Review of Non-Respiratory, Non-Cancer Physical Health Conditions from Exposure to the World Trade Center Disaster
Abstract
:1. Introduction
2. Methods
2.1. Search Strategy
2.2. Inclusion Criteria
2.3. Study Selection
3. Results
3.1. Cardiovascular/Cerebrovascular Diseases
3.2. Autoimmune Diseases
3.3. Gastroesophageal Reflux Disease/Gastrointestinal Conditions
3.4. Obstructive Sleep Apnea
3.5. Skin Conditions
3.6. Rhinosinusitis
3.7. Other Emerging Conditions
4. Discussion
5. Conclusions
Acknowledgments
Author Contributions
Conflicts of Interest
References
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Author, Year | Condition | Study Design | Data Source of Condition | Population | Sample Size of Interest |
---|---|---|---|---|---|
Alper et al., 2017 [18] | Cardiovascular disease | Cohort | Self-report | WTC Health Registry Adult enrollees (18–64 years old) | 8701 |
Brackbill et al., 2014 [16] | Cardiovascular disease | Cohort | Self-report | WTC Health Registry Adult enrollees (18–63 years old) | 14,087 |
Jordan et al., 2011 [17] | Cardiovascular disease | Cohort | Self-report | WTC Health Registry: Residence of lower Manhattan and Rescue and Recovery Workers | 39,324 |
Jordan et al., 2013 [13] | Cardiovascular disease | Cohort | Hospitalization records | WTC Health Registry: Residence of lower Manhattan and Rescue and Recovery Workers who lived in New York State | 46,417 |
Lin et al., 2010 [14] | Cardiovascular disease | Case-Control | Hospitalization records | Affected population in Manhattan living near Ground Zero; Control population in Queens County | Affected population: 56,013 Control population: 88,017 |
Mani et al., 2012 [10] | Cardiovascular disease | Cohort | Clinical assessment | WTCHC: Rescue and Recovery Workers (Law Enforcement) | 31 |
Moline et al., 2016 [11] | Cardiovascular disease | Cohort | Clinical assessment | WTCHC: Rescue and Recovery Workers (Law Enforcement) | 2497 |
Jordan et al., 2011 [37] | Autoimmune disease (sarcoidosis) | Case-control | Clinical assessment | WTC Health Registry: Residence of lower Manhattan and Rescue and Recovery Workers | Cases: 28 Controls: 109 |
Loupasakis et al., 2015 [31] | Autoimmune disease (sarcoid arthritis) | Cohort | Clinical assessment | FDNY: Rescue and Recovery Workers | 13,468 |
Webber et al., 2015 [32] | Autoimmune disease (systemic autoimmune diseases) | Case-control | Clinical assessment | FDNY: Rescue and Recovery Workers | Cases: 59 Controls: 236 |
Webber et al., 2016 [33] | Autoimmune disease (systemic autoimmune diseases) | Case-cohort | Clinical assessment | FDNY: Rescue and Recovery Workers | 13,892 |
Webber et al., 2017 [34] | Autoimmune disease (sarcoidosis) | Case-cohort | Clinical assessment | FDNY: Rescue and Recovery Workers (Firefighters and EMT) | 13,098 |
Li et al., 2011 [44] | GERD/GI | Cohort | Self-report | WTC Health Registry: Residence of lower Manhattan and Rescue and Recovery Workers | 37,118 |
Li et al., 2016 [54] | GERD/GI | Cohort | Self-report | WTC Health Registry: Residence of lower Manhattan and Rescue and Recovery Workers | 29,406 |
Litcher-Kelly et al., 2014 [53] | GERD | Cohort | Clinical assessment | WTCHC: Rescue and Recovery Workers (Law Enforcement and Nontraditional) | 10,953 |
Webber et al., 2009 [46] | GERD/GI | Cohort | Self-report | FDNY: Rescue and Recovery Workers | 10,378 |
Glaser et al., 2014 [56] | Obstructive sleep apnea | Cross-sectional | Clinical assessment | FDNY: Rescue and Recovery Workers | 636 |
Webber et al., 2011 [55] | Obstructive sleep apnea | Cohort | Self-report | FDNY: Rescue and Recovery Workers | 13,330 |
Huang et al., 2012 [61] | Skin rash or irritation | Cohort | Self-report | WTC Health Registry: Residence of lower Manhattan and Rescue and Recovery Workers | 42,025 |
Weakley et al., 2015 [63] | Rhinosinusitis | Cohort | Clinical assessment | FDNY: Rescue and Recovery Workers | 9848 |
Miller-Archie et al., 2014 [64] | Other (diabetes) | Cohort | Self-report | WTC Health Registry: Residence of lower Manhattan and Rescue and Recovery Workers | 36,899 |
Stein et al., 2017 [69] | Other (hearing loss) | Cohort | Self-report | WTC Health Registry: Rescue and Recovery Workers | 16,579 |
Tapp et al., 2005 [65] | Other (headaches) | Cross-sectional | Self-report | NYC Transit Workers | 269 |
Multiple conditions | |||||
Brackbill et al., 2006 [15] | GERD/GI, Other (headaches, hearing problems/loss), Skin rash, Cardiovascular disease | Cohort | Self-report | WTC Health Registry Adult enrollees (survivors of collapsed and damage buildings) | 8418 |
Liu et al., 2017 [52] | Rhinosinusitis; GERD | Cohort | Clinical assessment | FDNY: Rescue and Recovery Workers | 8968 |
Perritt et al., 2011 [12] | Cardiovascular disease; GERD/GI; Skin rash/irritation; Other (headaches) | Cohort | Self-report | WTCHC: Rescue and Recovery Workers and Volunteers | 7810 |
