Psychological Distress in Patients with Autoimmune Arthritis during the COVID-19 Induced Lockdown in Italy
Abstract
:1. Introduction
2. Materials and Methods
2.1. Inclusion Criteria
2.2. Procedures
2.3. Statistical Analysis
3. Results
4. Discussion
5. Conclusions
Author Contributions
Funding
Acknowledgments
Conflicts of Interest
References
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%Controls (n = 100) | %Patients (n = 100) | p ^ | ||
---|---|---|---|---|
Gender | Females | 59.0 | 72.0 | 0.005 |
Age | <50 years | 40.0 | 21.0 | 0.003 |
≥50 years | 60.0 | 79.0 | ||
Mean (sd) | 50.5 (20.4) | 57.7 (12.5) | 0.003 | |
BMI § | ≥25 | 36.0 | 51.0 | 0.032 |
Education | Graduate | 36.0 | 27.0 | ns |
Employment | Retired | 30.0 | 26.0 | ns |
Smoking | Current smoker | 10.0 | 25.0 | 0.005 |
Alcohol Use | Yes vs. no | 75.0 | 59.0 | 0.016 |
Living | Alone | 39.0 | 37.0 | ns |
Comorbidity | ≥1 | 33.0 | 52.0 | 0.007 |
Depression, Anxiety and Stress Scale-21 (DASS-21) | ||||
DASS-21 Depression | No (score 0–9) | 64.0 | 58.0 | 0.029 |
Mild-moderate (score 10–20) | 32.0 | 27.0 | ||
Severe-extremely severe (score ≥ 21) | 4.0 | 15.0 | ||
Mean (sd) | 7.7 (6.6) | 10.3 (9.3) | 0.022 | |
DASS-21 Anxiety | No (score 0–7) | 75.0 | 62.0 | ns |
Mild-moderate (score 8–14) | 17.0 | 22.0 | ||
Severe-extremely severe (score ≥ 15) | 8.0 | 16.0 | ||
Mean (sd) | 5.1 (5.8) | 7.3 (7.7) | 0.020 | |
DASS-21 Stress | No (score 0–14) | 68.0 | 54.0 | 0.032 |
Mild-moderate (score 15–25) | 27.0 | 31.0 | ||
Severe-extremely severe (score ≥ 26) | 5.0 | 15.0 | ||
Mean (sd) | 11.3 (8.2) | 14.8 (8.8) | 0.005 | |
COVID-19 Peritraumatic Distress Index (CPDI) | ||||
No (score 0–27) | 77.0 | 59.0 | 0.022 | |
Mild-moderate (score 28–51) | 22.0 | 38.0 | ||
Severe-extremely severe (score 52–100) | 1.0 | 3.0 | ||
Mean (sd) | 19.3 (12.3) | 25.6 (12.7) | <0.001 | |
Perceived General Health * | Worse | 7.0 | 36.0 | <0.001 |
Mean (sd) | 2.9 (0.5) | 3.3 (0.8) | <0.001 | |
Perceived Fatigue * | Worse | 19.0 | 31.0 | ns |
Mean (sd) | 2.9 (0.8) | 3.2 (0.8) | 0.041 | |
Perceived Emotional Status * | Worse | 54.0 | 56.0 | ns |
Mean (sd) | 3.6 (0.8) | 3.6 (0.8) | ns | |
Perceived Disease Activity * | Worse | 37.0 | ||
Mean (sd) | / | 3.3 (0.8) | ||
Perceived Joint Pain * | Worse | 38.0 | ||
Mean (sd) | / | 3.3 (0.9) |
b | 95% CI | p | |||
---|---|---|---|---|---|
Cases | 3.6 | 0.76 | 6.76 | 0.014 | |
Gender | Females | 1.53 | −1.69 | 4.76 | ns |
Age | ≥50 | −1.58 | −5.12 | 1.97 | ns |
BMI § | ≥25 | 2.28 | −0.90 | 5.35 | ns |
Education | Graduate | 0.80 | −2.38 | 3.99 | ns |
Employment | Retired | 1.40 | −2.23 | 5.02 | ns |
Smoking | Current smokers | 0.97 | −2.80 | 4.74 | ns |
Alcohol | Yes vs no | 0.88 | −2.25 | 4.01 | ns |
