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Infectious Disease Reports, Volume 16, Issue 6

2024 December - 19 articles

Cover Story: Fungal and bacterial infections are a common cause of skin diseases. In a cohort of 6086 dermatology outpatients, we utilized a multiplexed PCR assay for the simultaneous detection of fungal and bacterial pathogens, offering improved sensitivity and a faster turnaround time than conventional methods. This methodology allowed us to detect and identify patient risk factors for dermatophytes, Malassezia, Candida, and Staphylococcus aureus. Furthermore, this assay detects the mecA gene conferring β-lactam resistance, as recent studies have reported evidence of MRSA in the dermatology outpatient population. In cases of mixed bacterial and fungal infections, preliminary evidence has shown that dermatophytes can produce penicillin-like antibiotics in vitro, raising the possibility of MRSA selection in cases of concomitant S. aureus colonization. View this paper
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Articles (19)

  • Case Report
  • Open Access
3 Citations
2,851 Views
11 Pages

Fulminant Invasive Aspergillosis in a Previously Healthy Woman After Cesarean Section and a Review of the Literature

  • Luca Pipitò,
  • Gennaro Baldino,
  • Giovanni Bartoloni,
  • Maurizio Sanguinetti,
  • Elvira Ventura Spagnolo and
  • Antonio Cascio

20 December 2024

Background: Invasive aspergillosis is an extremely rare condition in healthy and immunocompetent individuals, and very few cases have been reported in previously healthy, pregnant, or postpartum women. Method: We describe a case of invasive aspergill...

  • Article
  • Open Access
1,546 Views
9 Pages

Role of Multimodal Imaging in Clinical Practice for the Diagnosis of Infective Endocarditis: A Case Series

  • Sara Tordi,
  • Giacomo Gonnelli,
  • Maria Carolina Benvenuto,
  • Daniele Rosignoli,
  • Lisa Malincarne and
  • Daniela Francisci

17 December 2024

Background: The 2023 European Society of Cardiology (ESC) guidelines for the management of infective endocarditis (IE) highlighted the essential role of multimodal imaging in the diagnostic algorithm of IE and its complications. Methods: We hereby re...

  • Article
  • Open Access
2 Citations
2,034 Views
14 Pages

Infection Rate and Risk Factors of SARS-CoV-2 Infection in Retail Workers at the Onset of the COVID-19 Pandemic, Quebec, Canada

  • Kim Santerre,
  • Mathieu Thériault,
  • Nicholas Brousseau,
  • Marc-André Langlois,
  • Corey Arnold,
  • Joelle N. Pelletier,
  • Caroline Gilbert,
  • Jean-François Masson,
  • Mariana Baz and
  • Sylvie Trottier
  • + 1 author

16 December 2024

Background/Objectives: During the pandemic, client-facing workers were perceived to be at greater risk of SARS-CoV-2 infection. This study investigated the risk factors for SARS-CoV-2 infection among a cohort of 304 retail workers in the Quebec City...

  • Case Report
  • Open Access
2,104 Views
10 Pages

16 December 2024

Background/Objectives: Common Variable Immunodeficiency Disease (CVID) and other immunodeficiencies can present in subtle and variable ways. Whether or not a genetic lesion can be identified, there are not well understood biomarkers that quantitative...

  • Article
  • Open Access
8 Citations
2,062 Views
16 Pages

Antibiofilm Activity of Epinecidin-1 and Its Variants Against Drug-Resistant Candida krusei and Candida tropicalis Isolates from Vaginal Candidiasis Patients

  • Sivakumar Jeyarajan,
  • Sukumar Ranjith,
  • Raja Veerapandian,
  • Kalimuthusamy Natarajaseenivasan,
  • Prahalathan Chidambaram and
  • Anbarasu Kumarasamy

12 December 2024

Background/Objective: Indwelling intrauterine contraceptive devices (IUDs) have surfaces that facilitate the attachment of Candida spp., creating a suitable environment for biofilm formation. Due to this, vulvovaginal candidiasis (VVC) is frequently...

  • Article
  • Open Access
3 Citations
2,613 Views
17 Pages

6 December 2024

Background: The global push to eliminate tuberculosis (TB) as a public health threat is increasingly urgent, particularly in high-burden areas like the Oliver Reginald Tambo District Municipality, South Africa. Drug-resistant TB (DR-TB) poses a signi...

