You are currently viewing a new version of our website. To view the old version click .

Neurology International, Volume 12, Issue 3

December 2020 - 12 articles

Cover Story: Parkinson’s disease (PD) is an increasingly prevalent neurodegenerative condition. The primary pathology is the absence of dopaminergic neurons in the basal ganglion. Many patients with PD experience cycles of deteriorating symptoms called “off episodes”. These episodes are due in part to chronic levodopa therapy, which is one of the disease’s most common treatment methods. This paper provides a comprehensive review of the current literature involving istradefylline, an adenosine A2A-receptor antagonist, for the treatment of off episodes in PD. View this paper
  • Issues are regarded as officially published after their release is announced to the table of contents alert mailing list .
  • You may sign up for email alerts to receive table of contents of newly released issues.
  • PDF is the official format for papers published in both, html and pdf forms. To view the papers in pdf format, click on the "PDF Full-text" link, and use the free Adobe Reader to open them.

Articles (12)

  • Case Report
  • Open Access
1 Citations
3,968 Views
4 Pages

21 December 2020

The jugular foramen and the hypoglossal canal are both apertures located at the base of the skull. Multiple lower cranial nerve palsies tend to occur with injuries to these structures. The pattern of injuries tend to correlate with the combination of...

  • Case Report
  • Open Access
3 Citations
3,438 Views
6 Pages

14 December 2020

Hemichorea–hemiballism (HC–HB) is a spectrum of involuntary flinging and flailing, non-patterned, irregular movements involving one side of the body. A rare dysfunction of glucose metabolism leading to a state of non-ketotic hyperglycemia...

  • Review
  • Open Access
34 Citations
6,287 Views
21 Pages

Istradefylline to Treat Patients with Parkinson’s Disease Experiencing “Off” Episodes: A Comprehensive Review

  • Amnon A. Berger,
  • Ariel Winnick,
  • Alexandra Welschmeyer,
  • Alicia Kaneb,
  • Kevin Berardino,
  • Elyse M. Cornett,
  • Alan D. Kaye,
  • Omar Viswanath and
  • Ivan Urits

8 December 2020

Parkinson’s disease (PD) is a common neurodegenerative disorder that leads to significant morbidity and disability. PD is caused by a loss of dopaminergic, cholinergic, serotonergic, and noradrenergic neurons in the central nervous system (CNS)...

  • Review
  • Open Access
39 Citations
7,040 Views
20 Pages

Ozanimod to Treat Relapsing Forms of Multiple Sclerosis: A Comprehensive Review of Disease, Drug Efficacy and Side Effects

  • Grace Lassiter,
  • Carlie Melancon,
  • Tyler Rooney,
  • Anne-Marie Murat,
  • Jessica S. Kaye,
  • Adam M. Kaye,
  • Rachel J. Kaye,
  • Elyse M. Cornett,
  • Alan D. Kaye and
  • Rutvij J. Shah
  • + 2 authors

3 December 2020

Multiple sclerosis (MS) is a prevalent and debilitating neurologic condition characterized by widespread neurodegeneration and the formation of focal demyelinating plaques in the central nervous system. Current therapeutic options are complex and att...

  • Review
  • Open Access
10 Citations
6,709 Views
12 Pages

24 November 2020

Objective: to find the most up-to-date evidence of the effectiveness and safety of supervised physical therapy in polymyositis/dermatomyositis patients. Methods: a systematic review of the literature in the main scientific databases was carried out....

  • Review
  • Open Access
35 Citations
23,572 Views
16 Pages

Chronic Pain Treatment Strategies in Parkinson’s Disease

  • Amber Edinoff,
  • Niro Sathivadivel,
  • Timothy McBride,
  • Allyson Parker,
  • Chikezie Okeagu,
  • Alan D. Kaye,
  • Adam M. Kaye,
  • Jessica S. Kaye,
  • Rachel J. Kaye and
  • Meeta M. Sheth
  • + 2 authors

18 November 2020

Neurological disorders, including Parkinson’s disease (PD), have increased in prevalence and are expected to further increase in the coming decades. In this regard, PD affects around 3% of the population by age 65 and up to 5% of people over th...

  • Editorial
  • Open Access
2,377 Views
2 Pages

18 November 2020

Having served as editor-in-chief for Neurology International since its inception back in 2009, I am very pleased to see the journal grow and expand, with a major development now taking place with new ownership by MDPI, a world leader in Open Access J...

  • Case Report
  • Open Access
3 Citations
4,025 Views
4 Pages

13 November 2020

Late-onset Pompe disease (LOPD) is an autosomal recessive lysosomal storage disease. Clinical features include skeletal muscle deficiency and diaphragm weakness. Clinical management relies on supportive treatment and mechanical ventilation in patient...

  • Article
  • Open Access
7 Citations
2,838 Views
7 Pages

6 November 2020

Introduction: Gait velocity in spastic patients after stroke is both a life quality and mortality predictor. However, the precise biomechanical events that impair a faster velocity in this population are not defined. This study goal is to find out wh...

  • Case Report
  • Open Access
3 Citations
4,319 Views
7 Pages

30 October 2020

Ependymoblastoma is an uncommon, exceedingly malignant brain neoplasm that adversely influences children’s quality of life. Ependymoblastoma represents a subtype of primitive neuroectodermal tumors, categorized as grade IV, according to the 200...

of 2

Get Alerted

Add your email address to receive forthcoming issues of this journal.

XFacebookLinkedIn
Neurol. Int. - ISSN 2035-8377