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4 November 2025

A Mixed-Methods Evaluation of a Post-COVID-Condition Rehabilitation and Recovery Intervention Delivered in a Football Club Community Trust

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1
Human Performance and Health Laboratory, Birmingham City University, Birmingham B15 3TN, UK
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Burton Albion Community Trust, Burton-Upon-Trent DE13 0AR, UK
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Author to whom correspondence should be addressed.
This article belongs to the Section Exercise and Health-Related Quality of Life

Abstract

Aim: Post-COVID condition (PCC) is largely considered the biggest public health emergency in recent times. The role of exercise therapy in PCC is currently unknown, and evaluative studies are currently lacking in this area. This study therefore aimed to evaluate the effects of a football club community trust exercise rehabilitation programme on physical function and quality of life in individuals with PCC. Method: A mixed-methods retrospective design was employed, utilising a framework to assess the programme’s reach, effectiveness, adoption, implementation, and maintenance (RE-AIM). Quantitative data (questionnaires and physiological assessments) were collected at baseline, 6 weeks, and 12 weeks during the programme, and at 6 months post-intervention (n = 7). Qualitative data were gathered through semi-structured focus groups at week 12 (n = 7) and 12 months (n = 5) post-intervention. Quantitative data and qualitative data were analysed using repeated measures ANOVAs and thematic analysis, respectively. Results: The programme led to significant improvements in physical function, including increased six-minute walking distance (6MWT, p < 0.001), one-minute sit-to-stand repetitions (1MSST, p < 0.035), and lung function (spirometry; MIP: p = 0.048, MEP: p = 0.024). Participants also reported enhanced QoL (HRQoL-14, p = 0.004), reduced anxiety (GAD-7, p = 0.008) and depression (PHQ-9, p = 0.008), and increased confidence and self-efficacy. The programme was well-received, with participants valuing the supportive environment and personalised approach. Conclusions: Football community trust exercise rehabilitation programmes can effectively improve physical function and quality of life in individuals with PCC, offering a promising model for community-based rehabilitation. Further studies are needed with larger sample sizes to assess the scalability of similar programmes.

1. Introduction

The emergence of SARS-CoV-2 in 2019 significantly impacted global health, with long-term effects like post-COVID condition (PCC) affecting millions worldwide [,,]. PCC, also known as long COVID, presents a wide range of symptoms affecting multiple organ systems, making it a complex and challenging condition to manage. The National Institute for Health and Care Excellence (NICE) defines PCC as signs and symptoms that persist for more than 12 weeks after a SARS-CoV-2 infection, cannot be explained by another diagnosis, and often occur in clusters that fluctuate over time and affect various body systems []. This definition highlights the persistent and multifaceted nature of PCC, emphasising that it is not simply a prolonged version of the acute SARS-CoV-2 illness but a distinct condition with its unique challenges. Recent estimates suggest approximately 200 million people worldwide are experiencing PCC [], with 1.9 million cases in the United Kingdom (UK) alone []. Due to limited treatment options and the sheer number of individuals affected, PCC poses a potential crisis for the UK healthcare system, placing a significant burden on resources and necessitating innovative approaches to management and rehabilitation.
Contrary to initial assumptions that focussed primarily on respiratory symptoms, SARS-CoV-2 infection extends beyond the respiratory system, manifesting in over 200 symptoms across multiple organ systems [,]. The virus utilises the widespread angiotensin-converting enzyme 2 (ACE2) receptors for cellular entry, facilitating replication and triggering an inflammatory response characterised by immune cell activation and cytokine release []. This dysregulated immune response, often termed a “cytokine storm”, can inflict substantial damage on various organs, including the heart, lungs, kidneys, brain, and liver []. While research on the long-term sequelae is ongoing, accumulating evidence suggests potential for SARS-CoV-2 to induce lasting damage in these organs []. This damage can manifest in a range of chronic conditions, including but not limited to heart failure, arrhythmias, respiratory dysfunction, renal impairment, cognitive deficits, and neurological complications. The severity of these outcomes likely varies depending on individual factors such as initial infection severity, immune response, and pre-existing health conditions [] These findings underscore the importance of understanding the complex pathophysiology of PCC and tailoring treatment approaches accordingly.
To address the multifaceted nature of PCC, researchers and clinicians have explored various rehabilitation strategies, with a particular focus on exercise-based interventions. To date, research on exercise-based interventions has shown promise, with exercise-based programmes improving physical function, quality of life (QoL), and mental well-being [,,,,]. A systematic review and meta-analysis of 23 studies including 1579 individuals displayed positive effects on PCC-related symptoms including fatigue, dyspnoea, and depression, as well as improvements in overall QoL []. These interventions have included aerobic and resistance training, inspiratory muscle training, and digital/community-based programmes, highlighting the diverse approaches being explored to address the varied symptoms of PCC. Zheng et al. [] further supports the benefits of exercise in PCC recovery, demonstrating its potential to improve exercise capacity, lung function, and psychological well-being. However, limitations exist in the current research, including short follow-up periods, lack of personalised approaches, and the need to understand the underlying mechanisms of improvement. These limitations underscore the importance of continued research to refine rehabilitation strategies and optimise outcomes for individuals with PCC.
Perhaps a more alarming oversight is the lack of measurement of post-exertional symptom exacerbation (PESE) in PCC []. PESE is characterised by a worsening of symptoms after physical or mental exertion, posing a significant challenge for individuals with PCC and potentially hindering their recovery. This phenomenon emphasises the importance of tailoring exercise programmes to individual needs, gradually increasing intensity and duration, and using objective measures to monitor progress and prevent overexertion. Existing research on exercise interventions for PCC is limited by several factors. Many studies have short follow-up periods, failing to capture the long-term impacts and potential for symptom relapse, particularly concerning PESE []. Additionally, there is a lack of personalised approaches that cater to the diverse range of PCC symptoms, and the underlying mechanisms of reduced cardiorespiratory fitness remain unclear []. This makes it difficult to develop targeted rehabilitation strategies that address the specific needs of each individual with PCC. These limitations underscore the need for caution in interpreting existing evidence and highlight the importance of further research with longer follow-up periods, personalised approaches, and a focus on understanding the underlying mechanisms of action.
Given the positive impact of football-led health initiatives [,], independent community-led interventions, such as those offered by football club community trusts (FCCTs), may provide a positive model for PCC rehabilitation. These initiatives leverage the popularity and reach of football to engage individuals in health-promoting activities, potentially offering a novel approach to addressing the widespread impact of PCC. However, research in this area is lacking, and the effectiveness of FCCT-led programmes for PCC rehabilitation remains unknown. If successful, the use of FCCTs could offer a cost-effective and accessible method for individuals to access rehabilitation. It may also reduce the burden on traditional primary care and reliance on more costly services (i.e., in hospital care and rehabilitation services). This study therefore aims to evaluate the effects of an FCCT-led exercise rehabilitation programme on physical function and QoL in individuals with PCC. It is hypothesised that such a programme, tailored to the specific needs of individuals with PCC and incorporating strategies to mitigate the risk of PESE, will lead to improvements in mental and physical health outcomes.

