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Nursing Reports
Volume 5
Issue 1
10.4081/nursrep.2015.5218
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Nursing Reports is published by MDPI from Volume 10 Issue 1 (2020). Previous articles were published by another publisher in Open Access under a CC-BY (or CC-BY-NC-ND) licence, and they are hosted by MDPI on mdpi.com as a courtesy and upon agreement with PAGEPress.
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Background:
Brief Report

Be sweet to toddlers during needles: pilot randomized controlled trial of sucrose compared to placebo

by
Denise Harrison
1,*,
Jessica Reszel
2,
Nick Barrowman
2,
Brenda Martelli
3,
Diane Sharp
4 and
Regis Vailancourt
5
1
Denise Harrison, 401 Smyth Road, Ottawa ON, K1H 8L1, Canada
2
Children’s Hospital of Eastern Ontario Research Institute, Ottawa, Canada
3
Integrated Pain Services, Children’s Hospital of Eastern Ontario, Ottawa, Canada
4
Corporate Patient Services, Children’s Hospital of Eastern Ontario, Ottawa, Canada
5
Pharmacy, Children’s Hospital of Eastern Ontario, Ottawa, Canada
*
Author to whom correspondence should be addressed.
Nurs. Rep. 2015, 5(1), 5218; https://doi.org/10.4081/nursrep.2015.5218
Submission received: 6 April 2015 / Revised: 6 May 2015 / Accepted: 7 May 2015 / Published: 9 June 2015
Versions Notes

Abstract

Sweet solutions reduce procedural pain in infants but there is uncertainty about effectiveness beyond infancy. A blinded pilot randomized controlled trial (RCT) was conducted to inform a full-scale RCT. Hospitalized children aged 12- 36 months were randomized to 24% sucrose or water prior to and during venipuncture. Primary outcomes were crying time and FLACC (Face, Legs, Activity, Cry, Consolability) scores. Secondary outcomes parental report of child’s pain, parental perception of effectiveness and nurse’s score of child’s compliance with study solution. Twenty-one children were studied. There were no differences in pain outcomes between groups. Median FLACC scores at time of needle insertion were high (8/10), and mean crying time during procedure was 61%. Most parents (n=17) would use the same treatment next time and most (n=17) toddlers were compliant with receiving the solutions. The pilot RCT informed the conduct of a future full scale RCT in terms of feasibility, acceptability, data collection, data analysis and sample size estimation.
Keywords: Pain; painful; children; sucrose; venipuncture Pain; painful; children; sucrose; venipuncture

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MDPI and ACS Style

Harrison, D.; Reszel, J.; Barrowman, N.; Martelli, B.; Sharp, D.; Vailancourt, R. Be sweet to toddlers during needles: pilot randomized controlled trial of sucrose compared to placebo. Nurs. Rep. 2015, 5, 5218. https://doi.org/10.4081/nursrep.2015.5218

AMA Style

Harrison D, Reszel J, Barrowman N, Martelli B, Sharp D, Vailancourt R. Be sweet to toddlers during needles: pilot randomized controlled trial of sucrose compared to placebo. Nursing Reports. 2015; 5(1):5218. https://doi.org/10.4081/nursrep.2015.5218

Chicago/Turabian Style

Harrison, Denise, Jessica Reszel, Nick Barrowman, Brenda Martelli, Diane Sharp, and Regis Vailancourt. 2015. "Be sweet to toddlers during needles: pilot randomized controlled trial of sucrose compared to placebo" Nursing Reports 5, no. 1: 5218. https://doi.org/10.4081/nursrep.2015.5218

APA Style

Harrison, D., Reszel, J., Barrowman, N., Martelli, B., Sharp, D., & Vailancourt, R. (2015). Be sweet to toddlers during needles: pilot randomized controlled trial of sucrose compared to placebo. Nursing Reports, 5(1), 5218. https://doi.org/10.4081/nursrep.2015.5218

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