Next Article in Journal
Influence of Botulinum Toxin Therapy on Postural Control and Lower Limb Intersegmental Coordination in Children with Spastic Cerebral Palsy
Previous Article in Journal
Tetanus: Pathophysiology, Treatment, and the Possibility of Using Botulinum Toxin against Tetanus-Induced Rigidity and Spasms
Previous Article in Special Issue
Ochratoxin A Management in Vineyards by Lobesia botrana Biocontrol
Open AccessArticle

First Evidence of Placental Transfer of Ochratoxin A in Horses

Institute of Sciences of Food Production (ISPA), National Council of Research (CNR), Via Amendola 122/O, Bari 70125, Italy
Veterinary Clinic and Animal Productions Unit, Department of Emergency and Organ Transplantation, University of Bari, Strada Provinciale per Casamassima Km 3, Valenzano, Bari 70010, Italy
Author to whom correspondence should be addressed.
Toxins 2013, 5(1), 84-92;
Received: 17 October 2012 / Revised: 28 December 2012 / Accepted: 4 January 2013 / Published: 11 January 2013
(This article belongs to the Special Issue Ochratoxins 2011-2012)
Ochratoxin A (OTA) is a renal mycotoxin and transplacental genotoxic carcinogen. The aim of this study was to evaluate the natural occurrence of OTA in equine blood samples and its placental transfer. For the assessment of OTA levels, serum samples were collected from 12 stallions, 7 cycling mares and 17 pregnant mares. OTA was found in 83% of serum samples (median value = 121.4 pg/mL). For the assessment of placental transfer, serum samples were collected from the 17 mares after delivery and from the umbilical cords of their foals, after foaling. Fourteen serum samples from pregnant mares contained OTA (median value = 106.5 pg/mL), but only 50% of their foals were exposed (median values = 96.6 pg/mL). HPLC analysis carried out on four serum samples (collected from two mares and their respective foals) supported the ELISA results on OTA placental transfer. This is the first report on the natural occurrence of OTA in horse serum samples and placental transfer in horses. View Full-Text
Keywords: serum; ochratoxin A; mycotoxin; placental transfer; horse serum; ochratoxin A; mycotoxin; placental transfer; horse
Show Figures

Figure 1

MDPI and ACS Style

Minervini, F.; Giannoccaro, A.; Nicassio, M.; Panzarini, G.; Lacalandra, G.M. First Evidence of Placental Transfer of Ochratoxin A in Horses. Toxins 2013, 5, 84-92.

Show more citation formats Show less citations formats

Article Access Map by Country/Region

Only visits after 24 November 2015 are recorded.
Search more from Scilit
Back to TopTop