2. Materials and Methods

The RE-AIM framework is a model utilised to help plan and evaluate the public health impact of interventions []. This study used a mixed-methods retrospective design to employ the RE-AIM framework to evaluate the Reach, Effectiveness, Adoption, Implementation, and Maintenance (RE-AIM) of a Post-COVID-Condition Rehabilitation and Recovery Programme (PCCRRP) in an FCCT (Table 1).
Table 1. Components of the RE-AIM framework in the context of the PCCRRP.

2.1. Intervention Context and Setting

Established in 2010, Burton Albion Community Trust (BACT) is a recognised FCCT organisation delivering successful community-based health interventions []. In response to the local need for support among people living with post-COVID condition (PLWPCC), participants were referred to an FCCT PCCRRP designed to improve outcomes for service users diagnosed with PCC. The PCC clinic referred appropriately clinician-assessed service users into a 12-week community-led, exercise and psychosocial support intervention. Following the PCC clinic assessment, the need for rehabilitation was established when symptoms were complex in nature and caused significant functional impairment, thus requiring a supervised and structured multidisciplinary approach to recovery. Participants were then recruited from BACT by Birmingham City University (BCU) to participate in this study.
The PCCRRP pilot employed a 12-week personalised exercise referral scheme (ERS) delivered twice weekly in a community setting. PCCRRP plans were co-designed with participants and BACT and typically included supervised low to moderate intensity exercise sessions consisting of a combination of aerobic, stability and mobility, and strength-based exercises. PCCRRP plans were created and overseen by BACT personnel with level 7 qualifications in sport and exercise science and health and physical activity. Moreover, BACT personnel had experience managing patients with multiple health conditions and comorbidities. Extreme caution was applied prior to commencing any exercise session. Before initiating each gym-based exercise session, participants were screened for PEM and ME/CFS [,]. Any participant displaying signs of post-exertional malaise (PEM) and Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) would discontinue the PCCRRP and be referred to primary care. Additionally, resting heart rate (RHR), blood pressure (BP), and arterial oxygen concentration levels (SPO2) were measured and recorded prior to exercise. All gym-based exercise was conducted in-person in strictly controlled gym environments. The modified BORG scale (mBORG) [] was utilised to measure the perceived exertion level of exercise throughout participation in the full exercise session. Participants could contact the referring primary care provider at any point during the 12 weeks. Throughout the intervention period, participation was free of charge. Participants received biweekly contact, both at gym-based sessions and additionally through virtual (Microsoft Teams) or phone contact for additional advice and guidance if required. For those who did not attend (DNA), three attempted calls were made within 48 h. If there was no response or the participant did not wish to be part of or continue the programme, the primary care provider referrer would be informed.

2.2. Participants and Procedures

All seven adults were adults aged 18 years or older and had undergone a medical assessment at the PCC clinic by their primary care provider (PCP) (Table 2). The PCP then referred the patient to BACT. Participants included in this project were identified by PCPs as requiring support with rehabilitation as part of PCC assessment pathways. Upon referral to BACT, prior to initial interviews, baseline questionnaires, and physiological assessments, service users were requested to provide consent for their data to be used for research purposes via a project participant information sheet and consent form. Additionally, they were invited to participate in focus groups (FGs). The lead author (SR) and co-authors (LG and IK) facilitated the FGs. Only the data of those who completed and returned consent forms were included in this study. All participants were provided with comprehensive details of the project, including its rationale, methodology, potential benefits, and potential risks, prior to providing informed consent. Furthermore, all participants understood that participation was voluntary and that there were no consequences for choosing not to participate and that they could discontinue participation if they wished to. Ethical approval for the study was obtained through BCU Health, Education and Life Sciences Faculty Academic Ethics Committee (ID#10203). All participants who enrolled into the study completed the study in full and a summary of procedures can be seen in Figure 1.
Table 2. Summary of demographic profile at baseline. Age is presented as mean ± standard deviation, and other variables as the total number and percentage of total sample.
Figure 1. Timeline displaying the outcome measures of PLWPCC in the PCCRRP. Key: Body mass (BM). Resting heart rate (RHR). Arterial oxygen concentration (SPO2). Blood pressure (BP). Lung function: muscle inspiratory pressure (MIP). Muscle expiratory pressure (MEP). Post-exertional malaise (PEM). Six-minute walk (6MW). One-minute sit to stand (1MSS). Dyspnoea (modified Borg scale 1–10). Health-Related Quality of Life (HRQOL-14). General anxiety disorder (GAD7). Physical Health Questionnaire (PHQ9). Short Active Lives (SALS).
The inclusion criteria for the Post-COVID-Condition Rehabilitation and Recovery Program (PCCRRP) service users were a previous diagnosis of SARS-CoV-2 with a current negative test result, being 18 years of age or older, the ability to walk independently for at least 20 metres, and having access to transportation to the gym-based setting. Exclusion criteria included active SARS-CoV-2 symptoms (positive test), already receiving community-based rehabilitation, a diagnosis of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS), or a formal diagnosis of post-traumatic stress disorder (PTSD), clinically significant anxiety, or depression.

2.3. Clinical and Physiological Measures

Body mass (BM) was measured at baseline, 6 weeks, 12 weeks, and 6 months using Seca 813 digital flat scales (Seca, Birmingham, UK). Resting heart rate (RHR) and blood pressure (BP) were measured at the same time points using the Omron M3 Comfort blood pressure monitor (Omron, Milton Keynes, UK) []. Blood oxygen saturation (SpO2) was also measured at these intervals using an NHS-approved PX-100 EU Salter fingertip pulse oximeter (Salter, Manchester, UK) []. Breathing difficulty was assessed at baseline, 6 weeks, 12 weeks, and 6 months using the modified Borg scale (mBorg) [].
Lung function, specifically maximal inspiratory pressure (MIP) and maximal expiratory pressure (MEP), was measured at baseline, 6 weeks, 12 weeks, and 6 months using the CareFusion MicroRPM respiratory pressure spirometer (CareFusion, San Diego, CA, USA) []. These measures were employed as a marker of improvement from the rehabilitation programme. No specific respiratory training was conducted using these devices. The DePaul Post-Exertional Malaise Questionnaire (DPEMQ) was administered before each exercise session to assess post-exertional malaise (PEM) and determine exercise suitability []. Physical activity levels were assessed at baseline, 6 weeks, 12 weeks, and 6 months using the Short Active Lives Questionnaire (SALS) [].
To evaluate lower-body strength and exercise capacity, the one-minute sit-to-stand test (1MSST) and the six-minute walk test (6MWT) were conducted at baseline, 6 weeks, 12 weeks, and 6 months []. Perceived exertion during the 6MWT was measured using the mBorg scale []. Mental well-being was assessed at the same time points using the Generalised Anxiety Disorder 7 (GAD-7) [,], Patient Health Questionnaire 9 (PHQ-9) [,], and Short Warwick-Edinburgh Mental Well-being Scale (SWEMWBS) [] to evaluate anxiety, depression, and mental well-being, respectively. Lastly, the CDC HRQOL-14 was used to evaluate health-related quality of life (HRQoL) at baseline, 6 weeks, 12 weeks, and 6 months [].

