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Nanomaterial-Based Approaches for Neural Regeneration

1
“Victor Gomoiu” Clinical Children’s Hospital, “Carol Davila” University of Medicine and Pharmacy, 050474 Bucharest, Romania
2
Department of Science and Engineering of Oxide Materials and Nanomaterials, Faculty of Applied Chemistry and Materials Science, Politehnica University of Bucharest, 011061 Bucharest, Romania
3
Lasers Department, National Institute for Lasers, Plasma and Radiation Physics, 077125 Magurele, Romania
4
National Institute of Neurology and Neurovascular Diseases, 077160 Bucharest, Romania
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Emergency University Hospital, “Carol Davila” University of Medicine and Pharmacy, 050474 Bucharest, Romania
*
Author to whom correspondence should be addressed.
Pharmaceutics 2019, 11(6), 266; https://doi.org/10.3390/pharmaceutics11060266
Received: 15 May 2019 / Revised: 3 June 2019 / Accepted: 4 June 2019 / Published: 8 June 2019
(This article belongs to the Special Issue Nanotechnology-Based Approaches for Chronic Diseases)
Mechanical, thermal, chemical, or ischemic injury of the central or peripheral nervous system results in neuron loss, neurite damage, and/or neuronal dysfunction, almost always accompanied by sensorimotor impairment which alters the patient’s life quality. The regenerative strategies for the injured nervous system are currently limited and mainly allow partial functional recovery, so it is necessary to develop new and effective approaches for nervous tissue regenerative therapy. Nanomaterials based on inorganic or organic and composite or hybrid compounds with tunable physicochemical properties and functionality proved beneficial for the transport and delivery/release of various neuroregenerative-relevant biomolecules or cells. Within the following paragraphs, we will emphasize that nanomaterial-based strategies (including nanosized and nanostructured biomaterials) represent a promising alternative towards repairing and regenerating the injured nervous system. View Full-Text
Keywords: nervous system injury; nanomaterial; neuroregeneration nervous system injury; nanomaterial; neuroregeneration
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MDPI and ACS Style

Teleanu, R.I.; Gherasim, O.; Gherasim, T.G.; Grumezescu, V.; Grumezescu, A.M.; Teleanu, D.M. Nanomaterial-Based Approaches for Neural Regeneration. Pharmaceutics 2019, 11, 266.

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