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Clinics and Practice, Volume 15, Issue 4

2025 April - 15 articles

Cover Story: We recruited 652 patients, admitted to the hospital for acute coronary syndrome, that were considered eligible if undergoing immediate coronary revascularization procedures for ST-segment-elevation myocardial infarction or coronary revascularization procedures within 24 h. Baseline pulse wave velocity appeared to be the most predictive variable overall, followed by the occurrence of left ventricular hypertrophy and left ventricular end-diastolic diameters. We found that the potential of machine learning to predict life-threatening events is significant. Machine learning algorithms can be used to create models to identify patients at risk for acute myocardial infarction. However, great care must be taken with data quality and ethical use of these algorithms. View this paper
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Articles (15)

  • Systematic Review
  • Open Access
1,938 Views
12 Pages

A Quantitative Systematic Review on the Analgesic Efficacy and Adverse Effects of Ketorolac in Third Molar Surgery

  • Mario Alberto Isiordia-Espinoza,
  • Othoniel Hugo Aragon-Martinez,
  • Nicolás Addiel Serafín-Higuera,
  • Sandra López-Verdín,
  • Eduardo Gómez-Sánchez,
  • Nelly Molina-Frechero,
  • Ronell Bologna-Molina,
  • Juan Manuel Guzmán-Flores and
  • Itzel Joselyn Mora-Falcón

Objectives: This study aimed to determine the number needed to treat (NNT) of ketorolac in comparison to placebo after third molar surgery. Methods: Studies located in PubMed, Scopus, and Web of Science were evaluated with the Cochrane Risk of Bias a...

  • Review
  • Open Access
3 Citations
1,484 Views
21 Pages

An Overview of the Etiopathogenic Mechanisms Involved in the Expression of the Oral Microbiota

  • Ion Alexandru Popovici,
  • Cristian Ionut Orasanu,
  • Georgeta-Camelia Cozaru,
  • Anita-Cristina Ionescu,
  • Lidia Kajanto,
  • Bogdan Cimpineanu,
  • Anca Chisoi,
  • Adrian Nelutu Mitroi,
  • Ionut Poinareanu and
  • Mihaela Butcaru Pundiche
  • + 2 authors

Background/Objectives: The diversity of the oral microbiota exerts its effects in maintaining dental and overall health. The unique genetic profile of each individual influences the composition of the oral microbiota, determining susceptibility to ce...

  • Systematic Review
  • Open Access
2 Citations
3,436 Views
13 Pages

Factors Influencing Adherence to Non-Invasive Telemedicine in Heart Failure: A Systematic Review

  • George Koulaouzidis,
  • Lamprini Tsigkriki,
  • Orestis Grammenos,
  • Sotiria Iliopoulou,
  • Maria Kalaitzoglou,
  • Panagiotis Theodorou,
  • Ioannis Bostanitis,
  • Karolina Skonieczna-Żydecka and
  • Dafni Charisopoulou

Background/Objectives: Telemedicine (TM) has emerged as a promising tool for improving heart failure (HF) management by allowing non-invasive, remote patient monitoring. However, patient adherence to TM plays a critical role in its effectiveness. Thi...

  • Article
  • Open Access
1,679 Views
21 Pages

Background: Chronic diseases require long-term and multidimensional care, but traditional medical education has emphasised acute care and episodic interventions. This gap limits the understanding of future clinicians about the complexity of managing...

  • Review
  • Open Access
11 Citations
3,438 Views
12 Pages

Cutaneous leishmaniasis (CL) is a vector-borne infection caused by protozoan parasites belonging to the genus Leishmania. CL is an emerging global health concern due to increasing migration, travel, and climate change. Traditionally, it was confined...

  • Article
  • Open Access
4 Citations
4,336 Views
16 Pages

A Cohort Study on the Impact of Oral Health on the Quality of Life of Adolescents and Young Adults

  • Iva Klarić Puđa,
  • Kristina Goršeta,
  • Hrvoje Jurić,
  • Mirko Soldo,
  • Luc A. M. Marks and
  • Martina Majstorović

Objectives: This cohort study examines the relationship between quality of life and oral health in adolescents and young adults in the Zagreb area. Methods: The research involved 250 participants aged 14 to 25 from Zagreb. Each participant was examin...

  • Case Report
  • Open Access
1,503 Views
8 Pages

Clear Cell Renal Carcinoma in an Ulcerative Colitis Patient Under Short-Term Immunosuppressive Therapy: A Case Report

  • Raffaele Pellegrino,
  • Giuseppe Imperio,
  • Michele Izzo,
  • Ilaria De Costanzo,
  • Fabio Landa,
  • Paola Ciamarra,
  • Marco Niosi,
  • Antonietta Gerarda Gravina and
  • Alessandro Federico

Background/Objectives: Renal cell cancer is a rare occurrence in patients with ulcerative colitis (UC), with no clearly demonstrated association between UC and an increased risk of renal malignancies. In this article, a case report concerning this re...