2.4. Focus Groups

FG discussions were conducted at week 12 and 12 months post-intervention to gather insights from participants regarding their lived experiences with the PCCRRP and its impact (Supplementary Material). The RE-AIM framework served as the theoretical underpinning for the evaluation, guiding the FG discussions’ structure and content. The interview schedule for the FGs was crafted to align with the RE-AIM framework’s components. This approach ensured that the discussions focussed on the programme’s reach, effectiveness, adoption, implementation, and maintenance.
FGs have been widely employed in previous research investigating participant experiences in football-led health improvement interventions, effectively capturing both the implementation component of RE-AIM [] and key characteristics such as the Premier League Men’s Health Evaluation and the Fit Red’s Men’s Health Evaluation [,]. These methods offer an inclusive, efficient, and convenient approach to gathering information on participant experiences and their engagement with interventions.
Each FG consisted of a sex-mixed composition. Seven participants attended the 12-week FG, while five attended the 12-month FG. The FGs were both held at Burton Albion Football Community Centre lasting approximately 90 min and were digitally recorded. Guided by the principle of reflexivity, the thematic analysis focussed on the trustworthiness and authenticity of findings []. The lead author (SR) and co-authors (LG and IK) served as note-takers, recording key themes and sub-themes emerging from the FG discussions. After each session, these themes and sub-themes were verbally presented back to the participants for confirmation and clarification, ensuring the accuracy and authenticity of the captured information. This participant-led verification process ensured the authenticity and accuracy of the acquired information. Thus, demonstrating participant experience and privilege of voice over the researchers’ own perspectives was a key part of the design of the research process. Such a deliberate strategy enhances the rigour and validity of the thematic analysis [].
The lead researcher (SR) cultivated rapport with the participants throughout the 12-week intervention period, fostering a sense of familiarity and trust, which was vital for facilitating open and honest dialogue. This pre-existing connection was established during the baseline consultation and PCCRRP delivery, as well as during recruitment and participation in the FGs. Similarly, existing relationships among participants further enhanced engagement and interaction during the discussions. Additionally, it highlights the positive impact of these connections on participant engagement and interaction and consequently helps generate meaningful results.

2.5. Data Reduction and Analysis

Upon completion, all questionnaires were entered into a password-protected Excel spreadsheet. Coded identification numbers were used for participant anonymity. The data were then transferred to SPSS (v29 for Windows, IBM Corp., Chicago, IL, USA) for cleaning and analysis.
In accordance with Rutherford et al. [] a “completers only” approach was adopted to analyse the outcome data. Completers were defined as individuals who provided usable questionnaire data at baseline, 6 weeks, 12 weeks, and 6 months. This approach aligns with that of Rutherford et al. [] which provides the most effective method for determining changes in physical activity and HRQOL over time, considering the constraints of the data collection method.
All data were assessed for normality using the Shapiro–Wilk test and visually inspected using boxplots. Physiological and questionnaire data were analysed using repeated measures analysis of variance (ANOVA) over changes in time between baseline, 6 weeks, 12 weeks, and 6 months. For ANOVA interactions and main effects, the effect size is reported as partial eta squared (pη2). The assumption of normal distribution was violated for HRQoL and SALS, therefore the Friedman test, a non-parametric alternative, was conducted as the alternative test. Between changes in time, effect sizes (g) were calculated by dividing mean difference by the pooled standard deviation (SD) [,,] and applying Hedge’s g bias correction to account for the small sample size [,,]. These effect sizes were categorised as trivial (≤0.2), small (0.2–0.49), moderate (0.5–0.79), or large (≥0.8) []. Effect sizes for non-normally distributed data (r) were calculated from z/√n, with 0.10, 0.24, and 0.37 considered as small, medium, and large, respectively []. Statistical data are presented with 95% confidence intervals to indicate the precision of the estimated values. All data were analysed using SPSS (v29 for Windows, IBM Corp., Chicago, IL, USA) and statistical significance was determined as p < 0.05.
FGs were administered at week 12 and 12 months, respectively. Following the FGs, the recorded audio files underwent verbatim transcription by the lead author (SR) and co-author (SL). Guided by the principle of reflexivity [], the thematic analysis was designed to elicit authenticity in its findings. Thematic analysis utilised the process of familiarisation, coding, generating themes, reviewing themes, defining and naming themes, and writing up the results []. For the interview data, after transcription and immersion in the transcripts, coding revealed intriguing features within the data. These features were subsequently grouped into coherent themes using the RE-AIM framework components. A visual map was hand-crafted to illustrate the themes and their interrelationships. Four researchers (LG, IK, AH, and AK) met to refine the specifics of the themes and to generate clear definitions and names for them, which were then shared with the lead author (SR). This approach has commonly been used in the investigation of football-led health improvement programmes []. A collaborative approach to data collection was utilised to mitigate any potential for researcher bias.
Following both quantitative and qualitative analysis, a cross-validation via triangulation was conducted to determine convergent or divergent narratives. The qualitative data was then seen as complementarity to the quantitative date to help answer why and how results occurred. This was seen as beneficial for this study as most studies investigating exercise and PCC had isolated methods (i.e., either quantitative or qualitative methods).

3. Results and Discussion

Results are presented detailing the quantitative and qualitative results separately. The discussion then integrates these findings, presenting interpretation in a combined manner, providing a comprehensive understanding of the research.

3.1. Demographics

A summary of demographics can be seen in Table 2 with the n number and percentage distribution reported.

3.2. Exercise Variables

Results showed a significant increase in the distance covered during the 6MW throughout the study (p < 0.001; Pη2 = 0.969). This improvement was significant and substantial at all time points except for between 12 weeks and 6 months. Between the baseline vs. week 6, a large effect size (ES = 3.86, 95% CI = 5.77, 1.95) was observed, with a significant increase (p < 0.001; CI = 516.7, 369) in walking distance by week 6. Significant improvements with large effect sizes (p = <0.001; CI = 723.9, 556.1) (ES =5.2, 955 CI = 7.56, 2.83), (p = <0.001; CI = 893.8, 532) (ES = 5.83, 95% CI = 8.42, 3.24) were observed at week 12 and 6 months compared to the baseline, respectively. While significant differences were observed between all time points, with the exception of week 12 vs. 6 months (p = 0.699), large effect sizes were present throughout; week 6 vs. week 12 (p < 0.001; CI = 280.5, 113.8) (ES = 2.62, 95% CI = 4.16, 1.08) and week 6 vs. 6 months (p = 0.002; CI = 415.3, 124.7) (ES =3.69, 95% CI = 5.55, 1.83).
The study displayed a significant increase in the number of 1MSS repetitions performed throughout the study (p < 0.035; Pη2 = 0.373). This improvement was most evident in the early stages. Between baseline vs. week 6, a significant increase (p = 0.010; CI = 14, 2.3) with a large effect size (ES = 1.51, 95% CI = 2.79, 0.23) was observed, suggesting a substantial increase in 1MSS repetitions by week 6. The difference between baseline vs. week 12, while significant (p = 0.003; CI = 20.1, 5.3), had only a moderate effect size (ES = 0.71, 95% CI = 1.88, 0.45) compared to baseline vs. week 6. No significant differences were found at later time points (p > 0.05). However, baseline vs. 6 months displayed a large effect size (ES = 1.45, 95% CI = 2.73, 0.18), suggesting a significant increase in 1MSS repetitions compared to baseline.