  • Case Report
  • Open Access
2 Citations
2,247 Views
6 Pages

The First-Ever Encounter with Salmonella enterica Serovar Hvittingfoss Causing Acute Gastroenteritis in India: A Case Report

  • Mahadevaiah Neelambike Sumana,
  • Morubagal Raghavendra Rao,
  • Deepashree Rajshekar,
  • Krishna Karthik,
  • Nikita K Shah,
  • Veerabhadra Swamy,
  • Chinchana Shylaja Eshwar and
  • Yogeesh D Maheshwarappa

2 December 2024

Background: Salmonella enterica serovar Hvittingfoss, a member of the non-typhoidal Salmonella group, is an important foodborne serovar most frequently identified in regions (Australia, Belgium, and the United States) with active surveillance sy...

  • Case Report
  • Open Access
1 Citations
3,049 Views
9 Pages

Delayed Diagnosis of Disseminated Invasive Aspergillosis with Purulent Myocarditis in an Immunocompromised Host

  • Mark Londema,
  • Maarten W. N. Nijsten,
  • Joost Bart,
  • Janke S. Wiegersma,
  • Bhanu N. M. Sinha and
  • Douwe F. Postma

30 November 2024

Introduction: Invasive aspergillosis (IA) is an opportunistic fungal infection that typically occurs in the immunocompromised host and is associated with severe morbidity and mortality. Myocardial abscess formation is seldomly described. Detailed Cas...

  • Review
  • Open Access
44 Citations
17,203 Views
55 Pages

28 November 2024

Background: Phage therapy, a treatment utilizing bacteriophages to combat bacterial infections, is gaining attention as a promising alternative to antibiotics, particularly for managing antibiotic-resistant bacteria. This study aims to provide a comp...

  • Article
  • Open Access
1 Citations
2,369 Views
9 Pages

Multidisciplinary Approach of a Male Case of Imported Malaria, HIV Chronic Infection, and Latent Syphilis

  • Rebeca Eunice García-Mendiola,
  • Maritza Micheli García-Lucas,
  • Jennifer Morales-Vázquez,
  • Raúl Adrián Cruz-Flores,
  • Miguel Ángel Loyola-Cruz,
  • Clemente Cruz-Cruz,
  • Emilio Mariano Durán-Manuel,
  • Enzo Vásquez-Jiménez,
  • Graciela Castro-Escarpulli and
  • Juan Manuel Bello-López
  • + 10 authors

27 November 2024

Background: The current economic and social crisis in Latin America has caused migration to the USA, bringing with it Public Health challenges due to the importation of various infectious diseases. Migrants, particularly those with chronic conditions...

  • Article
  • Open Access
9,903 Views
10 Pages

The Effectiveness of Topical Treatment for Plantar Warts: A Retrospective Cohort Study

  • Ana Mª Rayo Pérez,
  • José María Juárez Jiménez,
  • Rafael Rayo Rosado and
  • Raquel García de la Peña

26 November 2024

Background: Plantar warts, caused by human papillomavirus (HPV), are a common condition that can be painful and resistant to treatment. There are various therapeutic options for managing them, but it is not always clear which are the most effective a...

  • Article
  • Open Access
1 Citations
1,759 Views
10 Pages

Impact of the COVID-19 Pandemic on the Detection of Leprosy in Micro-Regions with a High Risk of Illness in Minas Gerais, Brazil

  • Sarah Lamas Vidal,
  • Daniele dos Santos Lages,
  • Isabela Cristina Lana Maciel,
  • Isabel Cristina Gonçalves Leite,
  • Angélica da Conceição Oliveira Coelho and
  • Francisco Carlos Félix Lana

26 November 2024

Background: Leprosy control remains challenging in Brazil and has been aggravated by the COVID-19 pandemic. Objective: To analyze the impact of the COVID-19 pandemic on the epidemiological scenario of leprosy through the detection rate of new cases,...

  • Article
  • Open Access
1,114 Views
14 Pages

SARS-CoV-2 Immunization Index in the Academic Community: A Retrospective Post-Vaccination Study

  • Keltyn Oliveira,
  • Ana Almeida,
  • Carina Silva,
  • Miguel Brito and
  • Edna Ribeiro

25 November 2024

Background/Objectives: The COVID-19 pandemic has revolutionized vaccine production and compelled a massive global vaccination campaign. This study aimed to estimate the positivity and levels of SARS-CoV-2 IgG antibodies acquired due to vaccination an...