  • Review
  • Open Access
9 Citations
3,131 Views
8 Pages

Neuron-Specific Enolase and S100B as Biomarkers of Ischemic Brain Injury During Surgery

  • Matej Makovec,
  • Milan Skitek,
  • Leja Šimnovec and
  • Aleš Jerin

Biochemical markers can be used in addition to neuroimaging techniques to evaluate the extent of ischemic brain injuries and to enable earlier diagnosis and faster intervention following the ischemic event. Among the potential biomarkers of ischemic...

  • Article
  • Open Access
2,239 Views
19 Pages

Effect of Continuous Positive Airway Pressure (CPAP) Mode on Lung Function, Exercise Tolerance, Vital Signs, and Dyspnea After Acute SARS-CoV-2 Infection

  • Emilia Raposo Nascimento,
  • Paloma Lopes Francisco Parazzi,
  • Fernando Augusto Lima Marson,
  • Maria Ângela Gonçalves Oliveira Ribeiro,
  • Carla Cristina Sousa Gomez,
  • Patrícia Blau Margosian Conti,
  • Bianca Aparecida Siqueira,
  • Edvane Aparecida Braz Araújo Silva and
  • José Dirceu Ribeiro

Background/Objectives: The coronavirus disease (COVID-19) pandemic was associated with an intense impact on health worldwide. Among the sequelae, it became necessary to clarify respiratory impairment related to lung function and aerobic capacity, as...

  • Article
  • Open Access
3 Citations
1,259 Views
12 Pages

Predictors of Acute Myocardial Infarction: A Machine Learning Analysis After a 7-Year Follow-Up

  • Marco Casciaro,
  • Pierpaolo Di Micco,
  • Alessandro Tonacci,
  • Marco Vatrano,
  • Vincenzo Russo,
  • Carmine Siniscalchi,
  • Sebastiano Gangemi and
  • Egidio Imbalzano

Background: Ischemic heart disease is a major global health problem with significant morbidity and mortality. Several cardiometabolic variables play a key role in the incidence of adverse cardiovascular outcomes. Objectives: The aim of the present st...

  • Case Report
  • Open Access
2,314 Views
11 Pages

Introduction: About one in four people show an immunological reaction to an infection with Mycobacterium tuberculosis, which can remain latent or lead to active forms of the disease. Psoriasis is a chronic, immune-mediated skin disease that can be as...

  • Case Report
  • Open Access
2 Citations
6,523 Views
13 Pages

Background: Streptococcal toxic shock syndrome (STSS) is a serious and potentially fatal complication of invasive Streptococcus pyogenes (Group A Streptococcus, GAS) infection, often stemming from severe soft tissue infections. While uncommon, tonsil...

  • Article
  • Open Access
2,568 Views
11 Pages

Changes in Perceived Tinnitus Sound Qualities Following Internet-Based Cognitive Behavioral Therapy for Tinnitus

  • Vinaya Manchaiah,
  • Gerhard Andersson,
  • Eldré W. Beukes,
  • Marc A. Fagelson,
  • De Wet Swanepoel and
  • David Maidment

Background: To examine the changes in perceived tinnitus sound qualities following internet-based cognitive behavioral therapy (ICBT) for tinnitus. Method: This study was embedded within several clinical trials evaluating the efficacy of ICBT and use...

  • Systematic Review
  • Open Access
4,632 Views
21 Pages

The Effect of Pregnancy on Dermatological Disorders: A Systematic Review

  • Maya Faissal Alhomieed,
  • Lara Osama Al Hartany,
  • Marya Aref Alghorab,
  • Arwa Alsharif,
  • Ahlam Kaleemullah,
  • Hanan Ismail Wasaya,
  • Khlood Abdulaziz Alsubaie,
  • Ayah Nabil Al Jehani,
  • Amal Mohamed Kayali and
  • Samera AlBasri

Background: Pregnancy induces hormonal, immunologic, and vascular changes that profoundly affect dermatologic health. This systematic review aimed to assess the impact of pregnancy on dermatological disorders in terms of disease incidence, severity,...

  • Article
  • Open Access
1 Citations
3,687 Views
12 Pages

Renal Trauma: A 4-Year Retrospective Review of Injury Severity, Treatment Approaches, and Outcomes from a Polish Trauma Center

  • Michał Kasperczak,
  • Anita Zaręba,
  • Karolina Pawłowska-Kasperczak,
  • Filip Kasperczak,
  • Monika Zaręba and
  • Andrzej Antczak

Background: The management of renal injuries in hemodynamically stable adult patients is moving toward more conservative methods, even in cases of severe grade and/or penetrating trauma. The objective of this study was to analyze the patterns of inju...

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Clin. Pract. - ISSN 2039-7283