Next Article in Journal
Contextualizing Evidence for Action on Diabetes in Low-Resource Settings—Project CEAD Part I: A Mixed-Methods Study Protocol
Previous Article in Journal
Psychological Wellbeing in Adolescents with Leukaemia: A Comparative Study with Typical Development Peers
Previous Article in Special Issue
Cat and Dog Ownership in Early Life and Infant Development: A Prospective Birth Cohort Study of Japan Environment and Children’s Study
Open AccessArticle

Use of Medications by Breastfeeding Women in the 2015 Pelotas (Brazil) Birth Cohort Study

1
Department of Social Medicine, Faculty of Medicine, Federal University of Pelotas, Avenida Duque de Caxias, 250, Pelotas 96030-000, RS, Brazil
2
Post-Graduate Program in Epidemiology, Federal University of Pelotas, Rua Marechal Deodoro, 1160, Pelotas 96020-220, RS, Brazil
3
Centre for Global Child Health, Hospital for Sick Children, 555 University Avenue, Toronto, ON M5G 1X8, Canada
4
Department of Paediatrics, University of Toronto, 555 University Avenue, Toronto, ON M5G 1X8, Canada
5
Department of Physiology and Pharmacology, Institute of Biology, Federal University of Pelotas, Travessa André Dreyfus, s/n, Campus Capão do Leão, Pelotas 96010-900, RS, Brazil
6
Post-Graduate Program in Epidemiology, Federal University of Porto Alegre, Av. Ipiranga, 2752, Sala 203, Porto Alegre 96020-000, RS, Brazil
*
Author to whom correspondence should be addressed.
Int. J. Environ. Res. Public Health 2020, 17(2), 568; https://doi.org/10.3390/ijerph17020568
Received: 1 August 2019 / Revised: 14 November 2019 / Accepted: 9 January 2020 / Published: 16 January 2020
(This article belongs to the Special Issue Population-Based Birth Cohort Studies in Epidemiology)
Background: This study describes medication use by women up to 3 months postpartum and evaluates the association between medication use by women who were still breastfeeding at 3 months postpartum and weaning at 6 and 12 months. Methods: Population-based cohort, including women who breastfed (n = 3988). Medications were classified according to Hale’s lactation risk categories and Brazilian Ministry of Health criteria. Duration of breastfeeding was analysed using Cox regression models and Kaplan-Meier curves, including only women who were still breastfeeding at three months postpartum. Results: Medication use with some risk for lactation was frequent (79.6% regarding Hale’s risk categories and 12.3% regarding Brazilian Ministry of Health criteria). We did not find statistically significant differences for weaning at 6 or 12 months between the group who did not use medication or used only compatible medications and the group who used medications with some risk for lactation, according to both criteria. Conclusions: Our study found no association between weaning rates across the different breastfeeding safety categories of medications in women who were still breastfeeding at three months postpartum. Therefore, women who took medications and stopped breastfeeding in the first three months postpartum because of adverse side-effects associated with medications could not be addressed in this analysis. View Full-Text
Keywords: pharmacoepidemiology; breastfeeding; drug utilization; pharmaceutical preparations; cohort studies; weaning; risk assessment pharmacoepidemiology; breastfeeding; drug utilization; pharmaceutical preparations; cohort studies; weaning; risk assessment
Show Figures

Figure 1

MDPI and ACS Style

Lutz, B.H.; Bassani, D.G.; Miranda, V.I.A.; Silveira, M.P.T.; Mengue, S.S.; Dal Pizzol, T.S.; da Silveira, M.F.; Bertoldi, A.D. Use of Medications by Breastfeeding Women in the 2015 Pelotas (Brazil) Birth Cohort Study. Int. J. Environ. Res. Public Health 2020, 17, 568.

Show more citation formats Show less citations formats
Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Article Access Map by Country/Region

1
Back to TopTop