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Polymers 2017, 9(7), 248;

Chestnut Honey Impregnated Carboxymethyl Cellulose Hydrogel for Diabetic Ulcer Healing

Advanced Radiation Technology Institute, Korea Atomic Energy Research Institute, 1266 Sinjeong-dong, Jeongeup-si, Jeollabuk-do 580-185, Korea
Author to whom correspondence should be addressed.
Academic Editor: Esmaiel Jabbari
Received: 5 May 2017 / Revised: 9 June 2017 / Accepted: 23 June 2017 / Published: 27 June 2017
(This article belongs to the Special Issue Hydrogels in Tissue Engineering and Regenerative Medicine)
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Honey-based wound dressings have attracted a lot of attention from modern scientists owing to their anti-inflammatory and antibacterial effects without antibiotic resistance. Such dressings also promote moist wound healing, and have been considered natural, abundant, and cheap materials for folk marketing. This study investigated the various behaviors and characteristics of chestnut honey-impregnated carboxymethyl cellulose sodium hydrogel paste (CH–CMC) as a therapeutic dressing, such as its moist retention, antibacterial activity for inhibiting the growth of Staphylococcus aureus and Escherichia coli, and the rate of wound healing in db/db mice. The results provide good evidence, suggesting that CH–CMC has potential as a competitive candidate for diabetic ulcer wound healing. View Full-Text
Keywords: chestnut honey; CMC hydrogel; γ-irradiation; wound dressing chestnut honey; CMC hydrogel; γ-irradiation; wound dressing

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Park, J.-S.; An, S.-J.; Jeong, S.-I.; Gwon, H.-J.; Lim, Y.-M.; Nho, Y.-C. Chestnut Honey Impregnated Carboxymethyl Cellulose Hydrogel for Diabetic Ulcer Healing. Polymers 2017, 9, 248.

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