Table of Contents
Cancers, Volume 9, Issue 1 (January 2017)
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Cover Story (view full-size image) Current biomarkers often require invasive excision of the tumour for profiling, do not allow [...] Read more. Current biomarkers often require invasive excision of the tumour for profiling, do not allow monitoring of the response to treatment and stratify patients into broad heterogeneous groups. Here, we explore and describe the benefits of using circulating nucleosomes and/or modifications to nucleosomes as biomarkers which allow a non‐invasive method for detecting cancer and monitoring response to treatment. We summarize the literature and discuss the potential of circulating nucleosomes as prognostic or diagnostic biomarkers in breast cancer. Circulating nucleosomes as biomarkers are an exciting new method that promises to allow both the early detection of cancer, and monitoring of treatment response. View this paper