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Clinics and Practice
Volume 7
Issue 4
10.4081/cp.2017.987
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Clinics and Practice is published by MDPI from Volume 11 Issue 1 (2021). Previous articles were published by another publisher in Open Access under a CC-BY (or CC-BY-NC-ND) licence, and they are hosted by MDPI on mdpi.com as a courtesy and upon agreement with PAGEPress.
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Brief Report

Gut Microbiota’s Effect on Mental Health: The Gut-Brain Axis

by
Megan Clapp
1,*,
Nadia Aurora
1,
Lindsey Herrera
1,
Manisha Bhatia
1,
Emily Wilen
1 and
Sarah Wakefield
2
1
School of Medicine, Health Sciences Center, Texas Tech University, TX, USA
2
Department of Psychiatry, Health Sciences Center, Texas Tech University, TX, USA
*
Author to whom correspondence should be addressed.
Clin. Pract. 2017, 7(4), 987; https://doi.org/10.4081/cp.2017.987
Submission received: 9 June 2017 / Revised: 15 August 2017 / Accepted: 21 August 2017 / Published: 15 September 2017
Versions Notes

Abstract

The bidirectional communication between the central nervous system and gut microbiota, referred to as the gut-brain-axis, has been of significant interest in recent years. Increasing evidence has associated gut microbiota to both gastrointestinal and extragastrointestinal diseases. Dysbiosis and inflammation of the gut have been linked to causing several mental illnesses including anxiety and depression, which are prevalent in society today. Probiotics have the ability to restore normal microbial balance, and therefore have a potential role in the treatment and prevention of anxiety and depression. This review aims to discuss the development of the gut microbiota, the linkage of dysbiosis to anxiety and depression, and possible applications of probiotics to reduce symptoms.
Keywords: microbiome; depression; anxiety; gut-brain-axis; dysbiosis microbiome; depression; anxiety; gut-brain-axis; dysbiosis

Share and Cite

MDPI and ACS Style

Clapp, M.; Aurora, N.; Herrera, L.; Bhatia, M.; Wilen, E.; Wakefield, S. Gut Microbiota’s Effect on Mental Health: The Gut-Brain Axis. Clin. Pract. 2017, 7, 987. https://doi.org/10.4081/cp.2017.987

AMA Style

Clapp M, Aurora N, Herrera L, Bhatia M, Wilen E, Wakefield S. Gut Microbiota’s Effect on Mental Health: The Gut-Brain Axis. Clinics and Practice. 2017; 7(4):987. https://doi.org/10.4081/cp.2017.987

Chicago/Turabian Style

Clapp, Megan, Nadia Aurora, Lindsey Herrera, Manisha Bhatia, Emily Wilen, and Sarah Wakefield. 2017. "Gut Microbiota’s Effect on Mental Health: The Gut-Brain Axis" Clinics and Practice 7, no. 4: 987. https://doi.org/10.4081/cp.2017.987

APA Style

Clapp, M., Aurora, N., Herrera, L., Bhatia, M., Wilen, E., & Wakefield, S. (2017). Gut Microbiota’s Effect on Mental Health: The Gut-Brain Axis. Clinics and Practice, 7(4), 987. https://doi.org/10.4081/cp.2017.987

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