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Nutraceuticals, Volume 3, Issue 2

June 2023 - 9 articles

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Articles (9)

  • Article
  • Open Access
10 Citations
7,847 Views
16 Pages

Designing Vitamin D3 Formulations: An In Vitro Investigation Using a Novel Micellar Delivery System

  • Min Du,
  • Chuck Chang,
  • Xin Zhang,
  • Yiming Zhang,
  • Melissa J. Radford,
  • Roland J. Gahler,
  • Yun Chai Kuo,
  • Simon Wood and
  • Julia Solnier

Vitamin D is an essential nutrient with important immunomodulatory properties. As a fat-soluble compound, Vitamin D (and its D3 form) is immiscible with water, which presents challenges to absorption. In an in vitro setting, the current study charact...

  • Feature Paper
  • Article
  • Open Access
3 Citations
5,908 Views
16 Pages

Purpose: To evaluate the association of CYP1A2 and ADORA2A gene polymorphisms, paraxanthine concentrations, and habitual caffeine (CAF) intake with respect to muscular performance after acute CAF supplementation. Methods: A total of 27 resistance-tra...

  • Article
  • Open Access
6,179 Views
12 Pages

Twelve Weeks of Oral L-Serine Supplementation Improves Glucose Tolerance, Reduces Visceral Fat Pads, and Reverses the mRNA Overexpression of Renal Injury Markers KIM-1, IL-6, and TNF-α in a Mouse Model of Obesity

  • Duyen Tran,
  • Muhammad Ishaq,
  • Cheng Yang,
  • Tauseef Ahmad,
  • Maurizio Ronci,
  • Mariachiara Zuccarini,
  • Stephen Myers,
  • Courtney McGowan,
  • Rajaraman Eri and
  • Darren C. Henstridge
  • + 2 authors

Comorbidities associated with obesity, including diabetes and kidney diseases, greatly increase mortality rates and healthcare costs in obese patients. Studies in animal models and clinical trials have demonstrated that L-serine supplementation is a...

  • Feature Paper
  • Article
  • Open Access
3,508 Views
12 Pages

Growing evidence indicates chronic low-grade systemic inflammation as a major pathophysiological mechanism of obesity. Systemic inflammation provokes an immune response in the brain through the activation of microglia that results in the development...

  • Article
  • Open Access
7 Citations
15,711 Views
16 Pages

Creatine Supplementation Alleviates Fatigue after Exercise through Anti-Inflammatory Action in Skeletal Muscle and Brain

  • Yuma Yokota,
  • Satoshi Yamada,
  • Daisuke Yamamoto,
  • Keita Kato,
  • Akihisa Morito and
  • Akiko Takaoka

Eccentric exercise induces muscle damage and inflammation, resulting in a state of reduced physical activity with muscle dysfunction and a feeling of tiredness after exercise. Creatine is known to act as an energy buffer, but it has also been suggest...

  • Communication
  • Open Access
1 Citations
3,457 Views
9 Pages

Behavioral and Biochemical Evaluation of Anti-Depressive and Oxidative Stress-Ameliorating Effects of Amber Extract in Adult Male ICR Mice

  • Sandra Somuah-Asante,
  • Mahmoud Ben Othman,
  • Reiko Takeda,
  • Kazuma Okazaki,
  • Marie Sekita and
  • Kazuichi Sakamoto

Amber, a plant resin, exhibits an anti-stress effect and is used in traditional medicine. Recently, it has been speculated that amber may possess an anti-depressive effect. However, there is no evidence to support this efficacy. Thus, this study inve...

  • Article
  • Open Access
9 Citations
4,068 Views
12 Pages

The purpose of this study was to investigate the loading properties of the non-psychoactive cannabidiol (CBD) in a new nanostructured lipid carrier (NLC), evaluating its bioaccessibility in gastric and intestinal simulated physiological media. CBD ha...

  • Article
  • Open Access
2 Citations
2,976 Views
14 Pages

Inspired by the potential functional activity of polyphenol compounds contained in raspberry (Rubus idaeus), we previously explored the effects of the cultivation environment and maturity on the polyphenolic profiles of raspberry leaves and fruits. H...

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Nutraceuticals - ISSN 1661-3821