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Restrictive Cardiomyopathy and Hypertrophic Cardiomyopathy Overlap: The Importance of the Phenotype

1
Institute of Cardiovascular Science, University College London, UK;
2
Inherited Cardiovascular Diseases Unit, Department of Cardiology, Great Ormond Street Hospital, London, UK
3
Cardiovascular Department, University of Bologna, Italy
4
The Heart Hospital, University College London Hospitals, London, UK
*
Author to whom correspondence should be addressed.
Cardiogenetics 2012, 2(1), e10; https://doi.org/10.4081/cardiogenetics.2012.e10
Submission received: 3 September 2012 / Revised: 6 September 2012 / Accepted: 6 September 2012 / Published: 19 October 2012

Abstract

Restrictive cardiomyopathy (RCM) is defined on the basis of the haemodynamic finding of restrictive ventricular physiology. However, restrictive ventricular pathophysiology is also a feature of other subtypes of cardiomyopathy, including hypertrophic cardiomyopathy (HCM). Clinically and aetiologically, there is an overlap between RCM and HCM with restrictive physiology. However, the clinical distinction between these two entities can be an important pointer towards the underlying aetiology. This review highlights the importance of the recognition of the clinical phenotype as the first step in the classification of cardiomyopathies.
Keywords: cardiomyopathy; sarcomere protein disease; classification; diastology cardiomyopathy; sarcomere protein disease; classification; diastology

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MDPI and ACS Style

Kaski, J.P.; Biagini, E.; Lorenzini, M.; Rapezzi, C.; Elliott, P. Restrictive Cardiomyopathy and Hypertrophic Cardiomyopathy Overlap: The Importance of the Phenotype. Cardiogenetics 2012, 2, e10. https://doi.org/10.4081/cardiogenetics.2012.e10

AMA Style

Kaski JP, Biagini E, Lorenzini M, Rapezzi C, Elliott P. Restrictive Cardiomyopathy and Hypertrophic Cardiomyopathy Overlap: The Importance of the Phenotype. Cardiogenetics. 2012; 2(1):e10. https://doi.org/10.4081/cardiogenetics.2012.e10

Chicago/Turabian Style

Kaski, Juan Pablo, Elena Biagini, Massimo Lorenzini, Claudio Rapezzi, and Perry Elliott. 2012. "Restrictive Cardiomyopathy and Hypertrophic Cardiomyopathy Overlap: The Importance of the Phenotype" Cardiogenetics 2, no. 1: e10. https://doi.org/10.4081/cardiogenetics.2012.e10

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