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A Dynamic Simulation of the Immune System Response to Inhibit and Eliminate Abnormal Cells

1
Department of Mathematics & Statistics, College of Science, Taibah University, 41911 Yanbu, Almadinah Almunawarah, Saudi Arabia
2
Mathematics Program, Faculty of Science & Technology, Universiti Kebangsaan Malaysia, 43600 UKM Bangi, Selangor, Malaysia
*
Author to whom correspondence should be addressed.
Symmetry 2019, 11(4), 572; https://doi.org/10.3390/sym11040572
Received: 15 March 2019 / Revised: 10 April 2019 / Accepted: 12 April 2019 / Published: 19 April 2019
(This article belongs to the Special Issue Symmetry in Mathematical Analysis and Applications)
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Abstract

Diet has long been considered a risk factor related to an increased risk of cancer. This challenges us to understand the relationship between the immune system and diet when abnormal cells appear in a tissue. In this paper, we propose and analyze a model from the point of view of a person who follows a healthy diet, i.e., one correlated to the food pyramid, and a person who follows an unhealthy diet. Normal cells and immune cells are used in the design of the model, which aims to describe how the immune system functions when abnormal cells appear in a tissue. The results show that the immune system is able to inhibit and eliminate abnormal cells through the three following stages: the response stage, the interaction stage, and the recovery stage. Specifically, the failure of the immune system to accomplish the interaction stage occurs when a person follows an unhealthy diet. According to the analysis and simulation of our model, we can deduce that dietary pattern has a significant impact on the functioning of the immune system. View Full-Text
Keywords: dynamic model; immune system response; immune cells; abnormal cells; nonlinear ordinary differential equations; stability; diet dynamic model; immune system response; immune cells; abnormal cells; nonlinear ordinary differential equations; stability; diet
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Alharbi, S.A.; Rambely, A.S. A Dynamic Simulation of the Immune System Response to Inhibit and Eliminate Abnormal Cells. Symmetry 2019, 11, 572.

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