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Nutraceuticals, Volume 6, Issue 2

2026 June - 21 articles

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Articles (21)

  • Feature Paper
  • Article
  • Open Access
1,379 Views
14 Pages

Dietary Supplementation with Litsea cubeba Leaves Alleviates Dextran Sulfate Sodium-Induced Ulcerative Colitis in Mice by Preserving Key Functional Components of the Colonic Barrier

  • Bungo Shirouchi,
  • Mai Okumura,
  • Shiori Iwasaki,
  • Shigeki Oogai and ,
  • Kaede Yamasaki,
  • Hiroyuki Katsuragi,
  • Yasuo Nagata,
  • Keisuke Tsuge,
  • Kazunori Koba and
  • Teruyoshi Yanagita
  • + 5 authors+ 0 author

The leaves and bark of Litsea species have traditionally been used as folk medicine to treat pain, headache, inflammation, diarrhea, and gastroenteritis. This study investigated whether dietary supplementation with Litsea cubeba leaves could preserve...

(This article belongs to the Topic Functional Foods and Nutraceuticals in Health and Disease)
  • Article
  • Open Access
1,031 Views
31 Pages

Optimization of Microencapsulated Eggplant Biomass Extracts: Bioaccessibility, Permeability, and Antiproliferative Activity

  • Emilia Saraí Rodríguez-Miranda,
  • Marilena Antunes-Ricardo,
  • José Basilio Heredia,
  • Nayely Leyva-López and ,
  • Erick Paul Gutiérrez-Grijalva,
  • Pedro de Jesús Bastidas-Bastidas and
  • Laura Aracely Contreras-Angulo
  • + 2 authors+ 0 author

Eggplant is a crop of significant global importance. However, strict selection criteria generate large amounts of biomass that contain hydrophilic bioactive compounds. These compounds are associated with the prevention and treatment of diseases such...

  • Editorial
  • Open Access
2 Citations
1,119 Views
4 Pages

Nutraceuticals and Their Anti-Inflammatory Effects

  • José Carlos Tavares Carvalho and
  • Caio Pinho Fernandes

Inflammation is an essential biological response that enables host defense, tissue repair, and restoration of homeostasis after injury or infection [...]

(This article belongs to the Special Issue Nutraceuticals and Their Anti-inflammatory Effects)
  • Review
  • Open Access
1 Citations
2,439 Views
24 Pages

Nutraceutical Strategies for Blood Pressure Control: Mechanisms, Evidence, and Clinical Implications

  • Tea Vrcelj,
  • Vlatka Buzjak Služek,
  • Marina Ferenac Kiš,
  • Viduranga Y. Waisundara and
  • Ines Banjari

Hypertension frequently remains uncontrolled despite pharmacological therapy, supporting interest in complementary nutritional strategies. This narrative review evaluates human clinical evidence and mechanistic pathways for minerals, polyphenols, ome...

(This article belongs to the Special Issue Feature Review Papers in Nutraceuticals)
  • Article
  • Open Access
2,731 Views
16 Pages

Short-Term Methylcobalamin Supplementation Is Associated with Changes in Anaerobic and Cognitive Performance in Amateur Cyclists: A Randomized Crossover Trial

  • Francisco Javier Martínez-Noguera,
  • Pedro E. Alcaraz,
  • Francisco Jesús González Blanc,
  • Thomas G. Huyghe and
  • Cristian Marín-Pagán

Introduction: Vitamin B12 (VB12), particularly its active form methylcobalamin (MeB12), contributes to neuromuscular function and energy metabolism, which may be relevant for sports performance. However, evidence on the acute effects of MeB12 supplem...

  • Article
  • Open Access
1 Citations
1,288 Views
18 Pages

Phytochemical Evaluation of Wild-Grown Rosehips from Native Greek Rosa canina Genotypes

  • Theodora Papagrigoriou,
  • Efstathia Patelou,
  • Charikleia Paloukopoulou,
  • Stefanos Kostas and ,
  • Angelos K. Kanellis and
  • Diamanto Lazari
  • + 1 author+ 0 author

Rosehip (the “fruit” of Rosa canina L, commonly known as dog rose) is an emerging functional food, yet native Greek populations remain under-explored. This study screened 76 wild genotypes from Northern Greece for radical scavenging activ...