Living | Alone | −0.05 | −2.89 | 3.00 | ns |
DASS-21 Depression | Mild–Moderate and Severe-extremely severe | 4.70 | 0.81 | 8.59 | 0.018 |
DASS-21 Anxiety | Mild–Moderate and Severe-extremely severe | 8.05 | 4.54 | 11.56 | <0.001 |
DASS-21 Stress | Mild–Moderate and Severe-extremely severe | 7.64 | 4.02 | 11.27 | <0.001 |
Comorbidity | ≥1 | 0.44 | −2.67 | 3.56 | ns |
OR | 95% CI | p | |||
---|---|---|---|---|---|
Cases | 9.01 | 3.11 | 26.07 | <0.001 | |
Gender | Females | 2.98 | 0.98 | 9.02 | ns |
Age | ≥50 | 0.39 | 0.13 | 1.17 | ns |
BMI § | ≥25 | 0.68 | 0.26 | 1.76 | ns |
Education | Graduate | 0.93 | 0.35 | 2.52 | ns |
Employment | Retired | 1.34 | 0.43 | 4.13 | ns |
Smoking | Current smokers | 0.80 | 0.29 | 2.26 | ns |
Alcohol | Yes vs. no | 0.79 | 0.31 | 2.00 | ns |
Living | Alone | 0.49 | 0.19 | 1.25 | ns |
Depression | Mild–Moderate and Severe-extremely severe | 0.68 | 0.20 | 2.26 | ns |
Anxiety | Mild–Moderate and Severe-extremely severe | 1.66 | 0.57 | 4.85 | ns |
Stress | Mild–Moderate and Severe-extremely severe | 1.94 | 0.62 | 6.06 | ns |
Comorbidity | ≥1 | 0.78 | 0.28 | 2.17 | ns |
CPDI ^ | Mild-Moderate and Severe | 5.56 | 2.06 | 14.99 | <0.001 |
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Picchianti Diamanti, A.; Cattaruzza, M.S.; Di Rosa, R.; Del Porto, F.; Salemi, S.; Sorgi, M.L.; Martin Martin, L.S.; Rai, A.; Iacono, D.; Sesti, G.; et al. Psychological Distress in Patients with Autoimmune Arthritis during the COVID-19 Induced Lockdown in Italy. Microorganisms 2020, 8, 1818. https://doi.org/10.3390/microorganisms8111818
Picchianti Diamanti A, Cattaruzza MS, Di Rosa R, Del Porto F, Salemi S, Sorgi ML, Martin Martin LS, Rai A, Iacono D, Sesti G, et al. Psychological Distress in Patients with Autoimmune Arthritis during the COVID-19 Induced Lockdown in Italy. Microorganisms. 2020; 8(11):1818. https://doi.org/10.3390/microorganisms8111818
Chicago/Turabian StylePicchianti Diamanti, Andrea, Maria Sofia Cattaruzza, Roberta Di Rosa, Flavia Del Porto, Simonetta Salemi, Maria Laura Sorgi, Luis Severino Martin Martin, Alessandra Rai, Dalila Iacono, Giorgio Sesti, and et al. 2020. "Psychological Distress in Patients with Autoimmune Arthritis during the COVID-19 Induced Lockdown in Italy" Microorganisms 8, no. 11: 1818. https://doi.org/10.3390/microorganisms8111818
APA StylePicchianti Diamanti, A., Cattaruzza, M. S., Di Rosa, R., Del Porto, F., Salemi, S., Sorgi, M. L., Martin Martin, L. S., Rai, A., Iacono, D., Sesti, G., Alessandri, G., & Laganà, B. (2020). Psychological Distress in Patients with Autoimmune Arthritis during the COVID-19 Induced Lockdown in Italy. Microorganisms, 8(11), 1818. https://doi.org/10.3390/microorganisms8111818