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Infectious Disease Reports, Volume 16, Issue 2

April 2024 - 19 articles

Cover Story: Infectious diseases (IDs) are a leading cause of death. The diversity and adaptability of microbes represent a continuing risk to health.
In this article, we put in context how transdisciplinary research and team diversity were instrumental in changing the practice of medicine to fulfill the unmet needs of patients and health professionals.
Driven by curiosity, audacity, openness and simplicity (CAOS), our group’s integrated approach yielded better management of IDs through regulatory-cleared rapid molecular detection of pathogens and their resistance genes directly from clinical samples. We also discuss innovative infection prevention that has been long neglected.
Winning strategy: Addressing microbial diversity challenges with human diversity to better control IDs. View this paper
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Articles (19)

  • Review
  • Open Access
3 Citations
3,483 Views
27 Pages

18 April 2024

The coronavirus disease 2019 (COVID-19) has left a devasting effect on various regions globally. Africa has exceptionally high rates of other infectious diseases, such as tuberculosis (TB), human immunodeficiency virus (HIV), and malaria, and was not...

  • Article
  • Open Access
9 Citations
5,757 Views
13 Pages

Global Measles Surveillance: Trends, Challenges, and Implications for Public Health Interventions

  • Francesco Branda,
  • Marta Giovanetti,
  • Chiara Romano,
  • Domenico Benvenuto,
  • Alessandra Ciccozzi,
  • Daria Sanna,
  • Massimo Ciccozzi and
  • Fabio Scarpa

16 April 2024

Measles, a highly contagious disease primarily affecting children, carries serious health risks, including complications and mortality. Vaccination remains the most effective preventive measure against measles transmission. The COVID-19 pandemic has...

  • Article
  • Open Access
1 Citations
1,730 Views
11 Pages

Multicenter Study of the Effectiveness of Antifungal Stewardship Team Intervention for Candidemia in Japan in 2008–2021

  • Mieko Tokano,
  • Norihito Tarumoto,
  • Jun Sakai,
  • Kazuo Imai,
  • Sakaru Koizumi,
  • Haruka Karaushi,
  • Tamotsu Hatanaka,
  • Etsuko Kishi,
  • Masafumi Seki and
  • Koutaro Mitsutake
  • + 1 author

15 April 2024

Candidemia, linked to high mortality rates, requires prompt antifungal therapy for better outcomes. Treatment is structured as an action bundle, which is beneficial when followed closely. However, the Japanese action bundle lacks detailed guidance on...

  • Review
  • Open Access
10 Citations
3,311 Views
39 Pages

Respiratory Syncytial Virus Infections in Recipients of Bone Marrow Transplants: A Systematic Review and Meta-Analysis

  • Matteo Riccò,
  • Salvatore Parisi,
  • Silvia Corrado,
  • Federico Marchesi,
  • Marco Bottazzoli and
  • Davide Gori

29 March 2024

Human Respiratory Syncytial Virus (RSV) is a common cause of respiratory tract infections. Usually associated with infants and children, an increasing amount of evidence suggests that RSV can cause substantial morbidity and mortality in immunocomprom...

  • Review
  • Open Access
7 Citations
3,928 Views
19 Pages

Current Progress and Future Perspectives in Contact and Releasing-Type Antimicrobial Coatings of Orthopaedic Implants: A Systematic Review Analysis Emanated from In Vitro and In Vivo Models

  • Angelos Kaspiris,
  • Elias Vasiliadis,
  • Evangelia Pantazaka,
  • Ioanna Lianou,
  • Dimitra Melissaridou,
  • Matthaios Savvidis,
  • Fotios Panagopoulos,
  • Georgios Tsalimas,
  • Michail Vavourakis and
  • Ioannis Kolovos
  • + 2 authors

26 March 2024

Background: Despite the expanding use of orthopedic devices and the application of strict pre- and postoperative protocols, the elimination of postoperative implant-related infections remains a challenge. Objectives: To identify and assess the in vit...

  • Commentary
  • Open Access
1 Citations
1,910 Views
9 Pages

On the SARS-CoV-2 Variants

  • Fabio Scarpa,
  • Francesco Branda,
  • Nicola Petrosillo and
  • Massimo Ciccozzi

26 March 2024

The evolutionary dynamics of viruses, particularly exemplified by SARS-CoV-2 during the ongoing COVID-19 pandemic, underscore the intricate interplay between genetics, host adaptation, and viral spread. This paper delves into the genetic evolution of...

  • Commentary
  • Open Access
5 Citations
2,254 Views
8 Pages

A One Health Platform for Future Epidemic Preparedness

  • Francesco Branda,
  • Fabio Scarpa,
  • Nicola Petrosillo and
  • Massimo Ciccozzi

20 March 2024

Here, we introduce the EpiConnect Intelligence Platform (ECIP), a platform facilitating rapid, transparent data sharing and analysis to support researchers and public health officials in Europe, with a focus on Italy. ECIP provides reliable, concise,...

  • Case Report
  • Open Access
1 Citations
2,348 Views
12 Pages

Whipple Disease Presenting as Isolated Transverse Myelitis with Permanent Neurological Damage in a Patient with Systemic Lupus Erythematosus: A Case Report of a Difficult Diagnosis with a Literature Review

  • Carolina Saffioti,
  • Marta Nebiolo,
  • Roberta Caorsi,
  • Alessio Mesini,
  • Mariasavina Severino,
  • Giacomo Brisca,
  • Elio Castagnola and
  • Marco Gattorno

19 March 2024

We describe an atypical case of Whipple disease exclusively involving the spinal cord in an adolescent receiving immunosuppressive therapy for systemic lupus erythematosus. The diagnosis was particularly difficult since lupus and Whipple disease can...

  • Brief Report
  • Open Access
1,437 Views
9 Pages

A Vulnerability Index to Assess the Risk of SARS-CoV-2-Related Hospitalization/Death: Urgent Need for an Update after Diffusion of Anti-COVID Vaccines

  • Francesco Lapi,
  • Ettore Marconi,
  • Alexander Domnich,
  • Iacopo Cricelli,
  • Alessandro Rossi,
  • Ignazio Grattagliano,
  • Giancarlo Icardi and
  • Claudio Cricelli

15 March 2024

Background: There are algorithms to predict the risk of SARS-CoV-2-related complications. Given the spread of anti-COVID vaccination, which sensibly modified the burden of risk of the infection, these tools need to be re-calibrated. Therefore, we upd...

  • Case Report
  • Open Access
1 Citations
3,201 Views
11 Pages

An Aminoglycoside-Sparing Regimen with Double Beta-Lactam to Successfully Treat Granulicatella adiacens Prosthetic Aortic Valve Endocarditis—Time to Change Paradigm?

  • Alberto Pagotto,
  • Floriana Campanile,
  • Paola Conti,
  • Francesca Prataviera,
  • Paola Della Siega,
  • Sarah Flammini,
  • Simone Giuliano,
  • Luca Martini,
  • Davide Pecori and
  • Assunta Sartor
  • + 3 authors

14 March 2024

(1) Background: Granulicatella adiacens is a former nutritionally variant streptococci (NVS). NVS infective endocarditis (IE) is generally characterized by a higher rate of morbidity and mortality, partially due to difficulties in choosing the most a...

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Infect. Dis. Rep. - ISSN 2036-7449