  • Article
  • Open Access
1,013 Views
22 Pages

Subfractionation of Pistacia lentiscus L. var. Chia Neutral Fractions: Chemical Analysis and Evaluation of Their Biological Profiling

  • Foteini D. Kalousi,
  • Achilleas Georgantopoulos,
  • Aurora Camola,
  • Natasa P. Kalogiouri and ,
  • Federica Pollastro and
  • Anna-Maria G. Psarra
  • + 1 author+ 0 author

Pistacia lentiscus L. var. Chia is an endemic tree cultivated in the Southern part of Chios Greek Island. Chios mastiha, the aromatic resin secreted from this tree, has been used as traditional remedy since ancient times to cure many peptic system di...

(This article belongs to the Topic Functional Foods and Nutraceuticals in Health and Disease)
  • Review
  • Open Access
1 Citations
1,708 Views
17 Pages

Recent Advances in the Use of Hop Extracts in Medicine, Food Science and Agriculture

  • James Billam,
  • Omoniteni Akinlotan,
  • Michail Karavolos,
  • Sami Faour and
  • Georgios Efthimiou

Hops (Humulus lupulus L.) is a plant species with a multitude of uses in medicine, food science and agriculture. Xanthohumol, the major prenylflavonoid in hop cone extract, possesses anti-cancer activity. Xanthohumol also exhibits strong antimicrobia...

  • Review
  • Open Access
13,587 Views
15 Pages

Ecdysterone: A Component of Dietary Supplements with Ergogenic Potential?

  • Sareli Alonso León,
  • Berta Pinto Robayna,
  • Carlos Díaz Romero and
  • Néstor Benítez Brito

Ecdysterone is a natural compound proposed as an alternative to anabolic-androgenic steroids (AAS) due to its comparable ergogenic potential and more favorable safety profile. This narrative review summarizes current evidence using a standardized sea...

(This article belongs to the Special Issue Feature Review Papers in Nutraceuticals)
  • Article
  • Open Access
2,381 Views
19 Pages

Four Weeks of CreaSol®Tyrosol Plus Creatine Supplementation Enhances Training Volume and Strength Endurance: A Randomized, Double-Blind, Placebo-Controlled Trial

  • Eric M. Sikorski,
  • Tony M. Zavala,
  • Kenneth B. Hawkins,
  • Gabriel J. Wilson and ,
  • Charlie Ottinger,
  • Ryan Lowery and
  • Jacob M. Wilson
  • + 2 authors+ 0 author

Tyrosol, a phenolic compound derived from olive products, exhibits anti-inflammatory, neuroprotective, and cardiometabolic properties, whereas creatine is a well-established ergogenic aid with documented benefits for muscular performance and emerging...

  • Review
  • Open Access
2 Citations
2,692 Views
18 Pages

Polyphenols and Cardiovascular Diseases: Molecular Insights and Nutraceutical Advances

  • Ana Cecilia Cepeda-Nieto,
  • Ileana Vera-Reyes,
  • Gilberto Esquivel-Muñoz,
  • Carlos Barrera-Ramírez and ,
  • Raúl Rodríguez-Herrera,
  • Jesús A. Padilla-Gámez,
  • Eduardo Meneses-Sierra,
  • Sunday Sedodo Nupo and
  • Jesús Antonio Morlett-Chávez
  • + 4 authors+ 0 author

Cardiovascular diseases (CVDs) remain the leading cause of morbidity and mortality worldwide. Despite their often-asymptomatic progression and complex therapeutic management, a substantial proportion of CVDs is preventable through early intervention...

(This article belongs to the Topic Functional Foods and Nutraceuticals in Health and Disease)
  • Article
  • Open Access
1 Citations
1,639 Views
20 Pages

Oilseed consumption in Morocco has seen enhanced relevance due to its nutrient and functional value. This research paper was undertaken to establish the most consumed oilseeds in the country and to compare their chemical profiles, nutritional content...

