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The Correlation of Pore Size and Bioactivity of Spray-Pyrolyzed Mesoporous Bioactive Glasses

Department of Materials, University of Oxford, Oxford OX1 3PH, UK
Department of Materials Science and Engineering, National Taiwan University of Science and Technology, Taipei 10607, Taiwan
Horien Biochemical Technology Co., Ltd., Taichung 40768, Taiwan
School of Dentistry, National Taiwan University, Taipei 10048, Taiwan
Department of Dentistry, National Taiwan University Hospital, Taipei 10048, Taiwan
Authors to whom correspondence should be addressed.
Academic Editor: James Z. Tang
Materials 2017, 10(5), 488;
Received: 7 March 2017 / Revised: 28 April 2017 / Accepted: 28 April 2017 / Published: 3 May 2017
(This article belongs to the Special Issue Materials for Drug Delivery and Biomedical Consideration)
PDF [3340 KB, uploaded 3 May 2017]


SiO2–CaO–P2O5-based mesoporous bioactive glasses (MBGs) were synthesized by spray pyrolysis in this study. Three commonly used non-ionic tri-block copolymers (L121, P123, and F127) with various lengths of hydrophilic chains were applied as structural templates to achieve different pore sizes. A mesoporous structure was observed in each as-prepared specimen, and the results showed that the L121-treated MBG had the largest pore size. The results of bioactivity tests indicated that the growth of hydroxyapatite is related to the pore size of the materials. View Full-Text
Keywords: mesoporous bioactive glasses; surfactants; pore size; bioactivity mesoporous bioactive glasses; surfactants; pore size; bioactivity

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Chou, Y.-J.; Hong, B.-J.; Lin, Y.-C.; Wang, C.-Y.; Shih, S.-J. The Correlation of Pore Size and Bioactivity of Spray-Pyrolyzed Mesoporous Bioactive Glasses. Materials 2017, 10, 488.

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