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Open AccessArticle

Plausible Emergence of Autocatalytic Cycles under Prebiotic Conditions

1
Department of Pharmacy, University of Salerno, Via Giovanni Paolo II, 132, 84084 Fisciano SA, Italy
2
Department of Industrial Engineering, University of Salerno, Via Giovanni Paolo II, 132, 84084 Fisciano SA, Italy
*
Author to whom correspondence should be addressed.
Received: 7 January 2019 / Revised: 22 March 2019 / Accepted: 2 April 2019 / Published: 4 April 2019
The emergence of life in a prebiotic world is an enormous scientific question of paramount philosophical importance. Even when life (in any sense we can define it) can be observed and replicated in the laboratory, it is only an indication of one possible pathway for life emergence, and is by no means be a demonstration of how life really emerged. The best we can hope for is to indicate plausible chemical–physical conditions and mechanisms that might lead to self-organizing and autopoietic systems. Here we present a stochastic simulation, based on chemical reactions already observed in prebiotic environments, that might help in the design of new experiments. We will show how the definition of simple rules for the synthesis of random peptides may lead to the appearance of networks of autocatalytic cycles and the emergence of memory. View Full-Text
Keywords: origin of life; hypercycle; Monte Carlo origin of life; hypercycle; Monte Carlo
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MDPI and ACS Style

Piotto, S.; Sessa, L.; Piotto, A.; Nardiello, A.M.; Concilio, S. Plausible Emergence of Autocatalytic Cycles under Prebiotic Conditions. Life 2019, 9, 33.

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