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Microorganisms, Volume 10, Issue 7

July 2022 - 222 articles

Cover Story: Probiotics are bacteria and yeast that provide human host health benefits. Limosilactobacillus reuteri DSM 20016 is a lactic acid bacterium that is found natively within the human gut. Genomic and metabolomic analyses of this strain highlighted 200 genes that were involved in metabolic pathways that could produce human host health benefits. Pathways to produce short-chain fatty acids, antimicrobial reuterin, TNF-suppressive histamine, and several vitamins as well as amino acids have been characterized. The strain is also able to adhere to the gut, compete against enteric bacteria, and withstand the hostile gut environment. L. reuteri DSM 20016 could be an advantageous addition to the human microbiota for preventing and treating certain inflammatory diseases, as well as in regulating dysbiosis. View this paper
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Articles (222)

  • Article
  • Open Access
34 Citations
3,899 Views
12 Pages

Infantis has recently become one of the most common serotypes of Salmonella isolated in the U.S. from raw meat samples collected in processing facilities and in retail stores. Investigations have determined that the majority of these isolates contain...

  • Article
  • Open Access
10 Citations
3,534 Views
13 Pages

Characterization of Clostridioides difficile Strains from an Outbreak Using MALDI-TOF Mass Spectrometry

  • Adriana Calderaro,
  • Mirko Buttrini,
  • Benedetta Farina,
  • Sara Montecchini,
  • Monica Martinelli,
  • Maria Cristina Arcangeletti,
  • Carlo Chezzi and
  • Flora De Conto

The epidemiology of Clostridioides difficile infection (CDI) has changed over the last two decades, due to the emergence of C. difficile strains with clinical relevance and responsible for nosocomial outbreaks with severe outcomes. This study reports...

  • Article
  • Open Access
2,704 Views
12 Pages

Streptococcus pyogenes NAD+-Glycohydrolase Reduces Skeletal Muscle βNAD+ Levels Independently of Streptolysin O

  • Eric R. McIndoo,
  • Emily Price,
  • Cheri L. Lamb,
  • Christopher S. Dayton,
  • Clifford R. Bayer,
  • Dennis L. Stevens,
  • Amy E. Bryant and
  • Sarah E. Hobdey

Necrotizing soft tissue infections caused by Streptococcus pyogenes (group A streptococcus [GAS]) are characterized by rapid and extensive necrosis of fascia and muscle. Molecular epidemiological studies have demonstrated a positive correlation betwe...

  • Article
  • Open Access
37 Citations
4,113 Views
11 Pages

The Combination of Molnupiravir with Nirmatrelvir or GC376 Has a Synergic Role in the Inhibition of SARS-CoV-2 Replication In Vitro

  • Anna Gidari,
  • Samuele Sabbatini,
  • Elisabetta Schiaroli,
  • Sabrina Bastianelli,
  • Sara Pierucci,
  • Chiara Busti,
  • Lucia Comez,
  • Valeria Libera,
  • Antonio Macchiarulo and
  • Alessandro Paciaroni
  • + 3 authors

Introduction: The development of effective vaccines has partially mitigated the trend of the SARS-CoV-2 pandemic; however, the need for orally administered antiviral drugs persists. This study aims to investigate the activity of molnupiravir in combi...

  • Article
  • Open Access
22 Citations
4,528 Views
15 Pages

Gut microbiota performs indispensable functions in the pathophysiology of alcoholic hepatitis (AH). We investigated the effects of Lacticaseibacillus rhamnosus R0011 and Lactobacillus helveticus for gut microbial restoration toward eubiosis in patien...

  • Article
  • Open Access
16 Citations
3,608 Views
14 Pages

The freshwater green microalgae, Dictyosphaerium chlorelloides (CCALA 330), has the ability to produce extracellular polysaccharides (EPS). Conditions for optimum growth and EPS overproduction were determined in laboratory-scale tubular photobioreact...

  • Article
  • Open Access
1 Citations
2,320 Views
16 Pages

Escherichia coli, a major pathogen in poultry production, is involved in femoral head necrosis (FHN) in broiler birds. So far, the characterization and relationship of isolates in context with this disease are mainly based on phenotypic and genotypic...

  • Article
  • Open Access
13 Citations
5,636 Views
23 Pages

iChip-Inspired Isolation, Bioactivities and Dereplication of Actinomycetota from Portuguese Beach Sediments

  • José Diogo Neves dos Santos,
  • Susana Afonso João,
  • Jesús Martín,
  • Francisca Vicente,
  • Fernando Reyes and
  • Olga Maria Lage

Oceans hold a stunning number of unique microorganisms, which remain unstudied by culture-dependent methods due to failures in establishing the right conditions for these organisms to grow. In this work, an isolation effort inspired by the iChip was...

  • Article
  • Open Access
11 Citations
4,682 Views
18 Pages

Adaptation of Brucella melitensis Antimicrobial Susceptibility Testing to the ISO 20776 Standard and Validation of the Method

  • Alina Tscherne,
  • Enrico Mantel,
  • Talar Boskani,
  • Sylwia Budniak,
  • Mandy Elschner,
  • Antonio Fasanella,
  • Siri L. Feruglio,
  • Domenico Galante,
  • Christian G. Giske and
  • Roland Grunow
  • + 21 authors

Brucellosis, mainly caused by Brucella (B.) melitensis, is associated with a risk of chronification and relapses. Antimicrobial susceptibility testing (AST) standards for B. melitensis are not available, and the agent is not yet listed in the EUCAST...

  • Article
  • Open Access
15 Citations
3,131 Views
18 Pages

The production performance and disease resistance of laying hens decrease obviously with age. This study aimed to investigate the effects of supplementary Lactobacillus salivarius (L. salivarius) SNK-6 on laying performance, the immune-related gene e...

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Microorganisms - ISSN 2076-2607