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Hematology Reports
Volume 13
Issue 2
10.4081/hr.2021.8967
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Hematology Reports is published by MDPI from Volume 14 Issue 1 (2022). Previous articles were published by another publisher in Open Access under a CC-BY (or CC-BY-NC-ND) licence, and they are hosted by MDPI on mdpi.com as a courtesy and upon agreement with PAGEPress.
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Article

The Risk of Venipuncture in Newborn with Severe Hemophilia: Case Report of a Large Elbow Hemorrhage and Literature Review of Compartment Syndrome

by
Giuseppe Lassandro
,
Anna Amoruso
,
Valentina Palladino
,
Viviana Valeria Palmieri
and
Paola Giordano
*
Pediatric Section, Department of Biomedical Science and Human Oncology, University “Aldo Moro”, Piazza Giulio Cesare 11, 70124 Bari, Italy
*
Author to whom correspondence should be addressed.
Hematol. Rep. 2021, 13(2), 8967; https://doi.org/10.4081/hr.2021.8967
Submission received: 26 September 2020 / Revised: 11 December 2020 / Accepted: 26 February 2021 / Published: 9 June 2021

Abstract

Hemophilias are hemorrhagic congenital rare diseases. The gold standard of therapy in hemophilics is the intravenously replacement therapy. We can infuse intravenously plasma derived factors (FVIII for Hemophilia A and FIX for Hemophilia B) or recombinant products (i.e., clotting factor synthetically produced). Venipuncture is not a safe procedure in subjects with hemorrhagic diseases. It is considered an invasive technique with potential massive bleeding and it requires standardized procedures to prevent complications. Local pressure after the procedure (with eventually ice rest) must be always done. In case of bleeding a rapid replacement therapy must be conducted. A severe complication in hemophilia is compartment syndrome. We report a case of massive bleeding in a hemophilic newborn after venipuncture and a literature review of compartment syndrome in hemophiliacs. The aim of this paper is to help physicians in the clinical management to prevent the evolution of a massive bleeding in compartment syndrome.
Keywords: newborn, hemophilia, venipuncture, bleeding, compartment syndrome newborn, hemophilia, venipuncture, bleeding, compartment syndrome

Share and Cite

MDPI and ACS Style

Lassandro, G.; Amoruso, A.; Palladino, V.; Palmieri, V.V.; Giordano, P. The Risk of Venipuncture in Newborn with Severe Hemophilia: Case Report of a Large Elbow Hemorrhage and Literature Review of Compartment Syndrome. Hematol. Rep. 2021, 13, 8967. https://doi.org/10.4081/hr.2021.8967

AMA Style

Lassandro G, Amoruso A, Palladino V, Palmieri VV, Giordano P. The Risk of Venipuncture in Newborn with Severe Hemophilia: Case Report of a Large Elbow Hemorrhage and Literature Review of Compartment Syndrome. Hematology Reports. 2021; 13(2):8967. https://doi.org/10.4081/hr.2021.8967

Chicago/Turabian Style

Lassandro, Giuseppe, Anna Amoruso, Valentina Palladino, Viviana Valeria Palmieri, and Paola Giordano. 2021. "The Risk of Venipuncture in Newborn with Severe Hemophilia: Case Report of a Large Elbow Hemorrhage and Literature Review of Compartment Syndrome" Hematology Reports 13, no. 2: 8967. https://doi.org/10.4081/hr.2021.8967

APA Style

Lassandro, G., Amoruso, A., Palladino, V., Palmieri, V. V., & Giordano, P. (2021). The Risk of Venipuncture in Newborn with Severe Hemophilia: Case Report of a Large Elbow Hemorrhage and Literature Review of Compartment Syndrome. Hematology Reports, 13(2), 8967. https://doi.org/10.4081/hr.2021.8967

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