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Epigenomes, Volume 3, Issue 3 (September 2019)
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Cover Story (view full-size image) Behavioral epigenetics studies how epigenetic alterations induced by experience and environmental [...] Read more. Behavioral epigenetics studies how epigenetic alterations induced by experience and environmental stress may affect animal behavior. Adverse experiences from biological inheritance and parenting refer to what happened in life—for instance, childhood abuse, social defeat stress (socially isolated) and contact with toxins, etc. These experiences are factors that may influence epigenetic profiles such as DNA methylation and histone modifications that may potentially impact gene expression. For example, adverse maternal care provided during childhood was found to associate with increased DNA methylation of the NR3C1 gene and the decreased binding of transcriptional factor NGFI-A to the promoter of the NR3C1 gene. View this paper.