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Case Report

Complications of Percutaneous Endoscopic Gastrostomy-Jejunostomy for Levodopa/Carbidopa Infusion in Advanced Parkinson's Disease

by
Ana Olivares
1,*,
David Collado
1,
Miguel Muñoz-Navas
2,
Marta Calvo
3,
Eduardo Olivo
4,
Inmaculada Chico
1,
Carlos Marra
2,
Rafael Sánchez-Estella
4,
Sarbelio Rodríguez
3,
Josè Carlos Subtil
2 and
Luis Ramon Rábago
1
1
Gastroenterology Department, Hospital Severo Ochoa, Leganés, Madrid, Spain
2
Gastroenterology Department, Clínica Universidad de Navarra, Pamplona, Spain
3
Gastroenterology Department, Hospital Doce de Octubre, Madrid, Spain
4
Surgical Deparment, Hospital Severo Ochoa, Leganés, Madrid, Spain
*
Author to whom correspondence should be addressed.
Gastroenterol. Insights 2012, 4(1), e4; https://doi.org/10.4081/gi.2012.e4
Submission received: 16 August 2011 / Accepted: 22 February 2012 / Published: 6 March 2012

Abstract

Continuous infusions of levodopa directly into the duodenum-yeyunum is an effective therapy to reduce daily off time in an advanced stage of Parkinson's disease, but it is not without complications, particularly device related problems. We present our experience in three Spanish hospitals with these complications, including a severe case with migration, several decubitus ulcers, and one case of perforation of the bowel and finally death.
Keywords: percutaneous endoscopic gastrostomy-tube; levodopa/carbidopa infusion in duodenum; intestinal obstruction; intestinal perforation; endoscopic extraction percutaneous endoscopic gastrostomy-tube; levodopa/carbidopa infusion in duodenum; intestinal obstruction; intestinal perforation; endoscopic extraction

Share and Cite

MDPI and ACS Style

Olivares, A.; Collado, D.; Muñoz-Navas, M.; Calvo, M.; Olivo, E.; Chico, I.; Marra, C.; Sánchez-Estella, R.; Rodríguez, S.; Subtil, J.C.; et al. Complications of Percutaneous Endoscopic Gastrostomy-Jejunostomy for Levodopa/Carbidopa Infusion in Advanced Parkinson's Disease. Gastroenterol. Insights 2012, 4, e4. https://doi.org/10.4081/gi.2012.e4

AMA Style

Olivares A, Collado D, Muñoz-Navas M, Calvo M, Olivo E, Chico I, Marra C, Sánchez-Estella R, Rodríguez S, Subtil JC, et al. Complications of Percutaneous Endoscopic Gastrostomy-Jejunostomy for Levodopa/Carbidopa Infusion in Advanced Parkinson's Disease. Gastroenterology Insights. 2012; 4(1):e4. https://doi.org/10.4081/gi.2012.e4

Chicago/Turabian Style

Olivares, Ana, David Collado, Miguel Muñoz-Navas, Marta Calvo, Eduardo Olivo, Inmaculada Chico, Carlos Marra, Rafael Sánchez-Estella, Sarbelio Rodríguez, Josè Carlos Subtil, and et al. 2012. "Complications of Percutaneous Endoscopic Gastrostomy-Jejunostomy for Levodopa/Carbidopa Infusion in Advanced Parkinson's Disease" Gastroenterology Insights 4, no. 1: e4. https://doi.org/10.4081/gi.2012.e4

APA Style

Olivares, A., Collado, D., Muñoz-Navas, M., Calvo, M., Olivo, E., Chico, I., Marra, C., Sánchez-Estella, R., Rodríguez, S., Subtil, J. C., & Rábago, L. R. (2012). Complications of Percutaneous Endoscopic Gastrostomy-Jejunostomy for Levodopa/Carbidopa Infusion in Advanced Parkinson's Disease. Gastroenterology Insights, 4(1), e4. https://doi.org/10.4081/gi.2012.e4

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