3.3. Physiological Variables

Results showed a significant increase in MIP scores over time (p = 0.048; Pη2 = 0.349). This increase was most evident between baseline and week 6 (p = 0.018; CI = 44.9, 4.8), with a moderate effect size (ES= 0.73, 95% CI = 1.09, 0.44). No significant differences were observed at later time points (p > 0.05). Results showed a significant improvement in MEP scores over time (p = 0.024; Pη2 = 0.463). While post hoc analysis did not detect significant differences between specific time points (p > 0.05), a moderate effect size was observed between baseline and week 6 (ES= 0.74, 95% CI = 1.91, 0.93). No significant differences were observed at later time points (p > 0.05). Results show decreased dyspnoea across the study (p = 0.341, Pη2 = 0.166). A significant decrease in dyspnoea was observed between baseline and week 6 (p = 0.019; CI = 0.334, 3.23) with a large effect size (ES = 1.14, 95% CI = 0.08, 2.36). No significant differences were found between later time points (p >0.05). No significant differences were observed in BM across the duration of the study (p = 0.149; Pη2 = 0.307). No significant differences were observed in RHR (p = 0.179; Pη2 = 0.249) or SPO2 (p = 0.273; Pη2 = 0.194) across the duration of the study. No significant differences were observed in systolic BP (p =0.503; Pη2 = 0.108) or diastolic BP (p =0.963; Pη2 = 0.006) across the duration of the study.

3.4. Questionnaire Variables

The results showed that a significant increase in SALS scores was observed across the study (χ2(2) = 6.231, p = 0.044). The difference between baseline vs. week 6, although not significant (p = 0.18), had a large effect size (ES = 0.82, 95% CI = 2, 0.86) which suggests an initial increase in activity by week 6. For baseline vs. week 12, a similar pattern emerged. No significant differences were observed (p = 0.249); however, its large effect size (ES = 0.87, 95% CI = 2.05, 0.32) points towards a substantial activity increase by week 12. No other significant differences were observed across later time points (p > 0.05).
Results show a significant impact on GAD-7 scores, indicating a reduction in anxiety (p = 0.008; Pη2 = 0.549). While post hoc analysis did not reveal significant differences between specific time points (p > 0.05), effect sizes displayed a large effect size (ES = 1.54, 95% CI: 0.25, 2.83) between baseline and week 6, indicating a substantial initial decrease in anxiety. No significant differences were observed at later time points (p > 0.05).
Results show a significant difference in PH-9 scores across the study (p = 0.008; Pη2 = 0.536). Despite no significant differences between specific time points upon further analysis (p > 0.05), large effect sizes were observed between baseline and week 6 (ES = 1.21, 95% CI = 0.02, 2.44) and baseline and week 12 (ES = 1.08, 95% CI = 0.13, 2.30), respectively, indicating substantial improvements in depressive symptoms early in the intervention. No significant differences were observed at later time points (p > 0.05).
Results show a significant increase in SWEMWBS scores, indicating improved mental well-being across the study (p = 0.001; Pη2 = 0.624). This improvement was evident at all time points compared to baseline. Significant increases with large effect sizes (p = 0.017; CI = 10, 1.45) (ES = 1.09, 95% CI = 2.3, 0.13) (p = 0.014; CI = 12.2, 2.1) (ES = 1.41, 95% CI = 2.67, 0.15) (p = 0.013; CI = 14.1, 2.5) (ES= 1.41, 95% CI = 2.67, 0.15) were observed between baseline and all follow-up points at weeks 6 and 12 and 6 months, respectively. While the difference between week 6 and 6 months was significant (p = 0.042; CI = 5.01, 0.133), the effect size between week 6 and 6 months (ES = 0.7, 95% CI = 1.82, 0.5) was moderate compared to earlier time points. No significant differences were observed at later time points (p > 0.05).
Results show a significant improvement in participants’ QoL across the study duration (p = 0.004; Pη2 = 0.702). This was supported by positive changes reported on the HRQoL-14 across various dimensions (Table 3), including self-care, work or recreation, pain, mood, sleep quality, and energy levels. Significant improvements with large effect sizes (p = 0.009; CI = 5.6, 32.1) (ES = 1.36, 95% CI: 0.10, 2.62) (p = 0.004; CI = 8.2, 32.3) (ES = 1.63, 95% CI = 0.32, 2.93) (p = 0.004; CI = 8.9, 34.2) (ES = 1.69, 0.37, 3) were observed between baseline and all follow-up points, weeks 6 and 12 and 6 months, respectively. No significant differences were found between later time points (p > 0.05).
Table 3. The number (%) of PLWPCC respondents reporting HRQoL-14 activity limitations at baseline, 6 weeks, 12 weeks, and 6 months.

3.5. Focus Group at Week 12

3.5.1. Reach

Seven participants took part in the PCCRRP (n = 5 female, n = 2 male). Participants expressed being drawn to the FCCT setting due to it feeling less clinical than a traditional GP surgery. However, others stated their desperation to improve their health and well-being was such that they were willing to try anything to obtain the help and support they felt they needed.

3.5.2. Effectiveness

The positive changes observed in QoL scores were supported by qualitative data from the FGs. The qualitative data presented in Table 4 and Table 5 suggests that participation in the PCCRRP had a positive impact on participants’ QoL. These findings are consistent with those reported previously in the literature [,,,]. A recurrent theme identified throughout the FG discussions was the concept of a “light at the end of the tunnel,” signifying a sense of hope, in addition to “feeling normal”, which related to regaining a sense of pre-illness functioning. There was a strong emphasis on the participants’ desire to return to their usual activities and capabilities and, in some instances, beyond their original capabilities pre-diagnosis, consistent with findings in an FCCT setting by Rutherford et al. [] with people living with cancer. Participants provided detailed accounts in Table 6 of how the PCCRRP had improved their fitness, mental well-being, confidence and self-efficacy, and ability to return to pre-diagnosis levels of function, including work and exercise participation.
Table 4. The number of participants (%) reporting HRQoL-14 Healthy Days symptoms, and number of days on which symptoms were experienced, reported at baseline, 6 weeks, 12 weeks, and 6 months by PLWPCC respondents.
Table 5. Overall effectiveness themes, sub-themes, and participant quotes related to their experience of the PCCRRP.
Table 6. Overall adoption themes, sub-themes, and participant quotes related to their experience of PCCRRP.

