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Polymers 2018, 10(11), 1229; https://doi.org/10.3390/polym10111229

Translocation of Charged Polymers through a Nanopore in Monovalent and Divalent Salt Solutions: A Scaling Study Exploring over the Entire Driving Force Regimes

1
Department of Engineering and System Science, National Tsing Hua University, Hsinchu 30013, Taiwan
2
Institute of Nuclear Engineering and Science, National Tsing Hua University, Hsinchu 30013, Taiwan
Received: 17 October 2018 / Revised: 31 October 2018 / Accepted: 2 November 2018 / Published: 6 November 2018
(This article belongs to the Special Issue Polymer Translocation)
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Abstract

Langevin dynamics simulations are performed to study polyelectrolytes driven through a nanopore in monovalent and divalent salt solutions. The driving electric field E is applied inside the pore, and the strength is varied to cover the four characteristic force regimes depicted by a rederived scaling theory, namely the unbiased (UB) regime, the weakly-driven (WD) regime, the strongly-driven trumpet (SD(T)) regime and the strongly-driven isoflux (SD(I)) regime. By changing the chain length N, the mean translocation time is studied under the scaling form τ N α E δ . The exponents α and δ are calculated in each force regime for the two studied salt cases. Both of them are found to vary with E and N and, hence, are not universal in the parameter’s space. We further investigate the diffusion behavior of translocation. The subdiffusion exponent γ p is extracted. The three essential exponents ν s , q, z p are then obtained from the simulations. Together with γ p , the validness of the scaling theory is verified. Through a comparison with experiments, the location of a usual experimental condition on the scaling plot is pinpointed. View Full-Text
Keywords: polyelectrolyte; translocation; scaling theory; tension propagation; drift-diffusion; molecular dynamics simulations polyelectrolyte; translocation; scaling theory; tension propagation; drift-diffusion; molecular dynamics simulations
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Hsiao, P.-Y. Translocation of Charged Polymers through a Nanopore in Monovalent and Divalent Salt Solutions: A Scaling Study Exploring over the Entire Driving Force Regimes. Polymers 2018, 10, 1229.

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