  • Correction
  • Open Access
579 Views
2 Pages

Correction: Di Simone et al. Unravelling the Neuroprotective Effects of a Novel Formulation Based on Plant Extracts, Mg, and Vitamin B6. Nutraceuticals 2025, 5, 5

  • Simonetta Cristina Di Simone,
  • Alessandra Acquaviva,
  • Maria Loreta Libero,
  • Nilofar Nilofar and ,
  • Fatma Tunali,
  • Paola Angelini,
  • Giancarlo Angeles Flores,
  • Gaia Cusumano,
  • Lucia Recinella and
  • Annalisa Chiavaroli
  • + 10 authors+ 5 authors

References Update [...]

  • Review
  • Open Access
5 Citations
2,408 Views
43 Pages

Silymarin as a Redox-Signalling and Proteostasis Modulator

  • José Manuel Pérez de la Lastra,
  • Celia María Curieses Andrés,
  • Elena Bustamante Munguira,
  • Celia Andrés Juan and
  • Eduardo Pérez Lebeña

Silymarin (Silybum marianum (L.) Gaertn. extract) is a widely used botanical for liver disease, yet clinical results remain inconsistent. Most mechanistic work uses supraphysiological aglycones, whereas humans are exposed predominantly to phase II co...

(This article belongs to the Special Issue Feature Review Papers in Nutraceuticals)
  • Article
  • Open Access
1 Citations
1,559 Views
16 Pages

Pharmacokinetic Evaluation of Oleuropein from the Olive Tree (Olea europaea)

  • Pradeep Subedi,
  • Rocío Rivera Rodríguez,
  • Pariksha Thapa,
  • Daniel Lantvit and
  • Jeremy James Johnson

In this study, the pharmacokinetic (PK) characteristics of oleuropein present in the olive tree (Olea europaea) were determined. We developed and validated a highly sensitive ultra-performance liquid chromatography coupled with tandem mass spectromet...

  • Article
  • Open Access
1,344 Views
12 Pages

Dietary Intervention with Hibiscus sabdariffa L. Beverage Residue Attenuates Dyslipidemia and Hepatic Steatosis in Late-Stage Type 2 Diabetic Rats

  • Evelyn Regalado-Rentería,
  • Jesús E. Serna-Tenorio,
  • David G. García-Gutiérrez,
  • Rosalía Reynoso-Camacho and ,
  • Miriam A. Anaya-Loyola and
  • Iza F. Pérez-Ramírez
  • + 1 author+ 0 author

Roselle beverage residue (RBR), a by-product of Hibiscus sabdariffa L. processing, retains bioactive compounds, including soluble and insoluble dietary fiber and polyphenols. Its antihyperglycemic effect in type 2 diabetes mellitus (T2DM) has been pr...

  • Article
  • Open Access
1,999 Views
19 Pages

An Exploratory Study on a Multispecies Probiotic Formulation and Markers of Intestinal Health in Healthy People

  • Maria Cristina Verdenelli,
  • Maria Magdalena Coman,
  • Francesco Martino Carpi and
  • Stefania Silvi

This study aimed to explore the efficacy of oral supplementation with 11 probiotic strains, combined in the strain mix Probatech™ (Centro Sperimentale del Latte S.r.l Strada Provinciale per Merlino, 326839 Zelo Buon Persico (LO), Italy) and del...

  • Article
  • Open Access
1 Citations
1,423 Views
20 Pages

Comparative Study of Anti-Inflammatory and Antimicrobial Potentials of Natural By-Products

  • Na-Hyeon Park,
  • Ji-A Byeon,
  • Moon-Pil Jung,
  • Ju-Young Kim and ,
  • Seulki Yoon,
  • Gyu Hoon Kim,
  • Bo-Ae Kim and
  • Yong-Jin Kwon
  • + 3 authors+ 0 author

Natural by-products (NBPs), including pomace, peels, stems, and skins, account for over 50% of materials generated during fresh fruit processing. Most of these are discarded or landfilled, contributing to environmental pollution. NBPs are rich in bio...

(This article belongs to the Topic Functional Foods and Nutraceuticals in Health and Disease)
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Nutraceuticals - ISSN 1661-3821