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Review

The Role of Molecular Imaging in a Muscle-Invasive Bladder Cancer Patient: A Narrative Review in the Era of Multimodality Treatment

1
Nuclear Medicine Unit, Department of Precision Medicine, Università della Campania “Luigi Vanvitelli”, 81100 Napoli, Italy
2
Nuclear Medicine Division, European Institute of Oncology, 20144 Milan, Italy
3
Nuclear Medicine Unit, Department of Diagnostic Imaging, Magna Graecia University of Catanzaro, 88100 Catanzaro, Italy
4
Unit of Urology, Magna Graecia University, 88100 Catanzaro, Italy
*
Author to whom correspondence should be addressed.
Academic Editors: Hidehiko Okazawa and Zhen Cheng
Diagnostics 2021, 11(5), 863; https://doi.org/10.3390/diagnostics11050863
Received: 22 March 2021 / Revised: 4 May 2021 / Accepted: 8 May 2021 / Published: 11 May 2021
(This article belongs to the Section Medical Imaging)
Diagnostic imaging in bladder cancer plays an important role since it is needed from pretreatment staging to follow-up, but a morphological evaluation performed with both CT and MRI showed low sensitivities and specificities in detecting pathologic lymph nodes, due to the occurrence of false positive results. Implementation of functional information provided by PET/CT could be a determinant in the management of patients with muscle-invasive bladder cancer. A focus on the role of 18F-FDG PET/CT and alternative tracers in patients with muscle-invasive bladder cancer is provided in this analysis in order to outline its potential applications in staging settings and response evaluation after neoadjuvant chemotherapy. View Full-Text
Keywords: bladder cancer; nuclear medicine; diagnostic imaging; restaging; response evaluation; PET/CT; hybrid imaging bladder cancer; nuclear medicine; diagnostic imaging; restaging; response evaluation; PET/CT; hybrid imaging
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MDPI and ACS Style

Cuccurullo, V.; Di Stasio, G.D.; Manti, F.; Arcuri, P.; Damiano, R.; Cascini, G.L. The Role of Molecular Imaging in a Muscle-Invasive Bladder Cancer Patient: A Narrative Review in the Era of Multimodality Treatment. Diagnostics 2021, 11, 863. https://doi.org/10.3390/diagnostics11050863

AMA Style

Cuccurullo V, Di Stasio GD, Manti F, Arcuri P, Damiano R, Cascini GL. The Role of Molecular Imaging in a Muscle-Invasive Bladder Cancer Patient: A Narrative Review in the Era of Multimodality Treatment. Diagnostics. 2021; 11(5):863. https://doi.org/10.3390/diagnostics11050863

Chicago/Turabian Style

Cuccurullo, Vincenzo, Giuseppe D. Di Stasio, Francesco Manti, Pierpaolo Arcuri, Rocco Damiano, and Giuseppe L. Cascini 2021. "The Role of Molecular Imaging in a Muscle-Invasive Bladder Cancer Patient: A Narrative Review in the Era of Multimodality Treatment" Diagnostics 11, no. 5: 863. https://doi.org/10.3390/diagnostics11050863

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