Cardiovascular Medicine

3 pages, 1892 KB

Open AccessInteresting Images

Wide-Complex Tachycardia with Heart Failure

by Sven Reek, Hans O. Gloor and Hansjörg Meier

Cardiovasc. Med. 2012, 15(10), 298; https://doi.org/10.4414/cvm.2012.00106 - 24 Oct 2012

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A 67-year-old male patient presented with dyspnoea and chest discomfort during mild physical activity. The medical history was unremarkable, apart from a tick bite five years ago [...] Full article

2 pages, 1838 KB

Open AccessInteresting Images

A Tachycardia with QRS Duration Narrower Than That During Sinus Rhythm

by Danielle Zaugg Longchamp and Etienne Pruvot

Cardiovasc. Med. 2012, 15(10), 296; https://doi.org/10.4414/cvm.2012.00107 - 24 Oct 2012

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Abstract

An 83-year-old man with ischaemic heart disease and a triple bypass in 2007 presented to the emergency department with increasing shortness of breath and weight gain of 5 kg over one month [...] Full article

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Valentine in the Heart

by Panneerselvam Arunkumar and Ramasamy Palanimuthu

Cardiovasc. Med. 2012, 15(10), 295; https://doi.org/10.4414/cvm.2012.00108 - 24 Oct 2012

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Abstract

A 45-year-old male with recent anterior wall infarction underwent coronary angiogram. [...] Full article

2 pages, 1843 KB

Open AccessCase Report

Ruptured Neoatherosclerosis as Source of Late Stent Thrombosis

by Mathieu Stadelmann, Jérémy Valentin, Marie-Noelle Giraud and Stéphane Cook

Cardiovasc. Med. 2012, 15(10), 293; https://doi.org/10.4414/cvm.2012.00105 - 24 Oct 2012

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Abstract

Neoatherosclerosis has been termed to define neointimal atherosclerotic changes occurring within a coronary stent [1,2]. Based on histological [2] and angioscopic studies [3], rupture within the neointima has been reported in the long-term after coronary stent implantation and has been proposed to be [...] Read more.

Neoatherosclerosis has been termed to define neointimal atherosclerotic changes occurring within a coronary stent [1,2]. Based on histological [2] and angioscopic studies [3], rupture within the neointima has been reported in the long-term after coronary stent implantation and has been proposed to be responsible for late and very late stent thrombosis. More recently, optical coherence tomography (OCT) with high discriminating power has been proposed to characterise this phenomenon in daily practice [4,5]. Full article

6 pages, 1788 KB

Open AccessEditorial

Cerebral Protection Devices for Transcatheter Aortic Valve Implantation

by Fabian Nietlispach

Cardiovasc. Med. 2012, 15(10), 287; https://doi.org/10.4414/cvm.2012.00104 - 24 Oct 2012

Cited by 3 | Viewed by 15

Abstract

Ever since the publication of the PARTNER trials, the spotlight has turned to neurologic events during transcatheter aortic valve i mplantation ( TAVI). Recently published long-term follow-up data mitigated the initial concerns, however, stroke prevention during TAVI remains an important issue. This review [...] Read more.

Ever since the publication of the PARTNER trials, the spotlight has turned to neurologic events during transcatheter aortic valve i mplantation ( TAVI). Recently published long-term follow-up data mitigated the initial concerns, however, stroke prevention during TAVI remains an important issue. This review article focuses on the currently available cerebral protection devices for TAVI and puts them in perspective of the overall “stroke issue”. Cerebral protection devices either deflect emboli (Embrella, EDD) or capture them (Claret, EmbolX). In TAVI, only first-in-human studies with those devices are currently published, with all of them showing technical feasibility. Larger trials are underway and will shed light on the role of cerebral protection devices during TAVI and their clinical impact on preventing neurologic events. Full article

11 pages, 2254 KB

Open AccessEditorial

MitraClip for the Treatment of Mitral Regurgitation

by Oliver Gaemperli and Roberto Corti

Cardiovasc. Med. 2012, 15(10), 276; https://doi.org/10.4414/cvm.2012.00103 - 24 Oct 2012

Cited by 4 | Viewed by 9

Abstract

Percutaneous mitral valve repair (MVR) using the MitraClip system is a novel and promising technique for the treatment of mitral regurgitation (MR) which involves mechanical edge-to-edge coaptation of the mitral leaflets and has been employed in over 5,000 patients worldwide. Its feasibility and [...] Read more.

Percutaneous mitral valve repair (MVR) using the MitraClip system is a novel and promising technique for the treatment of mitral regurgitation (MR) which involves mechanical edge-to-edge coaptation of the mitral leaflets and has been employed in over 5,000 patients worldwide. Its feasibility and high procedural success rates have been established in several small single- or multi-centric registries and one randomised controlled trial, and cardiovascular outcomes in highrisk surgical patients appear to be superior to historical controls. Overall, the procedure has proven to be safe with exceedingly low rates of fatal or life-threatening complications. Additionally, significant improvements in functional capacity and quality of life have been reported following MitraClip implantation. However, apart from these encouraging results, open questions remain to be addressed, particularly about longterm durability and clinical efficacy, and the selection of the most appropriate candidates for MitraClip implantation. As the experience with this procedure continues to expand, larger studies are expected that will help to further define the role of the MitraClip procedure among established therapies. Full article

5 pages, 1634 KB

Open AccessReview

Curing by Burning? What to Expect from Renal Denervation in the Treatment of Arterial Hypertension

by Antoinette Pechère-Bertschia, Georg Ehret, Marco Roffi, Robert Francis Bonvini, François Mach and Pierre-Yves Martin

Cardiovasc. Med. 2012, 15(10), 271; https://doi.org/10.4414/cvm.2012.00102 - 24 Oct 2012

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Abstract

Renal denervation is a new promising intervention for refractory hypertension. It uses ablation of the renal sympathetic nerves with a radio-frequency-emitting catheter inserted percutaneously via the femoral artery into the lumen of both renal arteries. Reducing sympathetic activity with total sympathectomy in order [...] Read more.

Renal denervation is a new promising intervention for refractory hypertension. It uses ablation of the renal sympathetic nerves with a radio-frequency-emitting catheter inserted percutaneously via the femoral artery into the lumen of both renal arteries. Reducing sympathetic activity with total sympathectomy in order to treat high blood pressure has been utilised in the 1940s but was abandoned for high complication rates. This new, more focalised approach allows for an impressive blood pressure reduction in office blood pressure. New data also show that this method may reduce sleep apnoea syndrome, some parameters of the metabolic syndrome, and heart rate and PR intervals as indicators of reduced sympathetic activity. Altogether, this approach appears to be a safe and effective therapeutic approach to lower blood pressure, but only in highly selected patients with resistant hypertension, and after state-of-the-art optimised treatment in expert centres. A close follow-up of these patients after the procedure is also required. The indications of renal denervation, some technical aspects, perspectives and limitations are developed in this review. Full article

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Cardiovasc. Med., Volume 15, Issue 10 (10 2012) – 7 articles

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