3.5.3. Adoption

The themes relating to the profiles of participants who engaged in the PCCRRP including their physical activity, health status, and reported barriers and facilitators are presented in Table 6. Participants reported a significant factor in their improvement was the PCCRRP focusing on personalised exercise plans. Participants expressed that the tailored exercise plans empowered them to manage their symptoms and helped them to regain a sense of control over their lives. Furthermore, this had a positive impact on their emotional well-being, which led to increased confidence and a reduction in anxiety.

3.5.4. Implementation

Generally, participants were happy with how the implementation of the programme ensued (Table 7). Some also reported that their feelings of isolation were reduced through engaging with the programme. One key factor was the “friendly” faces of the staff who delivered the programme. This potentially highlights the need for suitably qualified staff to deliver an exercise programme.
Table 7. Overall implementation themes, sub-themes, and participant quotes related to their experience of the PCCRRP.

3.5.5. Maintenance

Participants reported that more social spaces for patients with PCC would have enhanced their experience in the programme (Table 8). The program was run so that the majority of time was spent on a one-on-one basis between trainers and participants. There were also some concerns raised about the post-program maintenance of exercise given that, once the program was complete, the participants were not offered any further support for their rehabilitation. This presents some potential for future research to implement related changes in order to maximise this programme’s suitability for PCC patients.
Table 8. Overall maintenance themes, sub-themes, and participant quotes related to their experience of a PCCRRP.

3.6. Focus Group at 12 Months

Participants expressed feelings of embarrassment about their illness and that difficulty explaining often invisible symptoms led to social withdrawal and frustration. Moreover, they emphasised their desire to improve but felt unheard and dismissed by those who questioned the reality of their condition. These findings are consistent with those reported by Owen, Ashton, and Skipper et al. []. These elements paint a picture of individuals struggling with a debilitating condition that affects not just their health, but also their ability to connect with others, fostering a sense of isolation and frustration aligned with findings reported by Gerlis et al. []. Participants discussed the disruption of their usual roles, leading to a negative impact on their family lives. The inability to fulfil their responsibilities, coupled with increased frustration and exhaustion, created a sense of disarray, and impacted everyone’s well-being. The described sense of disarray and sense of being a burden on partners resonates with the findings of Gerlis et al. [] and Daynes et al. [], emphasising the broader social and familial consequences of PCC. Furthermore, the frustration stemming from the inability to fulfil responsibilities and comparison with milder cases echoes the experiences shared by participants in Gerlis et al. [], who expressed surprise at the severity and duration of their symptoms. The loss of independence and normality, with basic tasks becoming impossible, led to an increased reliance on their partners and other family members. This shift in the marital dynamic, coupled with the feeling of being a burden, suggests a potential strain on the relationship. These experiences showcase the far-reaching effects of PCC. The illness not only impacts the individual’s health, but also their social life, mental well-being, and family dynamics. However, as participants’ symptoms gradually improved, they displayed an increase in their confidence by week 6. An important component is that at the 12-month time point, the positive effects of the PCCRRP were still being felt. Generally, participants were “back to normal” at 12 months and cited both physical and mental health rewards (Table 9). This is unique of the current study and suggests that the physiological changes reported in this study via quantitative methodology assisted with these long-term benefits.
Table 9. Overall effectiveness themes, sub-themes, and participant quotes related to their experience of the PCCRRP at 12 months.
For PCCRRP improvement, participants emphasised the importance of self-management tools, including information packets with symptom management strategies and prescribed exercise exit plans for home or local gyms. Establishing routines for exercise, healthy eating, and self-care activities were also highlighted as crucial for sustained recovery. Furthermore, the FG also revealed valuable insights for programme optimisation. Participants expressed a desire for a supportive network fostered through social media groups, meetups, or group exercise sessions with multiple instructors. This aligns with the findings of Gerlis et al. [], who emphasised the value of shared experiences and peer support during rehabilitation, highlighting the importance of social connection in the recovery process. Moreover, a hybrid model with both group and individual exercise sessions was suggested for increased flexibility. Additionally, participants emphasised the need for advocacy with employers to facilitate time off work for exercise, recognising its importance for recovery.

3.6.1. Reach

Five participants (n = 3 female, 2 male) took part in the PCCRRP 12-month FG.
By incorporating a wider range of support for cognitive difficulties, the PCCRRP can empower patients to regain control of their daily lives and improve their overall well-being. However, it is important to acknowledge that the needs of PCC patients are diverse, and the pilot programme will require adjustments to address a wider range of challenges. Previous studies [,,] acknowledge the diverse needs of patients recovering from PCC and emphasise the importance of tailoring rehabilitation programmes to individual needs and abilities. Additionally, as highlighted by multiple participants who felt the programme would have been more helpful “a lot sooner” after their diagnosis, ensuring early intervention through increased programme availability and outreach efforts is crucial. This aligns with previous evidence which emphasise the benefits of starting rehabilitation early after hospital discharge or the onset of LC symptoms []. The positive experiences shared by participants in Table 10 highlight the potential for such programmes to make a significant impact. Twelve months later, all participants continually expressed a “light at the end of the tunnel” in respect of their recovery. They also provided emphasis on proactive strategies like going out for walks and connecting with others highlight the potential of such programmes to make a significant impact.
Table 10. Overall adoption themes, sub-themes, and participant quotes related to their experience of the PCCRRP at 12 months.

3.6.2. Effectiveness

Table 10 displays improvements in various aspects of physical health and mental health, including reduced anxiety, depression, and fear, and increased confidence and social interaction after participating in the programme. Participants expressed how utilising physical activity and improving overall fitness helped contribute to a more positive mental outlook. Tangible gains in physical fitness and strength helped to foster a sense of improved confidence and autonomy that had a positive improvement on their QoL. These findings align with previous studies [,,,,] which also reported similar improvements following exercise-based rehabilitation programmes, except the current study also offers context through the focus group design. Some participants experienced improved cognitive function and reduced brain fog after the programme. While some maintained physical activity after the programme, others struggled with motivation and consistency. Indeed, some experienced challenges in maintaining a fitness routine, particularly when faced with external disruptions. This highlights the importance of finding a routine that works and the negative consequences when it is not adhered too. Furthermore, the FG discussions revealed a compelling need for more comprehensive PCCRRPs. Beyond physical limitations, participants described significant mental and emotional challenges, highlighting the need for a holistic approach. One participant powerfully described their desperation due to a lack of available support and information, emphasising the urgency of making resources more accessible (Table 11). This pilot programme might be effective for some, but its impact could be significantly amplified by ensuring wider availability and outreach efforts to reach more patients in need. Generally, the FG discussions underscored the importance of hope, empowerment, access to information, and social connection, similar to findings previously reported Rutherford et al. [] for PLWPCC. While the programme has demonstrably improved the lives of participants, there is room for improvement to ensure it reaches a wider population and offers a more holistic approach that addresses the multifaceted challenges of PCC.
Table 11. Overall implementation themes, sub-themes, and participant quotes related to their experience of the PCCRRP at 12 months.

