Lab-on-a-Chip Technologies for Microgravity Simulation and Space Applications
Abstract
:1. Introduction
2. Lab-on-a-Chip Technologies in Conventional Simulated Microgravity Environment
2.1. Clinostat
2.2. Rotating Wall Vessels
2.3. Random Positioning Machine
2.4. Diamagnetic Levitation
3. CubeSat
4. Plausible Laboratory-Based Microgravity Simulators
5. Summary and Conclusions
Author Contributions
Funding
Data Availability Statement
Acknowledgments
Conflicts of Interest
References
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Type | Features | Simulation Technique | Microgravity Quality | Microgravity Duration | |
---|---|---|---|---|---|
Clinostat | Cuvette/Pipette | Shape—Cylinder | Rotation | ≤10−3 g | Hours to Weeks |
Diameter—3.5 mm | |||||
Slide Flask | Shape—Rectangle | ||||
Width—9 cm | |||||
Length—9 cm | |||||
Submersed | Shape—Cylinder | ||||
Diameter—4.1 mm | |||||
PMT | Shape—Cylinder | ||||
Diameter—4 mm | |||||
Length—5 cm | |||||
Microscope | Shape—Cylinder | ||||
Diameter—30 mm | |||||
RWV | STLV | Shape—Cylinder | Rotation | ≤10−3 g | Hours to Weeks |
Diameter—9.5 cm | |||||
Length—9.6 cm | |||||
HARV | Shape—Cylinder | ||||
Diameter—12.7 cm | |||||
Length—0.64 cm | |||||
RWPV | Shape—Cylinder | ||||
Diameter—5 cm | |||||
Length—7 cm | |||||
RPM | Desktop RPM | Shape—Cubic | Rotation | 10−4 g | Hours to Weeks |
RPI | |||||
MGI | |||||
Diamagnetic Levitation | Bitter Magnet | Features can vary according to the experiment | Magnetic Force | <10−2 g | Minutes to Hours |
Superconducting Magnet | |||||
Permanent Magnet | |||||
CubeSat | GeneSat-1 | CubeSat Size—3U | 10−6 g | 21 days | |
Payload Size—2U | |||||
Weight—6.8 kg | |||||
PharmaSat | CubeSat Size—3U | >21 days | |||
Payload Size—2U | |||||
Weight—5.5 kg | |||||
O/OREOS | CubeSat Size—3U | 6 months | |||
Payload Size—1U | |||||
Weight—5.5 kg | |||||
SporeSat | CubeSat Size—3U | Not Given | |||
Payload Size—2U | |||||
Weight—5.5kg | |||||
EcAMSat | CubeSat Size—6U | >120 days | |||
Payload Size—3U | |||||
Weight—14 kg | |||||
BioSentinel | CubeSat Size—6U | 6–12 months | |||
Payload Size—4U | |||||
Weight—14 kg |
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Vashi, A.; Sreejith, K.R.; Nguyen, N.-T. Lab-on-a-Chip Technologies for Microgravity Simulation and Space Applications. Micromachines 2023, 14, 116. https://doi.org/10.3390/mi14010116
Vashi A, Sreejith KR, Nguyen N-T. Lab-on-a-Chip Technologies for Microgravity Simulation and Space Applications. Micromachines. 2023; 14(1):116. https://doi.org/10.3390/mi14010116
Chicago/Turabian StyleVashi, Aditya, Kamalalayam Rajan Sreejith, and Nam-Trung Nguyen. 2023. "Lab-on-a-Chip Technologies for Microgravity Simulation and Space Applications" Micromachines 14, no. 1: 116. https://doi.org/10.3390/mi14010116