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Pathogens, Volume 3, Issue 1

March 2014 - 14 articles

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Articles (14)

  • Article
  • Open Access
21 Citations
10,105 Views
27 Pages

Genome Sequencing of Xanthomonas vasicola Pathovar vasculorum Reveals Variation in Plasmids and Genes Encoding Lipopolysaccharide Synthesis, Type-IV Pilus and Type-III Secretion Effectors

  • Arthur Wasukira,
  • Max Coulter,
  • Noorah Al-Sowayeh,
  • Richard Thwaites,
  • Konrad Paszkiewicz,
  • Jerome Kubiriba,
  • Julian Smith,
  • Murray Grant and
  • David J. Studholme

18 March 2014

Xanthomonas vasicola pathovar vasculorum (Xvv) is the bacterial agent causing gumming disease in sugarcane. Here, we compare complete genome sequences for five isolates of Xvv originating from sugarcane and one from maize. This identified two distinc...

  • Review
  • Open Access
47 Citations
15,001 Views
24 Pages

28 February 2014

Trillions of microorganisms that inhabit the intestinal tract form a diverse and intricate ecosystem with a deeply embedded symbiotic relationship with their hosts. As more detailed information on gut microbiota complexity and functional diversity ac...

  • Review
  • Open Access
15 Citations
8,158 Views
21 Pages

25 February 2014

Rapid adaptation to fluctuations in the host milieu contributes to the host persistence and virulence of bacterial pathogens. Adaptation is frequently mediated by hypermutable sequences in bacterial pathogens. Early bacterial genomic studies identifi...

  • Review
  • Open Access
16 Citations
7,586 Views
15 Pages

Prions and Prion-Like Pathogens in Neurodegenerative Disorders

  • Caterina Peggion,
  • Maria Catia Sorgato and
  • Alessandro Bertoli

18 February 2014

Prions are unique elements in biology, being able to transmit biological information from one organism to another in the absence of nucleic acids. They have been identified as self-replicating proteinaceous agents responsible for the onset of rare an...

  • Article
  • Open Access
14 Citations
9,039 Views
28 Pages

28 January 2014

The Pseudomonas syringae species complex has recently been named the number one plant pathogen, due to its economic and environmental impacts, as well as for its role in scientific research. The bacterium has been repeatedly reported to cause outbrea...

  • Article
  • Open Access
24 Citations
8,647 Views
12 Pages

22 January 2014

The mammalian gut houses a complex microbial community which is believed to play a significant role in host physiology. In recent years, several microbial community analysis methods have been implemented to study the whole gut microbial environment,...

  • Article
  • Open Access
6 Citations
9,832 Views
16 Pages

Live Genomics for Pathogen Monitoring in Public Health

  • Giuseppe D'Auria,
  • Maria Victoria Schneider and
  • Andrés Moya

21 January 2014

Whole genome analysis based on next generation sequencing (NGS) now represents an affordable framework in public health systems. Robust analytical pipelines of genomic data provides in short laps of time (hours) information about taxonomy, comparativ...

  • Review
  • Open Access
55 Citations
12,795 Views
20 Pages

16 January 2014

The cells that line the mucosa of the human gastrointestinal tract (GI, that is, oral cavity, oesophagus, stomach, small intestine, large intestine, and rectum) are constantly challenged by adverse micro-environmental factors, such as different pH, e...

  • Article
  • Open Access
13 Citations
8,446 Views
16 Pages

Genetic Diversity of Tick-Borne Rickettsial Pathogens; Insights Gained from Distant Strains

  • Sebastián Aguilar Pierlé,
  • Ivan Imaz-Rosshandler,
  • Ammielle Akim Kerudin,
  • Jacqueline Sambono,
  • Ala Lew-Tabor,
  • Peter Rolls,
  • Claudia Rangel-Escareño and
  • Kelly A. Brayton

14 January 2014

The ability to capture genetic variation with unprecedented resolution improves our understanding of bacterial populations and their ability to cause disease. The goal of the pathogenomics era is to define genetic diversity that results in disease. D...

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Pathogens - ISSN 2076-0817