3.6.3. Maintenance

The 12-month FG displays the multifaceted challenges of PCC. The FG yielded a rich tapestry of experiences, highlighting the complex and far-reaching impacts of the illness. While the rehabilitation pilot programme might be effective in some areas, the participants’ narratives suggest a need for a more comprehensive approach. Table 12 portrays findings which underscore the importance of acknowledging the diverse needs of PCC patients. Rehabilitation programmes can be more effective by incorporating support for mental health, cognitive difficulties, daily routine management, and overcoming logistical challenges. By equipping patients with a wider range of tools and strategies, these programmes can empower them to manage their symptoms, improve their overall well-being, and adjust to their new normal (Table 12).
Table 12. Overall maintenance themes, sub-themes, and participant quotes related to their experience of the PCCRRP at 12 months.

3.7. Summary of Findings

A community-based ERS intervention, the PCCRRP, effectively improved physical function and QoL in individuals with PCC. The programme, delivered by an FCCT, was evaluated using the RE-AIM framework to provide comprehensive insights into its reach, effectiveness, adoption, implementation, and maintenance. The key findings were (1) Rapid and sustained improvement: The PCCRRP demonstrated significant positive impacts within the initial six weeks, with large effect sizes observed across most outcome measures. For those adhering to the programme (adopters), these improvements in PA levels, fatigue, QoL, and confidence in daily living were sustained over a 12-month period. (2) Holistic benefits: Beyond physical improvements, participants reported significant positive changes in their social lives and mental well-being. (3) Addressing barriers to participation: The programme successfully alleviated anxieties and fears associated with PA, primarily due to the safe and supportive environment fostered by staff and peers who understood the participants’ condition. (4) Shared experience: An unexpected finding was that participants highly valued the opportunity to share their experiences with others in a similar situation during the FGs, highlighting the importance of social support in recovery from PCC.
These findings align with previous research in a similar FCCT setting by Rutherford et al. [], reinforcing the effectiveness of community-based interventions for individuals with chronic health conditions. Moreover, the present study’s mixed-methods evaluation may effectively support FCCT report outcomes to justify future funding. Indeed, the present study further contributes to a growing body of evidence on the potential benefits of exercise and rehabilitation for individuals with PCC, demonstrating exercise was well tolerated by participants with no reports of incidence of PEM, ME/CFS, or PESE as previously reported in the literature [,,]. Markedly, although the present study demonstrated significant positive impacts within the initial six weeks, a key feature of the study is the longitudinal design which provides valuable insights into the sustainability of the intervention’s benefits over a chronic timeframe. In addition, the current study is uniquely placed in that it blended both quantitative and qualitative outcomes to the rehabilitation programme, which is not the case across the PCC literature currently. Consistent with our results, Wright et al. [] found that LC is linked to decreased PA and loss of independence. However, contrary to our findings, Wright et al. [] reported that most participants experienced a worsening of LC symptoms with PA. In contrast, the present study found no exacerbation of PCC symptoms, which is likely due to the personalised rehabilitation approach.
Gerlis et al. [] reported improvements in physical symptoms (breathlessness and fatigue) and emotional well-being (confidence and reduced worry) through a rehabilitation programme. The current study is unique in that it can be inferred from the findings that physical improvements (quantitative variables) were intertwined with the psychological improvements (qualitative focus group feedback) reported from the participants. For example, a significant improvement in respiratory muscle function was reported by participants, and this reflected the gradual return to physical activity and exercise of the participants reported in the focus groups. Furthermore, the importance of the safe and supportive environment provided by the PCCRRP was noted. Moreover, the staff’s empathy and the camaraderie among peers were highly valued. The programme offered validation and assurance for individuals experiencing ongoing SARS-CoV-2 symptoms, which were often misunderstood or misbelieved by others. This finding aligns with more recent research [,] reporting participants feel unheard, dismissed, or poorly informed, with reports of medical gaslighting and inadequate support received. The opportunity to share experiences and reflections with others in a similar situation was considered invaluable. The positive impact on physical and mental well-being reported by participants is consistent with the current study.
To optimise the long-term benefits of programmes like the PCCRRP, future research should consider several key areas. In terms of self-management, comprehensive guides are provided at the programme’s start covering topics such as fatigue, breathlessness, sleep, cognitive issues, exercise routines, healthy eating, mindfulness, and cognitive training. Research should analyse the effectiveness of these specific strategies in improving long-term outcomes. A daily routine, encourages regular physical activity, self-care, and the use of reminders/note-taking tools; it is recommended that researchers should investigate the impact of adherence to these routines on long-term symptom management and well-being. Regarding social support, which facilitates connections through online groups or physical meetups, research should evaluate the effectiveness of different models, such as online versus in-person, on long-term outcomes. Whilst the current study provides support through an individualised approach to rehabilitation, it is important for future research to consider how this can be scaled up to be applicable to more people whilst still capturing quantitative and qualitative outcomes. We acknowledge that this method of rehabilitation is likely costly, so alternatives would be attractive. Nonetheless, it is important to establish if more cost-effective methods lead to similar improvements, and they would only be worth it if so. The proposed research recommendations can be categorised based on their cost-effectiveness. Highly cost-effective options leverage existing programme data or resources, such as analysing the programme’s initial phase or the effectiveness of self-management strategies. Moderately cost-effective research may involve additional data analysis or potentially require small-scale studies to explore areas like the impact of programme structure or daily routine adherence. Research with lower cost-effectiveness signifies a greater need for additional resources. This could involve extending the programme duration, implementing more intensive interventions, or developing highly personalised programme adjustments, all of which may require increased staff time or programme modifications.

