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Neurology International
Volume 4
Issue 2
10.4081/ni.2012.e8
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Neurology International is published by MDPI from Volume 12 Issue 3 (2020). Previous articles were published by another publisher in Open Access under a CC-BY licence, and they are hosted by MDPI on mdpi.com as a courtesy and upon agreement with PAGEPress.
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Case Report

Functional Influence of Botulinum Neurotoxin Type a Treatment (Xeomin®) of Multifocal Upper and Lower Limb Spasticity on Chronic Hemiparetic Gait

by
Maurizio Falso
*,
Rosalba Galluso
and
Andrea Malvicini
Section of Neurological Rehabilitation, Clinical Institute Città di Brescia, Brescia, Italy
*
Author to whom correspondence should be addressed.
Neurol. Int. 2012, 4(2), e8; https://doi.org/10.4081/ni.2012.e8
Submission received: 9 December 2011 / Revised: 26 April 2012 / Accepted: 14 May 2012 / Published: 29 May 2012

Abstract

This report describes the modification of hemiplegic shoulder pain and walking velocity through injections of Xeomin®, a new botulinum neurotoxin type A formulation, in a 67-year-old woman with chronic residual left hemiparesis and hemiparetic gait attributable to stroke. Clinical evaluation included upper and lower limb spasticity, upper and lower limb pain, trunk control, upper and lower limb motricity index, visual gait analysis, and gait velocity. Assessments were performed before, 1 week after, and 1 month after treatment. Improvement was observed in all clinical parameters assessed. Amelioration of spasticity of the upper and lower limbs and shoulder pain was observed after 1 month. Trunk postural attitude and paraxial muscle recruitment recovered. No adverse events were observed and the patient shows significant improvement of functional impairment derived from chronic spasticity after treatment with Xeomin®. We also provide a simple and useful protocol for clinical evaluation of the treatment.
Keywords: botulinum neurotoxin type A; muscle spasticity; Xeomin® botulinum neurotoxin type A; muscle spasticity; Xeomin®

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MDPI and ACS Style

Falso, M.; Galluso, R.; Malvicini, A. Functional Influence of Botulinum Neurotoxin Type a Treatment (Xeomin®) of Multifocal Upper and Lower Limb Spasticity on Chronic Hemiparetic Gait. Neurol. Int. 2012, 4, e8. https://doi.org/10.4081/ni.2012.e8

AMA Style

Falso M, Galluso R, Malvicini A. Functional Influence of Botulinum Neurotoxin Type a Treatment (Xeomin®) of Multifocal Upper and Lower Limb Spasticity on Chronic Hemiparetic Gait. Neurology International. 2012; 4(2):e8. https://doi.org/10.4081/ni.2012.e8

Chicago/Turabian Style

Falso, Maurizio, Rosalba Galluso, and Andrea Malvicini. 2012. "Functional Influence of Botulinum Neurotoxin Type a Treatment (Xeomin®) of Multifocal Upper and Lower Limb Spasticity on Chronic Hemiparetic Gait" Neurology International 4, no. 2: e8. https://doi.org/10.4081/ni.2012.e8

APA Style

Falso, M., Galluso, R., & Malvicini, A. (2012). Functional Influence of Botulinum Neurotoxin Type a Treatment (Xeomin®) of Multifocal Upper and Lower Limb Spasticity on Chronic Hemiparetic Gait. Neurology International, 4(2), e8. https://doi.org/10.4081/ni.2012.e8

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