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Thalassemia Reports, Volume 14, Issue 3

2024 September - 3 articles

Cover Story: β-thalassemia, a life-threatening inheritable hemoglobin disorder caused by mutations in the HBB gene, poses a significant public health challenge in the world. Although no comprehensive work has been carried out in Bangladesh, the world prevalence and small-scale works have indicated the possibility of a high prevalence of this disease in the country. Therefore, this review aims to explore the present situation of β-thalassemia in Bangladesh and propose approaches to mitigate its impact in the future. Limited awareness, a high incidence of consanguineous marriage, and inadequate access to healthcare are the possible factors responsible for the high prevalence of thalassemia in Bangladesh, while the absence of public health policy and a national health insurance system further exacerbate the situation. View this paper

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Article

1 Citations

3,207 Views

10 Pages

The Effect of Resveratrol on Gamma Globin Gene Expression in Patients with Beta Thalassemia: The Role of Adaptation to Cellular Stress

Hossein Jalali,
Mohammad Reza Mahdavi,
Mehrnoush Kosaryan,
Ahmad Najafi and ,
Aily Aliasgharian and
Ebrahim Salehifar
+ 1 author+ 0 author

Thalass. Rep.2024, 14(3), 71-80;https://doi.org/10.3390/thalassrep14030009

17 September 2024

HbF induction is an appropriate strategy to ameliorate the severity of β-thalassemia symptoms. Hydroxyurea (HU) is the most common chemical agent introduced as an HbF inducer but responsiveness to HU is variable and the introduction of HbF induc...

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Article

2 Citations

3,921 Views

11 Pages

Sociodemographic Determinants of Adherence and Treatment Efficacy in Paediatric Thalassemia Patients from Sarbaz-Rask, Iran

Atousa Babamohammadi,
QiYuee Wang,
Elham Mohajeri and
Saeid Esmaeilian

Thalass. Rep.2024, 14(3), 60-70;https://doi.org/10.3390/thalassrep14030008

15 August 2024

Background: The effective management of iron overload in transfusion-dependent thalassemia (TDT) requires adherence to iron chelation therapy (ICT). However, adherence rates among pediatric thalassemia patients remain suboptimal. This study aimed to...

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Review

3 Citations

11,156 Views

11 Pages

β-Thalassemia in Bangladesh: Current Status and Future Perspectives

Arnob Mitro,
Didar Hossain,
Md Muhibur Rahman,
Beauty Dam and
Mohammad Jakir Hosen

Thalass. Rep.2024, 14(3), 49-59;https://doi.org/10.3390/thalassrep14030007

8 July 2024

β-thalassemia, a life-threatening inheritable hemoglobin disorder caused by mutations in the HBB gene, poses a significant public health challenge in the world. Although no comprehensive work has been carried out in Bangladesh, the world prevale...

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Thalass. Rep. - ISSN 2039-4365

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