  • Article
  • Open Access
2 Citations
2,752 Views
9 Pages

Molecular Identification of Etiological Agents in Fungal and Bacterial Skin Infections: United States, 2020–2024

  • Aditya K. Gupta,
  • Tong Wang,
  • Sara A. Lincoln,
  • Hui-Chen Foreman and
  • Wayne L. Bakotic

18 November 2024

Background/Objectives: Cutaneous infections of fungal and bacterial origins are common. An accurate diagnosis—especially concerning pathogens that are difficult to isolate on culture—can be achieved using molecular methods (PCR) with a sh...

  • Case Report
  • Open Access
1 Citations
2,570 Views
11 Pages

Lemierre Syndrome Associated with Streptococcus constellatus and Atypical Vascular Involvement: A Case Report and Review of the Literature

  • Luca Pipitò,
  • Antonio Anastasia,
  • Fabrizio Passalacqua,
  • Giulio D’Agati,
  • Floriana Di Figlia,
  • Benedetta Romanin,
  • Silvia Bonura,
  • Raffaella Rubino,
  • Agostino Inzerillo and
  • Antonio Cascio
  • + 1 author

12 November 2024

Background: Lemierre syndrome is a rare and life-threatening disease. It is characterized by septic thrombophlebitis of the internal jugular vein, historically associated with Fusobacterium necrophorum infection. However, atypical cases and associati...

  • Case Report
  • Open Access
1 Citations
1,975 Views
9 Pages

Legionella pneumophilaKlebsiella pneumoniae Pulmonary Coinfection in a COVID-19 Patient: Case Report

  • Maria Irina Brumboiu,
  • Edina Iuga,
  • Andreea Ivanciuc,
  • Irina Iaru,
  • Alexandru Durla-Pașca,
  • Pavel Șchiopu and
  • Adrian Gabriel Pană

11 November 2024

Background. Pulmonary superinfections increase the mortality risk among COVID-19 patients, highlighting the need for enhanced understanding to enable early and accurate diagnosis. Methods. We present the case of a patient, a 76-year-old man, hospital...

  • Case Report
  • Open Access
2 Citations
3,305 Views
10 Pages

Multidisciplinary Approach in Rare, Fulminant-Progressing, and Life-Threatening Facial Necrotizing Fasciitis

  • Mihaela Pertea,
  • Stefana Luca,
  • Raluca Tatar,
  • Bogdan Huzum,
  • Mihai Ciofu,
  • Vladimir Poroch,
  • Dragos Octavian Palade,
  • Daniela Vrinceanu,
  • Mihail Balan and
  • Oxana Madalina Grosu

1 November 2024

(1) Background: Necrotizing fasciitis is known as a severe condition with a high risk of mortality, placing it among the most feared infections. In most cases, it has a polymicrobial etiology (type 1), requiring complex treatment that is continuously...

  • Article
  • Open Access
1,967 Views
9 Pages

Proprotein Convertase Subtilisin Kexin 9 Inhibitor in Severe Sepsis and Septic Shock Patients in a Phase II Prospective Cohort Study—Preliminary Results

  • Ziv Rosman,
  • Yasmin Maor,
  • Iris Zohar,
  • Gingy Ronen Balmor,
  • Miri Schamroth Pravda,
  • Adam Lee Goldstein,
  • Milena Tocut and
  • Arie Soroksky

24 October 2024

Sepsis is a life-threatening organ dysfunction syndrome caused by a dysregulated host response to infection that has a high mortality rate. Proprotein convertase subtilisin kexin 9 (PCSK9) is a serine protease secreted by the liver. Its binding to th...

  • Case Report
  • Open Access
2,435 Views
6 Pages

Consideration of Antifungal Coverage in Treating Infections Related to Delayed Esophageal Perforation from Anterior Cervical Spine Hardware

  • Kavita Prasad,
  • John Ceremsak,
  • Jean-Nicolas Gallant,
  • Hannah G. Kay,
  • Erin B. Gettler,
  • Benjamin R. Campbell,
  • Catherine R. Carlile,
  • Byron F. Stephens,
  • Sarah L. Rohde and
  • Christina T. Fiske
  • + 1 author

23 October 2024

(1) Background/Objectives: Delayed esophageal perforation following anterior cervical (spine) discectomy and fusion (ACDF) is rare but can lead to serious infectious complications. The treatment usually involves hardware explanation and prolonged int...

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Infect. Dis. Rep. - ISSN 2036-7449