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Open AccessReview

Stimuli-Directed Helical Chirality Inversion and Bio-Applications

State Key Laboratory of Advanced Technology for Materials Synthesis and Processing, Wuhan University of Technology, 122 Luoshi Road, Wuhan 430070, China
School of Chemistry, Chemical Engineering and Life Science, Wuhan University of Technology, 122 Luoshi Road, Wuhan 430070, China
Authors to whom correspondence should be addressed.
Academic Editor: Shiyong Liu
Polymers 2016, 8(8), 310;
Received: 21 July 2016 / Revised: 9 August 2016 / Accepted: 12 August 2016 / Published: 18 August 2016
Helical structure is a sophisticated ubiquitous motif found in nature, in artificial polymers, and in supramolecular assemblies from microscopic to macroscopic points of view. Significant progress has been made in the synthesis and structural elucidation of helical polymers, nevertheless, a new direction for helical polymeric materials, is how to design smart systems with controllable helical chirality, and further use them to develop chiral functional materials and promote their applications in biology, biochemistry, medicine, and nanotechnology fields. This review summarizes the recent progress in the development of high-performance systems with tunable helical chirality on receiving external stimuli and discusses advances in their applications as drug delivery vesicles, sensors, molecular switches, and liquid crystals. Challenges and opportunities in this emerging area are also presented in the conclusion. View Full-Text
Keywords: helical chirality; stimuli-responsive; supramolecular assembly; helical polymer helical chirality; stimuli-responsive; supramolecular assembly; helical polymer
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MDPI and ACS Style

Lv, Z.; Chen, Z.; Shao, K.; Qing, G.; Sun, T. Stimuli-Directed Helical Chirality Inversion and Bio-Applications. Polymers 2016, 8, 310.

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