Next Article in Journal
Genitourinary Small-Cell Carcinoma: A Single-Institution Experience
Previous Article in Journal
Bevacizumab-Based Therapy for Colorectal Cancer: Experience from a Large Canadian Cohort at the Jewish General Hospital between 2004 and 2009
 
 
Search for Articles:
Title / Keyword
Author / Affiliation / Email
Journal
Article Type
 
 
Advanced Search
 
Section
Special Issue
Volume
Issue
Number
Page
 
Journals
Current Oncology
Volume 20
Issue 5
10.3747/co.20.1646
curroncol-logo
Submit to this Journal Review for this Journal Propose a Special Issue
► Article Menu

Article Menu

share Share announcement Help format_quote Cite question_answer Discuss in SciProfiles thumb_up
...
Endorse textsms
...
Comment
Current Oncology is published by MDPI from Volume 28 Issue 1 (2021). Previous articles were published by another publisher in Open Access under a CC-BY (or CC-BY-NC-ND) licence, and they are hosted by MDPI on mdpi.com as a courtesy and upon agreement with Multimed Inc..
first_page
settings
Order Article Reprints
Font Type:
Arial Georgia Verdana
Font Size:
Aa Aa Aa
Line Spacing:
Column Width:
Background:
Article

Colorectal Cancer Screening in Canada: Results from the First Round of Screening for Five Provincial Programs

by
D. Major
1,*,
H. Bryant
2,
M. Delaney
3,
S. Fekete
1,
L. Gentile
4,
M. Harrison
5,
V. Mai
1,
E. Nicholson
6 and
Y. Taylor
7 on behalf of the Colorectal Cancer Screening Monitoring Program Performance Working Group and the Canadian Partnership Against Cancer
1
Screening and Early Detection Portfolio, Canadian Partnership Against Cancer, Toronto, ON, Canada
2
Cancer Control Division, Canadian Partnership Against Cancer, Toronto, ON, Canada
3
Chronic Disease Prevention and Management Unit, Health PEI, Charlottetown, PE, Canada
4
Cancer Screening, BC Cancer Agency, Vancouver, BC, Canada
5
Screening Programs, Cancer Care Manitoba, Winnipeg, MB, Canada
6
Cancer Prevention and Early Detection, Cancer Care Nova Scotia, Halifax, NS, Canada
7
Early Detection, Population Health, Saskatchewan Cancer Agency, Regina, SK, Canada
*
Author to whom correspondence should be addressed.
Curr. Oncol. 2013, 20(5), 252-257; https://doi.org/10.3747/co.20.1646
Submission received: 11 July 2013 / Revised: 10 August 2013 / Accepted: 8 September 2013 / Published: 1 October 2013

Abstract

Background: Early implementation of programmatic colorectal cancer (CRC) screening for average-risk individuals 50–74 years of age in Canada has used fecal occult blood tests [FTS (guaiac or immunochemical)] and colonoscopy for follow-up of abnormal FTS. This paper presents results of an evaluation of this CRC screening. Methods: Five Canadian provincial programs provided aggregated data for individuals with a first-round FT processed between January 1, 2009, and December 31, 2011. Results: The 104,750 people who successfully completed a first round of screening represented 16.1% of those who had access to the programs between January 1, 2009, and December 31, 2011 (mean age: 61.2 years; men: 61.4 years; women: 61.1 years). Of those participants, 4661 had an abnormal FT (4.4%). Uptake of colonoscopy within 180 days after an abnormal FT was 80.5%, ranging from 67.8% to 89.5% by program. The positive predictive value (PPV) for adenoma was 35.9% for guaiac FT and 50.6% for immunochemical FT. Adenoma and CRC detection rates were, respectively, 16.9 and 1.8 per 1000 screened. Of invasive crcs detected, 64.6% were stage I or II. Conclusions: Considering the variation in characteristics and stage of implementation of each provincial program, the collaboration of the provinces leading to this report on the early performance of CRC screening in Canada is a major milestone. Targets are met or nearly met for significant indicators such as PPV for adenoma and cancer detection rate. Participation is expected to increase as programs are fully implemented in the provinces. Additional effort may be needed to improve timely access to follow-up colonoscopy.
Keywords: colorectal cancer; screening programs; fecal occult blood test; guaiac; immunochemical; average risk colorectal cancer; screening programs; fecal occult blood test; guaiac; immunochemical; average risk

Share and Cite

MDPI and ACS Style

Major, D.; Bryant, H.; Delaney, M.; Fekete, S.; Gentile, L.; Harrison, M.; Mai, V.; Nicholson, E.; Taylor, Y., on behalf of the Colorectal Cancer Screening Monitoring Program Performance Working Group and the Canadian Partnership Against Cancer. Colorectal Cancer Screening in Canada: Results from the First Round of Screening for Five Provincial Programs. Curr. Oncol. 2013, 20, 252-257. https://doi.org/10.3747/co.20.1646

AMA Style

Major D, Bryant H, Delaney M, Fekete S, Gentile L, Harrison M, Mai V, Nicholson E, Taylor Y on behalf of the Colorectal Cancer Screening Monitoring Program Performance Working Group and the Canadian Partnership Against Cancer. Colorectal Cancer Screening in Canada: Results from the First Round of Screening for Five Provincial Programs. Current Oncology. 2013; 20(5):252-257. https://doi.org/10.3747/co.20.1646

Chicago/Turabian Style

Major, D., H. Bryant, M. Delaney, S. Fekete, L. Gentile, M. Harrison, V. Mai, E. Nicholson, and Y. Taylor on behalf of the Colorectal Cancer Screening Monitoring Program Performance Working Group and the Canadian Partnership Against Cancer. 2013. "Colorectal Cancer Screening in Canada: Results from the First Round of Screening for Five Provincial Programs" Current Oncology 20, no. 5: 252-257. https://doi.org/10.3747/co.20.1646

APA Style

Major, D., Bryant, H., Delaney, M., Fekete, S., Gentile, L., Harrison, M., Mai, V., Nicholson, E., & Taylor, Y., on behalf of the Colorectal Cancer Screening Monitoring Program Performance Working Group and the Canadian Partnership Against Cancer. (2013). Colorectal Cancer Screening in Canada: Results from the First Round of Screening for Five Provincial Programs. Current Oncology, 20(5), 252-257. https://doi.org/10.3747/co.20.1646

Article Metrics

Back to TopTop