In the original publication [1], corrections were made to Figure 5 and to the title of Section 2.5 in Materials and Methods, and the Informed Consent Statement was added.
Error in Figure 5
There was a mistake in Figure 5C as published. In Figure 5C, the edge connecting HIF1A and CDKN1A was incorrectly shown as a coherent edge. This edge is not coherent and should be represented as a thin line indicating incoherence. The corrected Figure 5 appears below.
Figure 5.
In-silico chemical screening of VEGFA inhibitors with CDKN1A activation properties. (A) The GRN network in Figure 4E was extended by adding genes from the KEGG pathway. (B) Upstream chemicals predicted as present in ALIEX basal vs. O1 basal and ALIEX secretory vs. O1 secretory DE results that regulate any of the 8 target genes (VEGFA, CDKN1A, HIF1A, BMP4, CXCR4, EPHA2, CASP3, and KDM5B). * indicates a chemical that downregulates VEGFA and upregulates CDKN1A. (C) GRN graph summarizing the regulatory effects of selected chemicals on the target genes.
Text Correction
There was an error in 2. Materials and Methods: the title of Section 2.5 misspelled Psudotime. The corrected title is as follows:
2.5. RNA Velocity and Pseudotime Analyses
Missing Informed Consent Statement
The Informed Consent Statement was not stated. The Informed Consent Statement has now been inserted by adding the following Informed Consent Statement section as below.
Informed Consent Statement: Informed consent was obtained from all subjects involved in the study.
The authors state that the scientific conclusions are unaffected. This correction was approved by the Academic Editor. The original publication has also been updated.
Reference
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