Chordoma Spontaneous Regression After COVID-19
Abstract
:1. Introduction
2. Case Report
3. Discussion
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Acknowledgments
Conflicts of Interest
References
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Radl et al., 2005 [4] | Bander et al., 2020 [5] | Passeri et al., 2020 [6] | Vellutini et al., 2021 [7] | This Case | |
---|---|---|---|---|---|
Location | Spine (C2) | Clivus | Clivus | Clivus | Clivus, C1–C2 |
Gender | Male | Female | Male | Female | Female |
Symptoms | Neck pain, paresthesia, urinary and bowel disfunction, hyperreflexia | Stabbing headache | No. | Headache | Headache, neck pain, right hemiplegia, tongue palsy |
Measure pre-regression | 2.5 × 2 × 4 cm | 3.1 × 1.9 × 3 cm (8.84 cm3) | 36.9 cm3 | - | 6.5 × 3.5 × 4.5 cm (102.37 cm3) |
Measure post-regression | - | 2.3 × 2.1 × 1.4 cm (3.38 cm3) | 24.7 cm3 | - | 1.6 × 0.7 × 1 cm (1.12 cm3) |
Medications used | Dexamethasone, ciprofloxacin | Gabapentin, famotidine, loratadine, hydralazine, atenolol, nitroglycerin patch, vitamin B2, B6, B12. Complex of resveratrol, E-alpha-lipoic acid, hyaluronic acid, astaxanthin, echinacea, badger fat/oil tablets, sea buckhorn oil. | Corticosteroids, clarithromycin, doxycicline | - | Dexamethasone, meropenem, amikacin, ceftriaxone, clindamycin, azithromycin, hydroxycloroquine, ivermectin, prednisone, zinc and vitamin d, gabapentin, amitriptyline |
Associated infection | Yes. Local abcess | No. | Yes. Inflammatory bullous dermatosis | No | COVID-19 |
Agent | Escherichia coli | - | Mycobacterium marinum | - | SARS-CoV-2 |
Pre-regression surgery | 2. Biopsies | No | No | No | Fixation C0-C1-C2 |
Post-regression treatment | No. Complete regression | Ressection | Wait-and-see | Ressection | Ressection |
PO fever | Yes | No | - | - | Yes |
Histopathology | Chordoma | Chordoma | - | Chordoma | Chordoma |
Brachyury | - | Negative | - | Positive | Positive |
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Silva Junior, L.F.M.d.; Silva, G.E.B.; Campos, M.A.G.; Teixeira Júnior, A.A.L.; Santos, R.M.; Santos, O.J.d.; Salgado Filho, N. Chordoma Spontaneous Regression After COVID-19. Viruses 2025, 17, 10. https://doi.org/10.3390/v17010010
Silva Junior LFMd, Silva GEB, Campos MAG, Teixeira Júnior AAL, Santos RM, Santos OJd, Salgado Filho N. Chordoma Spontaneous Regression After COVID-19. Viruses. 2025; 17(1):10. https://doi.org/10.3390/v17010010
Chicago/Turabian StyleSilva Junior, Luis Fernando Moura da, Gyl Eanes Barros Silva, Marcos Adriano Garcia Campos, Antonio Augusto Lima Teixeira Júnior, Ramon Moura Santos, Orlando José dos Santos, and Natalino Salgado Filho. 2025. "Chordoma Spontaneous Regression After COVID-19" Viruses 17, no. 1: 10. https://doi.org/10.3390/v17010010
APA StyleSilva Junior, L. F. M. d., Silva, G. E. B., Campos, M. A. G., Teixeira Júnior, A. A. L., Santos, R. M., Santos, O. J. d., & Salgado Filho, N. (2025). Chordoma Spontaneous Regression After COVID-19. Viruses, 17(1), 10. https://doi.org/10.3390/v17010010