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Clinics and Practice
Volume 2
Issue 4
10.4081/cp.2012.e82
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Clinics and Practice is published by MDPI from Volume 11 Issue 1 (2021). Previous articles were published by another publisher in Open Access under a CC-BY (or CC-BY-NC-ND) licence, and they are hosted by MDPI on mdpi.com as a courtesy and upon agreement with PAGEPress.
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Case Report

Occult Ectopic Adrenocorticotropic Hormone Secretion: Diagnostic Dilemma and Infective Consequence

by
Njideka Momah
* and
Thomas Koroscil
Njideka Momah, Thomas Koroscil Wright State University, Dayton, OH, USA
*
Author to whom correspondence should be addressed.
Clin. Pract. 2012, 2(4), e82; https://doi.org/10.4081/cp.2012.e82
Submission received: 23 May 2012 / Revised: 22 July 2012 / Accepted: 30 August 2012 / Published: 13 November 2012

Abstract

A 42-year-old male presented with polyuria, polydipsia and weight loss. His initial physical exam showed a paucity of cushingoid features. Diagnostic work up was consistent with an ectopic adrenocorticotropic hormone (ACTH) secretion. Imaging studies showed a small anterior mediastinal lesion without additional metabolically active tumors. Fine needle aspiration was consistent with a thymic neuroendocrine tumor. Following radical thymectomy, plasma ACTH and cortisol levels remained elevated. Despite medical management, he died within 2 months of presentation of disseminated intracranial aspergillosis. This case underscores the diagnostic dilemma of occult ectopic ACTH-secreting tumors and the fatal consequence of opportunistic infections.
Keywords: thymic carcinoma; aspergillosis; occult adrenocorticotropic hormone secretion thymic carcinoma; aspergillosis; occult adrenocorticotropic hormone secretion

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MDPI and ACS Style

Momah, N.; Koroscil, T. Occult Ectopic Adrenocorticotropic Hormone Secretion: Diagnostic Dilemma and Infective Consequence. Clin. Pract. 2012, 2, e82. https://doi.org/10.4081/cp.2012.e82

AMA Style

Momah N, Koroscil T. Occult Ectopic Adrenocorticotropic Hormone Secretion: Diagnostic Dilemma and Infective Consequence. Clinics and Practice. 2012; 2(4):e82. https://doi.org/10.4081/cp.2012.e82

Chicago/Turabian Style

Momah, Njideka, and Thomas Koroscil. 2012. "Occult Ectopic Adrenocorticotropic Hormone Secretion: Diagnostic Dilemma and Infective Consequence" Clinics and Practice 2, no. 4: e82. https://doi.org/10.4081/cp.2012.e82

APA Style

Momah, N., & Koroscil, T. (2012). Occult Ectopic Adrenocorticotropic Hormone Secretion: Diagnostic Dilemma and Infective Consequence. Clinics and Practice, 2(4), e82. https://doi.org/10.4081/cp.2012.e82

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