genome-scale gene expression data of S. aureus strain NewHG (sigB+) elucidated their effect on physiological...

  • Article
  • Open Access
16 Citations
5,688 Views
15 Pages

Predicting the Role of the Human Gut Microbiome in Constipation Using Machine-Learning Methods: A Meta-Analysis

  • Yutao Chen,
  • Tong Wu,
  • Wenwei Lu,
  • Weiwei Yuan,
  • Mingluo Pan,
  • Yuan-Kun Lee,
  • Jianxin Zhao,
  • Hao Zhang,
  • Wei Chen and
  • Jinlin Zhu
  • + 1 author

(1) Background: Constipation is a common condition that affects the health and the quality of life of patients. Recent studies have suggested that the gut microbiome is associated with constipation, but these studies were mainly focused on a single r...

  • Article
  • Open Access
7 Citations
5,856 Views
8 Pages

In Vitro Synergism of Penicillin and Ceftriaxone against Enterococcus faecalis

  • Lara Thieme,
  • Simon Briggs,
  • Eamon Duffy,
  • Oliwia Makarewicz and
  • Mathias W. Pletz

Enterococcus faecalis infective endocarditis is commonly treated with intravenous ampicillin/ceftriaxone combination therapy. Ampicillin, however, is unsuitable for outpatient parenteral antibiotic therapy (OPAT) regimens due to its instability in 24...

  • Article
  • Open Access
26 Citations
4,118 Views
13 Pages

Lactic acid bacteria (LAB) are important microorganisms in food fermentation. In the food industry, bacteriophages (phages or bacterial viruses) may cause the disruption of LAB-dependent processes with product inconsistencies and economic losses. LAB...

  • Article
  • Open Access
2 Citations
3,263 Views
19 Pages

Investigations on the Degradation of the Bile Salt Cholate via the 9,10-Seco-Pathway Reveals the Formation of a Novel Recalcitrant Steroid Compound by a Side Reaction in Sphingobium sp. Strain Chol11

  • Franziska Maria Feller,
  • Sebastian Eilebrecht,
  • Ruslan Nedielkov,
  • Onur Yücel,
  • Julia Alvincz,
  • Gabriela Salinas,
  • Kevin Christopher Ludwig,
  • Heiko Möller and
  • Bodo Philipp

Bile salts such as cholate are steroid compounds from the digestive tracts of vertebrates, which enter the environment upon excretion, e.g., in manure. Environmental bacteria degrade bile salts aerobically via two pathway variants involving intermedi...

  • Case Report
  • Open Access
7 Citations
2,779 Views
7 Pages

Chromoblastomycosis Due to a Never-before-Seen Dematiaceous Fungus in a Kidney Transplant Patient

  • Hélène Guegan,
  • Marine Cailleaux,
  • François Le Gall,
  • Florence Robert-Gangneux and
  • Jean-Pierre Gangneux

Chromoblastomycosis is a neglected fungal infection of the epidermis and subcutaneous tissue that predominates in tropical areas and results from the traumatic inoculation of environmental dematiaceous filamentous fungi. We describe the case of an im...

  • Article
  • Open Access
19 Citations
3,468 Views
13 Pages

Effect of Environmental Exposures on the Gut Microbiota from Early Infancy to Two Years of Age

  • Kameron Y. Sugino,
  • Tengfei Ma,
  • Nigel Paneth and
  • Sarah S. Comstock

The gut microbiota undergoes rapid changes during infancy in response to early-life exposures. We have investigated how the infant gut bacterial community matures over time and how exposures such as human milk and antibiotic treatment alter gut micro...

  • Article
  • Open Access
25 Citations
5,457 Views
16 Pages

Lactic acid bacteria (LAB) are probiotic candidates that may restore the balance of microbiota populations in intestinal microbial ecosystems by controlling pathogens and thereby promoting host health. The goal of this study was to isolate potential...

  • Article
  • Open Access
26 Citations
5,183 Views
17 Pages

Consistent Prebiotic Effects of Carrot RG-I on the Gut Microbiota of Four Human Adult Donors in the SHIME® Model despite Baseline Individual Variability

  • Pieter Van den Abbeele,
  • Cindy Duysburgh,
  • Ilse Cleenwerck,
  • Ruud Albers,
  • Massimo Marzorati and
  • Annick Mercenier

The human gut microbiome is currently recognized to play a vital role in human biology and development, with diet as a major modulator. Therefore, novel indigestible polysaccharides that confer a health benefit upon their fermentation by the microbio...

  • Review
  • Open Access
26 Citations
4,733 Views
25 Pages

Myxobacteria are fascinating and complex microbes. They prey upon other members of the soil microbiome by secreting antimicrobial proteins and metabolites, and will undergo multicellular development if starved. The genome sequence of the model myxoba...

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Microorganisms - ISSN 2076-2607