3.8. Strengths and Limitations

A key strength of this study is its mixed-methods approach to evaluating a community-based intervention, which provides in-depth participant accounts to enhance understanding of outcome data. Furthermore, the study’s longitudinal design, with data collected at baseline, 6 weeks, 12 weeks, 6 months, and 12 months, provides valuable insights into the sustainability of the intervention’s benefits over time. This allowed the researchers to assess the long-term effectiveness and maintenance of the PCCRRP on participants’ physical (fatigue) and psychological function. Moreover, utilising the RE-AIM framework throughout the evaluation process allowed for a comprehensive investigation of the intervention’s effectiveness and implementation, elucidating the factors that contributed to its success and areas that could be improved. Additionally, we were able to demonstrate the efficacy of a community-based intervention for improving the physical and mental function of people with PCC. This research may also provide commissioners and policymakers with detailed information to support future funding applications and resource allocation. A key aspect to highlight is the high frequency of support that was provided from exercise science and physiology staff. These staff were trained in most cases to an undergraduate or post-graduate level, which may necessitate the need for similarly qualified staff in other studies of programs such as this one.
Some limitations must be acknowledged for the current study. We recognise that the instruments used in the studies were not specific to PCC and, instead, are validated against the general population. Whilst not specifically validated in PCC, the instruments still offer value, and in the absence of PCC-specific questionnaires, are still applicable in the study. We also acknowledge the need for further investigation with a larger sample size. A larger sample size improves the generalisability of the findings and statistical procedures (i.e., increase statistical power), making them more applicable to a wider population. This study served as a pilot investigation to explore PLWPCC. The homogeneity of our sample, predominantly comprising white British participants, limits the generalisability of our findings to more diverse populations. Additionally, we acknowledge the absence of a control group. Therefore, we cannot directly attribute all of the observed benefits to the PCCRRP or understand the influence of factors such as support from previous rehabilitation specialists or social interaction with other participants.

4. Conclusions

The present study utilised a mixed-methods methodology to investigate the effects of an exercise rehabilitation and recovery programme on the physical function and QoL of individuals with PCC. The results of the present study demonstrate that the PCCRRP was effective in providing PLWPCC with a positive impact on their physical (fatigue) and psychological function, with some returning to levels they previously experienced before their PCC diagnosis. This is a unique finding given that positive outcomes were still being felt at the 12-month focus group. This pilot study offers in-depth recommendations for future studies, where the scalability of this programme could be an attractive option for fellow FCCTs or healthcare settings. It is worth noting that programmes such as the current study will not be the most cost-effective option but do provide significant positive outcomes that may warrant higher prices. Furthermore, these findings suggest that fostering a supportive community and adapting programmes to individual needs are key elements for long-term success in PCC rehabilitation.

Supplementary Materials

The following supporting information can be downloaded at: https://www.mdpi.com/article/10.3390/ijerph22111672/s1, File S1: 12-week focus group questions.

Author Contributions

Conceptualization, S.R.; methodology, S.R., L.A.G. and I.K.; software, S.R.; validation, S.R., formal analysis, S.R.; investigation, S.R. and S.L.; resources, S.R.; data curation, S.R.; writing—original draft preparation, S.R.; writing—review and editing, S.R., L.A.G., A.J.H., A.L.K. and I.K.; visualisation, S.R.; supervision, L.A.G.; project administration, S.R. and L.A.G. All authors have read and agreed to the published version of the manuscript.

Funding

This research received no external funding.

Institutional Review Board Statement

The study was conducted in accordance with ethical approval granted by the BCU Health, Education and Life Sciences Faculty Academic Ethics Committee (ID#10203, 1 March 2022).

Data Availability Statement

The data presented in this study are available on request from the corresponding author due to legal restrictions.

Conflicts of Interest

The authors declare no conflicts of interest.

