Next Article in Journal
Combining Prostate Cancer Radiotherapy with Therapies Targeting the Androgen Receptor Axis
Previous Article in Journal
OCTANE (Ontario-Wide Cancer Targeted Nucleic Acid Evaluation): A Platform for Intraprovincial, National, and International Clinical Data-Sharing
 
 
Search for Articles:
Title / Keyword
Author / Affiliation / Email
Journal
Article Type
 
 
Advanced Search
 
Section
Special Issue
Volume
Issue
Number
Page
 
Journals
Current Oncology
Volume 26
Issue 5
10.3747/co.26.5003
curroncol-logo
Submit to this Journal Review for this Journal Propose a Special Issue
► Article Menu

Article Menu

share Share announcement Help format_quote Cite question_answer Discuss in SciProfiles thumb_up
...
Endorse textsms
...
Comment
Current Oncology is published by MDPI from Volume 28 Issue 1 (2021). Previous articles were published by another publisher in Open Access under a CC-BY (or CC-BY-NC-ND) licence, and they are hosted by MDPI on mdpi.com as a courtesy and upon agreement with Multimed Inc..
first_page
settings
Order Article Reprints
Font Type:
Arial Georgia Verdana
Font Size:
Aa Aa Aa
Line Spacing:
Column Width:
Background:
Article

Cross-Canada Differences in Early-Stage Breast Cancer Treatment and Acute-Care Use

by
M. Powis
1,
P. Groome
2,
N. Biswanger
3,
C. Kendell
4,
K.M. Decker
5,6,
E. Grunfeld
7,
M.L. McBride
8,
R. Urquhart
9,
M. Winget
10,
G.A. Porter
11 and
M.K. Krzyzanowska
1,*
1
Division of Medical Oncology and Hematology, Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada
2
Division of Cancer Care and Epidemiology, Cancer Research Institute, Queen’s University, Kingston, ON, Canada
3
Epidemiology and Cancer Registry Department, CancerCare Manitoba, Winnipeg, MB, Canada
4
Cancer Outcomes Research Program, Department of Surgery, Dalhousie University and Nova Scotia Health Authority, Halifax, NS, Canada
5
Department of Community Health Sciences, University of Manitoba, Winnipeg, MB, Canada
6
Epidemiology and Cancer Registry, CancerCare Manitoba, Winnipeg, MB, Canada
7
Department of Family and Community Medicine, University of Toronto, Toronto, ON, Canada
8
Cancer Control Research, BC Cancer, Vancouver, BC, Canada
9
Dalhousie University, Halifax, NS, Canada
10
Stanford University School of Medicine, Stanford, CA, USA
11
Department of Surgery, Queen Elizabeth ii Health Sciences Centre, Halifax, NS, Canada
 
add Show full affiliation list
 
remove Hide full affiliation list
*
Author to whom correspondence should be addressed.
Curr. Oncol. 2019, 26(5), 624-639; https://doi.org/10.3747/co.26.5003
Submission received: 9 July 2019 / Revised: 14 August 2019 / Accepted: 9 September 2019 / Published: 1 October 2019

Abstract

Background: Chemotherapy has improved outcomes in early-stage breast cancer, but treatment practices vary, and use of acute care is common. We conducted a pan-Canadian study to describe treatment differences and the incidence of emergency department visits (EDVS), edvs leading to hospitalization (EDVHS), and direct hospitalizations (HS) during adjuvant chemotherapy. Methods: The cohort consisted of women diagnosed with early-stage breast cancer (stages I–III) during 2007–2012 in British Columbia, Manitoba, Ontario, or Nova Scotia who underwent curative surgery. Parallel provincial analyses were undertaken using linked clinical, registry, and administrative databases. The incidences of edvs, edvhs, and hs in the 6 months after treatment initiation were examined for patients treated with adjuvant chemotherapy. Results: The cohort consisted of 50,224 patients. The proportion of patients who received chemotherapy varied by province, with Ontario having the highest proportion (46.4%), and Nova Scotia, the lowest proportion (38.0%). Age, stage, receptor status, comorbidities, and geographic location were associated with receipt of chemotherapy in all provinces. Ontario had the highest proportion of patients experiencing an EDV (36.1%), but the lowest proportion experiencing H (6.4%). Conversely, British Columbia had the lowest proportion of patients experiencing an EDV (16.0%), but the highest proportion experiencing H (26.7%). The proportion of patients having an edvh was similar across provinces (13.9%–16.8%). Geographic location was associated with EDVS, EDVHS, and HS in all provinces. Conclusions: Intra- and inter-provincial differences in the use of chemotherapy and acute care were observed. Understanding variations in care can help to identify gaps and opportunities for improvement and shared learnings.
Keywords: breast cancer; systemic therapy; administrative data; hospitalizations; emergency department visits breast cancer; systemic therapy; administrative data; hospitalizations; emergency department visits

Share and Cite

MDPI and ACS Style

Powis, M.; Groome, P.; Biswanger, N.; Kendell, C.; Decker, K.M.; Grunfeld, E.; McBride, M.L.; Urquhart, R.; Winget, M.; Porter, G.A.; et al. Cross-Canada Differences in Early-Stage Breast Cancer Treatment and Acute-Care Use. Curr. Oncol. 2019, 26, 624-639. https://doi.org/10.3747/co.26.5003

AMA Style

Powis M, Groome P, Biswanger N, Kendell C, Decker KM, Grunfeld E, McBride ML, Urquhart R, Winget M, Porter GA, et al. Cross-Canada Differences in Early-Stage Breast Cancer Treatment and Acute-Care Use. Current Oncology. 2019; 26(5):624-639. https://doi.org/10.3747/co.26.5003

Chicago/Turabian Style

Powis, M., P. Groome, N. Biswanger, C. Kendell, K.M. Decker, E. Grunfeld, M.L. McBride, R. Urquhart, M. Winget, G.A. Porter, and et al. 2019. "Cross-Canada Differences in Early-Stage Breast Cancer Treatment and Acute-Care Use" Current Oncology 26, no. 5: 624-639. https://doi.org/10.3747/co.26.5003

APA Style

Powis, M., Groome, P., Biswanger, N., Kendell, C., Decker, K. M., Grunfeld, E., McBride, M. L., Urquhart, R., Winget, M., Porter, G. A., & Krzyzanowska, M. K. (2019). Cross-Canada Differences in Early-Stage Breast Cancer Treatment and Acute-Care Use. Current Oncology, 26(5), 624-639. https://doi.org/10.3747/co.26.5003

Article Metrics

Back to TopTop