NLRP3 and Gut Microbiota Homeostasis: Progress in Research
Abstract
:1. Introduction
2. Inflammasome and Innate Immunity
3. Gut Immunity and Gut Microbiota
3.1. Gut Microbiota Is Essential for Gut Immunity
3.2. The Gut Microbiota Disorder Is Associated with the Pathogenesis of Various Diseases
4. The Relationship between the NLRP3 Inflammasome and Intestinal Homeostasis
4.1. NLRP3 Inflammasome Plays a Key Role in Intestinal Mucosal Immunity
4.2. Downstream Effector IL-1
4.3. Downstream Effector IL-18
4.4. NLRP3 Inflammasome and Gasdermin D
5. Conclusions
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Acknowledgments
Conflicts of Interest
References
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Pan, H.; Jian, Y.; Wang, F.; Yu, S.; Guo, J.; Kan, J.; Guo, W. NLRP3 and Gut Microbiota Homeostasis: Progress in Research. Cells 2022, 11, 3758. https://doi.org/10.3390/cells11233758
Pan H, Jian Y, Wang F, Yu S, Guo J, Kan J, Guo W. NLRP3 and Gut Microbiota Homeostasis: Progress in Research. Cells. 2022; 11(23):3758. https://doi.org/10.3390/cells11233758
Chicago/Turabian StylePan, Hongming, Yuting Jian, Feijie Wang, Shaokun Yu, Jiannan Guo, Juntao Kan, and Wei Guo. 2022. "NLRP3 and Gut Microbiota Homeostasis: Progress in Research" Cells 11, no. 23: 3758. https://doi.org/10.3390/cells11233758