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Polymers 2018, 10(6), 650;

Recent Advances on Octahedral Polypyridyl Ruthenium(II) Complexes as Antimicrobial Agents

College of Pharmaceutical Sciences, Southwest University, Chongqing 400715, China
Author to whom correspondence should be addressed.
Received: 1 April 2018 / Revised: 15 May 2018 / Accepted: 7 June 2018 / Published: 10 June 2018
(This article belongs to the Special Issue Antimicrobial Polymers)
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Recent developments of therapeutic agents based on transition metals have attracted a great deal of attention. Metal drugs have advantages over other small molecule drugs, and it was demonstrated that, in a number of studies, they played an important role in pharmaceutical chemical research and clinical chemotherapy of cancers. It is worthwhile mentioning that octahedral polypyridyl ruthenium(II) complexes have shown remarkable applications in chemical biology and medicinal chemistry over the last decade. However, only very recently has there been comprehensive interest in their antimicrobial properties due to metal-related toxic concerns or neglected potential roles in microbiological systems. Our review will highlight the recent developments in octahedral polypyridyl ruthenium(III) complexes that have exhibited significant antimicrobial activities and will discuss the relationship between the chemical structure and biological process of ruthenium complexes, in both bacterial and fungal cells. View Full-Text
Keywords: polypyridyl; octahedral; ruthenium complex; antimicrobial activities polypyridyl; octahedral; ruthenium complex; antimicrobial activities

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This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited (CC BY 4.0).

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Yang, Y.; Liao, G.; Fu, C. Recent Advances on Octahedral Polypyridyl Ruthenium(II) Complexes as Antimicrobial Agents. Polymers 2018, 10, 650.

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