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Open AccessArticle

Benefits and Prerequisites Associated with the Adoption of Oral 3D-Printed Medicines for Pediatric Patients: A Focus Group Study among Healthcare Professionals

1
HUS Pharmacy, HUS Helsinki University Hospital, Stenbäckinkatu 9 B, 00290 Helsinki, Finland
2
Faculty of Pharmacy, University of Helsinki, Viikinkaari 5 E, 00014 Helsinki, Finland
3
Pharmaceutical Sciences Laboratory, Åbo Akademi University, Tykistökatu 6 A, 20520 Turku, Finland
4
Department of Children and Adolescents, HUS Helsinki University Hospital, Stenbäckinkatu 9, 00290 Helsinki, Finland
*
Author to whom correspondence should be addressed.
Pharmaceutics 2020, 12(3), 229; https://doi.org/10.3390/pharmaceutics12030229
Received: 30 January 2020 / Revised: 28 February 2020 / Accepted: 3 March 2020 / Published: 5 March 2020
(This article belongs to the Special Issue Paediatric Drug Delivery)
The utilization of three-dimensional (3D) printing technologies as innovative manufacturing methods for drug products has recently gained growing interest. From a technological viewpoint, proof-of-concept on the performance of different printing methods already exist, followed by visions about future applications in hospital or community pharmacies. The main objective of this study was to investigate the perceptions of healthcare professionals in a tertiary university hospital about oral 3D-printed medicines for pediatric patients by means of focus group discussions. In general, the healthcare professionals considered many positive aspects and opportunities in 3D printing of pharmaceuticals. A precise dose as well as personalized doses and dosage forms were some of the advantages mentioned by the participants. Especially in cases of polypharmacy, incorporating several drug substances into one product to produce a polypill, personalized regarding both the combination of drug substances and the doses, would benefit drug treatments of several medical conditions and would improve adherence to medications. In addition to the positive aspects, concerns and prerequisites for the adoption of 3D printing technologies at hospital settings were also expressed. These perspectives are suggested by the authors to be focus points for future research on personalized 3D-printed drug products. View Full-Text
Keywords: children; pediatrics; 3D printing; 3D-printed medicines; personalized medication; healthcare professionals; hospital pharmacy; focus group study children; pediatrics; 3D printing; 3D-printed medicines; personalized medication; healthcare professionals; hospital pharmacy; focus group study
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Rautamo, M.; Kvarnström, K.; Sivén, M.; Airaksinen, M.; Lahdenne, P.; Sandler, N. Benefits and Prerequisites Associated with the Adoption of Oral 3D-Printed Medicines for Pediatric Patients: A Focus Group Study among Healthcare Professionals. Pharmaceutics 2020, 12, 229.

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