Next Article in Journal
Uncertainty Evaluation of Weibull Estimators through Monte Carlo Simulation: Applications for Crack Initiation Testing
Next Article in Special Issue
Tunability of Size and Magnetic Moment of Iron Oxide Nanoparticles Synthesized by Forced Hydrolysis
Previous Article in Journal
Influence of Pre-Sintered Zirconia Surface Conditioning on Shear Bond Strength to Resin Cement
Previous Article in Special Issue
Calcium Phosphate as a Key Material for Socially Responsible Tissue Engineering
Article Menu
Issue 7 (July) cover image

Export Article

Open AccessFeature PaperReview
Materials 2016, 9(7), 520;

Curcumin and Osteosarcoma: Can Invertible Polymeric Micelles Help?

Department of Orthopedics, Mayo Clinic, 200 1st St SW, Rochester, MN 55905, USA
Department of Organic Chemistry, Lviv Polytechnic National University, vul. S. Bandery, 12, Lviv 79013, Ukraine
Department of Coatings and Polymeric Materials, North Dakota State University, NDSU Dept. 2760, P.O. Box 6050, Fargo, ND 58108-6050, USA
Author to whom correspondence should be addressed.
Academic Editor: Carlos Lodeiro
Received: 17 May 2016 / Revised: 21 June 2016 / Accepted: 23 June 2016 / Published: 27 June 2016
(This article belongs to the Special Issue Selected papers from ISN2A2016)
Full-Text   |   PDF [1813 KB, uploaded 27 June 2016]   |  


Systematic review of experimental and clinical data on the use of curcumin in the treatment of osteosarcoma is presented. The current status of curcumin’s therapeutic potential against bone cancer is analyzed in regard to using polymeric micelles (including recently developed invertible, responsive, micelles) as a platform for curcumin delivery to treat osteosarcoma. The potential of micellar assemblies from responsive macromolecules in a controlled delivery of curcumin to osteosarcoma cells, and the release using a new inversion mechanism is revealed. View Full-Text
Keywords: invertible polymer micelles; micellar nanoassemblies; curcumin delivery; bone tumor treatment invertible polymer micelles; micellar nanoassemblies; curcumin delivery; bone tumor treatment

Figure 1

This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited (CC BY 4.0).

Share & Cite This Article

MDPI and ACS Style

Maran, A.; Yaszemski, M.J.; Kohut, A.; Voronov, A. Curcumin and Osteosarcoma: Can Invertible Polymeric Micelles Help? Materials 2016, 9, 520.

Show more citation formats Show less citations formats

Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Related Articles

Article Metrics

Article Access Statistics



[Return to top]
Materials EISSN 1996-1944 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert
Back to Top