References

  1. National Institute for Health and Care Excellence (NICE). Post-COVID-Condition Syndrome (Long COVID); National Institute for Health and Care Excellence: London, UK, 2020. [Google Scholar]
  2. Chen, C.; Spencer, R.; Xu, S.; Haupert, L.Z. Global prevalence of post-acute sequelae of Covid-19 (PASC) or long covid: A meta-analysis and systematic review. J. Infect. Dis. 2022, 226, 1593–1607. [Google Scholar] [CrossRef]
  3. Office for National Statistics. Prevalence of Long COVID Symptoms and Associated Activity Limitations; Office for National Statistics: London, UK, 2023. [Google Scholar]
  4. Ewing, A.G.; Salamon, S.; Pretorius, E.; Joffe, D.; Fox, G.; Bilodeau, S.; Bar-Yam, Y. Review of organ damage from COVID and Long COVID: A disease with a spectrum of pathology. Med. Rev. 2024, 5, 66–75. [Google Scholar] [CrossRef]
  5. Xu, Z.; Shi, L.; Wang, Y.; Zhang, J.; Huang, L.; Zhang, C.; Liu, S.; Zhao, P.; Liu, H.; Zhu, L.; et al. Pathological findings of COVID-19 associated with acute respiratory distress syndrome. Lancet Respir. Med. 2020, 8, 420–422, Erratum in Lancet Respir. Med. 2020, 8, 420–422. [Google Scholar] [CrossRef]
  6. Gheblawi, M.; Wang, K.; Viveiros, A.; Nguyen, Q.; Zhong, J.C.; Turner, A.J.; Raizada, M.K.; Grant, M.B.; Oudit, G.Y. Angiotensin-converting enzyme 2: SARS-CoV-2 receptor and regulator of the renin-angiotensin system. Circ. Res. 2020, 126, 1456–1474. [Google Scholar] [CrossRef]
  7. Mustafa, M.I.; Abdelmoneim, A.H.; Mahmoud, E.M.; Makhawi, A.M. Cytokine storm in COVID-19 patients, its impact on organs and potential treatment by QTY code-designed detergent-free chemokine receptors. Mediat. Inflamm. 2020, 2020, 8198963. [Google Scholar] [CrossRef]
  8. Daynes, E.; Evans, R.A.; Greening, N.J.; Bishop, N.C.; Yates, T.; Lozano-Rojas, D.; Ntotsis, K.; Richardson, M.; Baldwin, M.M.; Hamrouni, M.; et al. Post-Hospitalisation COVID-19 Rehabilitation (PHOSP-R): A randomised controlled trial of exercise-based rehabilitation. Eur. Respir. J. 2025, 65, 2402152. [Google Scholar] [CrossRef] [PubMed]
  9. Sick, J.; Steinbacher, V.; Kotnik, D.; König, F.; Recking, T.; Bengsch, D.; König, D. Exercise rehabilitation in post COVID-19 patients: A randomized controlled trial of different training modalities. Eur. J. Phys. Rehabil. Med. 2025, 61, 130–140. [Google Scholar] [CrossRef] [PubMed]
  10. McGregor, G.; Sandhu, H.; Bruce, J.; Sheehan, B.; McWilliams, D.; Yeung, J.; Jones, C.; Lara, B.; Alleyne, S.; Smith, J.; et al. Clinical effectiveness of an online supervised group physical and mental health rehabilitation programme for adults with post-covid-19 condition (REGAIN study): Multicentre randomised controlled trial. BMJ 2024, 384, e076506, Erratum in BMJ 2024, 385, q988. [Google Scholar] [CrossRef] [PubMed]
  11. Zheng, C.; Chen, X.-K.; Sit, C.H.-P.; Liang, X.; Li, M.-H.; Ma, A.C.-H.; Wong, S.H.-S. Effect of Physical Exercise–Based Rehabilitation on Long COVID: A Systematic Review and Meta-analysis. Med. Sci. Sports Exerc. 2023, 56, 143–154. [Google Scholar] [CrossRef]
  12. Wright, J.; Astill, S.L.; Sivan, M. The Relationship Between Physical Activity and Long COVID: A Cross-Sectional Study. Int. J. Environ. Res. Public Health 2022, 19, 5093. [Google Scholar] [CrossRef]
  13. Pringle, A.; Parnell, D.; Zwolinsky, S.; Hargreaves, J.; McKenna, J. Effect of a health-improvement pilot programme for older adults delivered by a professional football club: The Burton Albion case study. Soccer Soc. 2014, 15, 902–918. [Google Scholar] [CrossRef]
  14. Rutherford, Z.; Zwolinsky, S.; Kime, N.; Pringle, A. A Mixed-Methods Evaluation of CARE (Cancer and Rehabilitation Exercise): A Physical Activity and Health Intervention, Delivered in a Community Football Trust. Int. J. Environ. Res. Public Health 2021, 18, 3327. [Google Scholar] [CrossRef]
  15. RE-AIM. Home–Reach Effectiveness Adoption Implementation Maintenance. RE-AIM. 2025. Available online: https://re-aim.org/ (accessed on 1 December 2023).
  16. Cotler, J.; Holtzman, C.; Dudun, C.; Jason, L.A. A Brief Questionnaire to Assess Post-Exertional Malaise. Diagnostics 2018, 8, 66. [Google Scholar] [CrossRef]
  17. Vøllestad, N.K.; Mengshoel, A.M. Post-exertional malaise in daily life and experimental exercise models in patients with myalgic encephalomyelitis/chronic fatigue syndrome. Front. Physiol. 2023, 14, 1257557. [Google Scholar] [CrossRef]
  18. Svensson, P.; Hellberg, M.; Zhou, Y.; Wisén, A.; Clyne, N. The Borg scale is a sustainable method for prescribing and monitoring self-administered aerobic endurance exercise in patients with chronic kidney disease. Eur. J. Physiother. 2022, 25, 265–273. [Google Scholar] [CrossRef]
  19. Topouchian, J.; Hakobyan, Z.; Asmar, J.; Gurgenian, S.; Zelveian, P.; Asmar, R. Clinical accuracy of the Omron M3 Comfort® and the Omron Evolv® for self-blood pressure measurements in pregnancy and pre-eclampsia—Validation according to the Universal Standard Protocol. Vasc. Health Risk Manag. 2018, 14, 189–197. [Google Scholar] [CrossRef]
  20. Salter. Pulse Oximeter. Available online: https://salter.com/oxywatch-fingertip-pulse-oximeter/ (accessed on 4 January 2024).
  21. Health Management. Respiratory Muscle Exerciser/Hand-Held MicroRPM. Available online: https://healthmanagement.org/c/icu/products/respiratory-muscle-exerciser-hand-held-microrpm (accessed on 17 October 2025).
  22. Sport England. Active Lives Adult Survey: November 2017–November 2018; Sport England: Loughborough, UK, 2018. [Google Scholar]
  23. National Health Service (NHS) Foundation Trust. Six-Minute Walk and One-Minute Sit to Stand Tests. Royal Brompton & Harefield Hospitals. Available online: https://www.rbht.nhs.uk/our-services/heart/pulmonary-hypertension-service/tests (accessed on 5 December 2023).
  24. Read, J.R.; Sharpe, L.; Modini, M.; Dear, B.F. Multimorbidity and depression: A systematic review and meta-analysis. J. Affect. Disord. 2017, 221, 36–46. [Google Scholar] [CrossRef] [PubMed]
  25. Spitzer, R.L.; Kroenke, K.; Williams, J.B.W.; Löwe, B. A Brief Measure for Assessing Generalized Anxiety Disorder: The GAD-7: The GAD-7. Arch. Intern. Med. 2006, 166, 1092–1097. [Google Scholar] [CrossRef] [PubMed]
  26. Muls, A.; Georgopoulou, S.; Hainsworth, E.; Hartley, B.; O’Gara, G.; Stapleton, S.; Cruickshank, S. The psychosocial and emotional experiences of cancer patients during the COVID-19 pandemic: A systematic review. In Seminars in Oncology; Elsevier: Amsterdam, The Netherlands, 2022. [Google Scholar]
  27. Gilbody, S.; Richards, D.; Brealey, S.; Hewitt, C. Screening for Depression in Medical Settings with the Patient Health Questionnaire (PHQ): A Diagnostic Meta-Analysis. J. Gen. Intern. Med. 2007, 22, 1596–1602. [Google Scholar] [CrossRef] [PubMed]
  28. Public Health Scotland. The Short Warwick-Edinburgh Mental Wellbeing Scale (SWEMWBS); NHS Health Scotland: Edinburgh, UK, 2021. [Google Scholar]
  29. Wyke, S.; Hunt, K.; Gray, C.M.; Fenwick, E.; Bunn, C.; Donnan, P.T.; Rauchhaus, P.; Mutrie, N.; Anderson, A.S.; Boyer, N.; et al. Football Fans in Training (FFIT): A randomised controlled trial of a gender-sensitised weight loss and healthy living programme for men—End of study report. Public Health Res. 2015, 3, 1–130. [Google Scholar] [CrossRef]
  30. Pringle, A.; Zwolinsky, S.; McKenna, J.; Robertson, S.; Daly-Smith, A.; White, A. Health improvement for men and hard-to-engage-men delivered in English Premier League football clubs. Health Educ. Res. 2014, 29, 503–520. [Google Scholar] [CrossRef]
  31. Braun, V.; Clarke, V. One size fits all? What counts as quality practice in (reflexive) thematic analysis? Qual. Res. Psychol. 2021, 18, 328–352. [Google Scholar] [CrossRef]
  32. Nakagawa, S.; Cuthill, I.C. Effect size, confidence interval and statistical significance: A practical guide for biologists. Biol. Rev. 2007, 82, 591–605. [Google Scholar] [CrossRef]
  33. Lakens, D. Calculating and reporting effect sizes to facilitate cumulative science: A practical primer for t-tests and ANOVAs. Front. Psychol. 2013, 4, 863. [Google Scholar] [CrossRef] [PubMed]
  34. Cohen, J. Statistical Power Analysis for the Behavioral Sciences; Lawrence Erlbaum Associates: Hillsdale, NJ, USA, 1988. [Google Scholar]
  35. Gerlis, C.; Barradell, A.; Gardiner, N.Y.; Chaplin, E.; Goddard, A.; Singh, S.J.; Daynes, E. The Recovery Journey and the Rehabilitation Boat—A qualitative study to explore experiences of COVID-19 rehabilitation. Chronic Respir. Dis. 2022, 19. [Google Scholar] [CrossRef] [PubMed]
  36. Owen, R.; Ashton, R.E.; Skipper, L.; Phillips, B.E.; Yates, J.; Thomas, C.; Ferraro, F.; Bewick, T.; Haggan, K.; Faghy, M.A. Long COVID quality of life and healthcare experiences in the UK: A mixed method online survey. Qual. Life Res. 2023, 33, 133–143. [Google Scholar] [CrossRef] [PubMed]
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