Wisnivesky et al., 2011 [45] | Rhinosinusitis; GERD | Cohort | Self-report | WTCHC: Rescue and Recovery Workers; Construction Workers; Municipal Workers | 27,449 |
Yip et al., 2016 [50] | Rhinosinusitis; GERD | Cohort | Clinical assessment | FDNY: Rescue and Recovery Workers (EMT) | 2281 |
Author, Year | Condition | 9/11-Exposure | Comorbid Conditions Reported |
---|---|---|---|
Alper et al., 2017 [18] | Cardiovascular disease | Injury | PTSD |
Brackbill et al., 2006 [15] | GERD/GI, Other (headaches, hearing problems/loss), Skin rash, Cardiovascular disease (heart disease, stroke, hypertension) | Dust/debris cloud; building type | None assessed |
Brackbill et al., 2014 [16] | Cardiovascular disease | Injury | PTSD |
Glaser et al., 2014 [56] | Obstructive sleep apnea | Arrival to Ground Zero on 9/11 | GERD and comorbid GERD/Rhinosinusitis |
Huang et al., 2012 [61] | Skin rash or irritation | Dust/debris cloud; home/workplace damage; working more than 90 days or 31 to 90 days at the World Trade Center site | None found |
Icitovic et al., 2016 [49] | GERD/GI | RRW | Obesity |
Jiang et al., 2016 [51] | GERD/GI | RRW | None assessed |
Jordan et al., 2011 [37] | Autoimmune disease (sarcoidosis) | Worked on the pile at ground zero on 9/11 | None assessed |
Jordan et al., 2011 [17] | Cardiovascular disease | Dust cloud (women); injury (men and women) | PTSD |
Jordan et al., 2013 [13] | Cardiovascular disease | RRW | PTSD |
Li et al., 2011 [44] | GERD/GI | RRW; dust cloud; not evacuating home (residents) | PTSD; asthma; PTSD/asthma comorbidity |
Li et al., 2016 [54] | GERD/GI | RRW | PTSD; asthma |
Lin et al., 2010 [14] | Cardiovascular disease | Resident proximity to Ground Zero | None assessed |
Litcher-Kelly et al., 2014 [53] | GERD | RRW; worked on the pile at ground zero on 9/11 | Depression; generalized anxiety; panic; PTSD |
Liu et al., 2017 [52] | Rhinosinusitis; GERD | Arrival to Ground Zero on 9/11 | OAD |
Loupasakis et al., 2015 [31] | Autoimmune disease (sarcoid arthritis) | RRW | None assessed |
Mani et al., 2012 [10] | Cardiovascular disease | Arrival to Ground Zero on 9/11 | None assessed |
Miller-Archie et al., 2014 [64] | Other (diabetes) | Exposure index (Very high/high) | PTSD |
Moline et al., 2016 [11] | Cardiovascular disease | RRW | None assessed |
Perritt et al., 2011 [12] | Cardiovascular disease; GERD/GI; Skin rash/irritation; Other (headaches) | RRW | None assessed |
Stein et al., 2017 [69] | Other (hearing loss) | RRW; dust cloud | PTSD |
Tapp et al., 2005 [65] | Other (headaches) | Dust cloud | None assessed |
Weakley et al., 2015 [63] | Rhinosinusitis | Earlier time of arrival at the WTC site (morning of 9/11 through 9/12) | None assessed |
Webber et al., 2009 [46] | GERD/GI | Arrival on 9/11 and prolonged work at Ground Zero | Lower respiratory symptoms; Rhinosinusitis |
Webber et al., 2011 [55] | Obstructive sleep apnea | Earlier time of arrival at the WTC site (morning of 9/11 through 9/12) | GERD; chronic rhinosinusitis; PTSD |
Webber et al., 2015 [32] | Autoimmune disease (systemic autoimmune diseases) | Prolonged work at Ground Zero | None assessed |
Webber et al., 2016 [33] | Autoimmune disease (systemic autoimmune diseases) | Arrival on 9/11 and/or prolonged work at Ground Zero | None assessed |
Webber et al., 2017 [34] | Autoimmune disease (sarcoidosis) | Arrival on 9/11 and/or prolonged work at Ground Zero | None assessed |
Wisnivesky et al., 2011 [45] | Rhinosinusitis; GERD | Dust cloud; Prolonged work at Ground Zero | GERD; asthma; Rhinosinusitis |
Yip et al., 2016 [50] | Rhinosinusitis; GERD | Earlier arrival at Ground Zero | GERD; Rhinosinusitis; obstructive airway disease; mental health disorders |
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Gargano, L.M.; Mantilla, K.; Fairclough, M.; Yu, S.; Brackbill, R.M. Review of Non-Respiratory, Non-Cancer Physical Health Conditions from Exposure to the World Trade Center Disaster. Int. J. Environ. Res. Public Health 2018, 15, 253. https://doi.org/10.3390/ijerph15020253
Gargano LM, Mantilla K, Fairclough M, Yu S, Brackbill RM. Review of Non-Respiratory, Non-Cancer Physical Health Conditions from Exposure to the World Trade Center Disaster. International Journal of Environmental Research and Public Health. 2018; 15(2):253. https://doi.org/10.3390/ijerph15020253
Chicago/Turabian StyleGargano, Lisa M., Kimberly Mantilla, Monique Fairclough, Shengchao Yu, and Robert M. Brackbill. 2018. "Review of Non-Respiratory, Non-Cancer Physical Health Conditions from Exposure to the World Trade Center Disaster" International Journal of Environmental Research and Public Health 15, no. 2: 253. https://doi.org/10.3390/ijerph15020253